Výsledky vyhledávání - "Meral Sakizli"

Glial cell-derived neurotrophic factor gene polymorphisms affect severity and functionality of bipolar disorder

Autor: Deniz Ceylan, Ayşegül Özerdem, Zeliha Tunca, Yaprak Yalçın, Roghaiyeh Safari, Meral Sakizli

Publikováno v: Journal of Integrative Neuroscience. 16:471-481

Glial cell-derived neurotrophic factor and other neurotrophins have important role in the development of mental disorders. Here, we aimed to assess the effects of Single nucleotide polymorphisms at potentially regulated regions of GDNF on severity an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2020cd9ed7378520702335eb5ed2baad
https://doi.org/10.3233/jin-170031

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Mutation/SNP analysis in EF-hand calcium binding domain of mitochondrial Ca[Formula: see text] uptake 1 gene in bipolar disorder patients

Autor: Roghaiyeh, Safari, Reza, Salimi, Zeliha, Tunca, Aysegul, Ozerdem, Deniz, Ceylan, Meral, Sakizli

Publikováno v: Journal of integrative neuroscience. 15(2)

Calcium signaling is important for synaptic plasticity, generation of brain rhythms, regulating neuronal excitability, data processing and cognition. Impairment in calcium homeostasis contributed to the development of psychiatric disorders such as bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae8da697056ca115bb67ff8eb5d37add
https://pubmed.ncbi.nlm.nih.gov/27297032

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Mutation/SNP analysis in EF-hand calcium binding domain of mitochondrial Ca2+ uptake 1 gene in bipolar disorder patients

Autor: Deniz Ceylan, Reza Salimi, Meral Sakizli, Ayşegül Özerdem, Roghaiyeh Safari, Zeliha Tunca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e2a49acf48d7e10d16cca255fe5478
https://avesis.deu.edu.tr/publication/details/b3b25d80-e904-486a-9e0f-6b57d14f7e7f/oai

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Promoter methylation and expression changes of CDH1 and P16 genes in invasive breast cancer and adjacent normal breast tissue

Autor: Serdar Saydam, A Celebiler Cavusoglu, Meral Sakizli, Zuhal Başkan, Ali İbrahim Sevinç, Y. Kılıç, Tülay Canda

Publikováno v: Neoplasma. 57:465-472

We studied the promoter methylation status and expression levels of P16 and CDH1 genes in breast cancer and their adjacent normal tissues with normal control breast tissues, to correlate with their histopathological parameters. Hundred twenty four sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2625f04555a9c47f7f11c254485712
https://doi.org/10.4149/neo_2010_05_465

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TLR-2 Arg753Gln, TLR-4 Asp299Gly, and TLR-4 Thr399Ile polymorphisms in Henoch Schonlein purpura with and without renal involvement

Autor: Salih Kavukçu, Mehmet Türkmen, Alper Soylu, Sefa Kizildag, Sultan Cingoz, Belde Kasap Demir, Meral Sakizli

Publikováno v: Rheumatology International. 30:667-670

Infections may trigger or aggravate glomerulonephritidis and renal vasculitis like Henoch Schonlein purpura (HSP). HSP is seen more frequently in patients with familial Mediterranean fever in which TLR-2 Arg753Gln polymorphism frequency is increased.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73762c0704d2fa50a0cf6490ac79d50d
https://doi.org/10.1007/s00296-009-1052-y

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Familial pericentric inversion chromosome 3 and R448C mutation of CYP11B1 gene in Turkish kindred with 11β-hydroxylase deficiency

Autor: Meral Sakizli, H. Döneray, Sultan Cingoz, B. Özkan

Publikováno v: Journal of Endocrinological Investigation. 30:285-291

11 beta-hydroxylase deficiency is the second most common cause of congenital adrenal hyperplasia (CAH). This isoenzyme is coded by two highly homologous genes of cytochrome P450: CYP11B1 and CYP11B2 which were mapped to the chromosomal band 8q24. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577664c08976b324a92deb2360850ea6
https://doi.org/10.1007/bf03346295

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Correlation of modified Shimada classification with MYCN and 1p36 status detected by fluorescence in situ hybridization in neuroblastoma

Autor: Sait Tumer, Meral Sakizli, Oguz Altungoz, Erdener Özer, Nevim Aygun, Nur Olgun

Publikováno v: Cancer Genetics and Cytogenetics. 172:113-119

Neuroblastoma (NB) is a childhood cancer derived from neural crest cells, with a highly variable clinical course and biologic behavior. NB cells harbor complex genetic changes. Also, MYCN amplification is a well-known Molecular marker for aggressive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295edefd10369cc463e2fc8041051420
https://doi.org/10.1016/j.cancergencyto.2006.10.005

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İmatinib Mesilat ile Tedavi Edilen Kronik Myeloid Lösemi Vakalarında Belirlenen Trizomi 8

Autor: YÜKSEL, Erdinç, ÖZCAN, Mehmet Ali, SERCAN, Zeynep, ŞAMLI, Hale, BÜYÜKKEÇECİ, Filiz, SOLAK, Mustafa, Meral SAKIZLI

Publikováno v: Volume: 6, Issue: 2 7-10
Kocatepe Tıp Dergisi

Kronik myeloid lösemi vakalarında t(9;22)(q34;q11) translokasyonu sonucu Philadelphia (Ph) kromozomu oluşmakta ve bu translokasyon bcr-abl gen füzyonuna yol açmaktadır. İmatinib mesilat (STI571, Glivec) bcr-abl gen füzyonu sonucu sentezlenen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=tubitakulakb::f4d7af15c84ef7d322914b32f5365faf
https://dergipark.org.tr/tr/pub/kocatepetip/issue/17425/182484

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