Výsledky vyhledávání - "Meral Urhan Kucuk"

Behavioral and Cognitive Consequences of Obesity in Parents and Offspring in Female and Male Rats: Implications of Neuroinflammation and Neuromodulation

Autor: Enver Ahmet Demir, Gulay Gulbol-Duran, Meral Urhan-Kucuk, Hatice Dogan, Okan Tutuk, Funda Cimen, Mucella Bayirli, Cemil Tumer, Nizami Duran

Publikováno v: Molecular Neurobiology. 59:3947-3968

Obesity is a rapidly growing public health concern that can create a family-wise burden. This study was aimed to investigate behavioral, cognitive, neuroinflammatory, and neuromodulatory consequences of the diet and parental obesity. Female and male

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ea313f0a057065cd1b585aa29d9cd8
https://doi.org/10.1007/s12035-022-02831-5

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Anti-proliferative effects of beta-blocker propranolol on human lung cancer and noncancer cells

Autor: Menderes Yusuf TERZI, Meral URHAN-KUCUK

Publikováno v: Bratislavske lekarske listy.

Propranolol (PRO) has been recently discovered to possess anti-tumorigenic effects in cancer patients. So, we aimed to enlighten the in vitro effects of propranolol in A549 lung cancer cells and BEAS2B nontumoral lung cells.The gene expression levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fca07232227a0e94776768faafa391
https://pubmed.ncbi.nlm.nih.gov/36598324

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Effect of Benzimidazole Compound on Endoplasmic Reticulum Stress and Unfolded Protein Response Signaling Pathways in Hydrogen Peroxide-Induced BEAS-2B Cells

Autor: Aysel Eraslan Sakar, Meral Urhan Kucuk, Ronak Haj Ersan, Oztekin Algul

The main aim of the study was to reveal the effects of endoplasmic reticulum (ER) stress on human bronchial epithelial cells BEAS-2B at gene and protein levels under oxidative stress conditions. The second aim of the study was to investigate whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f954318b5f1c7f27537952894a81c947
https://doi.org/10.21203/rs.3.rs-2332298/v1

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Effects of Interactions among Gene Polymorphisms of the Renin–Angiotensin-Aldosterone System on Hypertension in Turkish People from Southeast Anatolia

Autor: Aysegul Bayramoglu, Arif Suner, Meral Urhan-Kucuk, Halil Ibrahim Guler, Abdullah Arpaci, Sevim Karakas-Celik, Hasret Ecevit

Publikováno v: Romanian Journal of Laboratory Medicine, Vol 27, Iss 2, Pp 159-168 (2019)

WOS: 000467103000005
Introduction: Hypertension (HT) is characterized by high blood pressure. The reninangiotensin-aldosterone system (RAAS) plays a crucial role in blood pressure (BP) regulation by maintaining vascular tone and the water-sodium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6379fd6b56adc5389d7af6da5aee385b
https://doi.org/10.2478/rrlm-2019-0011

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Genetic variations of Renin-angiontensin and Fibrinolytic systems and susceptibility to coronary artery disease: a population genetics perspective

Autor: Meral Urhan Kucuk, Gokhan Bayramoglu, Aysegul Bayramoglu, Abdullah Arpaci, Halil Ibrahim Guler

Publikováno v: Minerva Cardiology and Angiology.

BACKGROUND Genetic predisposition is an important risk factor in coronary artery disease (CAD).This study was conducted to determine the polymorphism frequencies of the plasminogen activator inhibitor-1(PAI-1) gene 4G/5G, Angiotensin-converting enzym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6892956453d7f4108873828fa4a2359
https://doi.org/10.23736/s0026-4725.20.05212-3

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Investigation of New Benzimidazole Derivative Compounds’ Effects on A549 Cell Line

Autor: Menderes Yusuf Terzi, Gulay Gulbol Duran, Oztekin Algul, Meral Urhan Kucuk

Publikováno v: Brazilian Archives of Biology and Technology v.63 2020
Brazilian Archives of Biology and Technology
Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
Brazilian Archives of Biology and Technology, Vol 63 (2020)
Brazilian Archives of Biology and Technology, Volume: 63, Article number: e20190364, Published: 31 AUG 2020

Chronic inflammation is a common indication of several diseases, e.g. asthma, chronic obstructive pulmonary disease (COPD), atherosclerosis, etc. Benzimidazole derivatives are preferable compounds to design new analgesic and anti-inflammatory substan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0f5e38858874687e4877df699ea1c1
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132020000100317

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Pro-Enflamatuvar Sitokin IL-1β'nın İnsan Akciğer Kanseri Hücrelerinde Urotensin II Gen Ekspresyonu Üzerine Etkisi

Autor: Menderes Yusuf Terzi, Hamza Malik Okuyan, Meral Urhan Kucuk, Cansu Önlen Güneri

Publikováno v: Konuralp Tıp Dergisi. 10:354-359

Amac: Akciger kanseri dunya capinda en olumcul kanser turudur. Akciger kanseri hastalarinin kotu prognozu ve etkili tedavinin olmamasi akciger kanseri patogenezinin ayrintili olarak anlasilmasini gerektirir. Bazi calismalarda, U-II'nin akciger kanser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4083ed412088bb78924e641f7e68c6b5
https://doi.org/10.18521/ktd.398669

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Suppressive effect of Rho-kinase inhibitors Y-27632 and fasudil on spike-and-wave discharges in genetic absence epilepsy rats from Strasbourg (GAERS)

Autor: Nihan Çarçak, Melis Yavuz, Filiz Onat, Tugba Karamahmutoglu, Akif Hakan Kurt, Meral Urhan Kucuk, Kansu Büyükafşar

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 391:1275-1283

Rho/Rho-kinase (ROCK) signaling contributes to neuroinflammation, epileptogenesis, and seizures in convulsive-type epilepsies. However, this pathway has not been investigated in absence epilepsy. We investigated RhoA activity in genetic absence epile

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894fa9e8f9cd03c674b494e2ca74512e
https://doi.org/10.1007/s00210-018-1546-9

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Investigation of polymerase chain reaction method in patients with suspected chronic cutaneous leishmania of negative microscopy

Autor: Gulay Gulbol Duran, Meral Urhan Kucuk, Asena Çiğdem Doğramacı, Gülnaz Çulha, Tuğba Kaya, Dilek Tiyekli Çelik

Leyşmanyazis, enfekte dişi tatarcıkların ısırmasıyla insanlara bulaşan paraziter bir hastalıktır. Kutanöz leyşmanyazisin (KL) tanısında dermal kazıntıdan alınan örneklerde, mikroskopta parazitin gösterilmesi altın standart bir yö

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19491066d6c00727b210c9634198002b
https://hdl.handle.net/20.500.12483/3122

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Is there any role of G-protein estrogen receptor gene (GPR30) polymorphism in development of schizophrenia?

Autor: Murat Eren Özen, Mehmet Bertan Yilmaz, Miriş Dikmen, Sinan Özler, Meral Urhan Kucuk, Duygu Tap

Objectives: Schizophrenia is a complex neuropsychiatric disorder that affects approximately 1% of the population. Estrogens may play an important role in the etiology and treatment of this disorder. They mediate effect by either estrogen receptors. G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9332855f280ca1ca1263f2a8e2312f2
https://hdl.handle.net/20.500.12605/9087

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