Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Meraj Ramezani"'
Autor:
Meraj Ramezani, Alice Wagenknecht-Wiesner, Tong Wang, David A. Holowka, David Eliezer, Barbara A. Baird
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-18 (2023)
Abstract Alpha synuclein (a-syn) is an intrinsically disordered protein prevalent in neurons, and aggregated forms are associated with synucleinopathies including Parkinson’s disease (PD). Despite the biomedical importance and extensive studies, th
Externí odkaz:
https://doaj.org/article/cd9587de17e542339557bedbf39af0c3
Autor:
Tapojyoti Das, Meraj Ramezani, David Snead, Cristian Follmer, Peter Chung, Ka Yee Lee, David A. Holowka, Barbara A. Baird, David Eliezer
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1816 (2022)
Alpha-synuclein is a presynaptic protein linked to Parkinson’s disease with a poorly characterized physiological role in regulating the synaptic vesicle cycle. Using RBL-2H3 cells as a model system, we earlier reported that wild-type alpha-synuclei
Externí odkaz:
https://doaj.org/article/f60c6c30da694b5eb9dac1e470eda639
Autor:
Meraj Ramezani, Alice Wagenknecht-Wiesner, Tong Wang, David A. Holowka, David Eliezer, Barbara A. Baird
Alpha synuclein (a-syn) is an intrinsically disordered protein prevalent in neurons, and aggregated forms are associated with synucleinopathies including Parkinson’ disease (PD). Despite the biomedical importance and extensive studies, the physiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f2347969b2952300cbc5d0445daaa84
https://doi.org/10.1101/2023.04.23.537965
https://doi.org/10.1101/2023.04.23.537965
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619438
Methods Mol Biol
Methods Mol Biol
Cell surface receptors that bind the Fc segment of antibodies to initiate signaling play fundamental roles in immune responses. Multiple, diverse Fc receptors (e.g., Fc gamma, Fc-alpha, and Fc-epsilon) are expressed on different immune cells, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5bdd6abbf327f11498aec74b4e76d7a
https://doi.org/10.1007/978-1-0716-1944-5_1
https://doi.org/10.1007/978-1-0716-1944-5_1
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Membrane phase behavior in cells permits transient concentration of specific proteins and lipids into dynamic nanoscopic domains. Here, we tested the existence and role of such phase behavior in endoplasmic reticulum (ER) membranes. Empl
Publikováno v:
Biophysical Journal. 118:537a-538a
Publikováno v:
Biophysical Journal. 118:540a
Publikováno v:
npj Parkinson's Disease, Vol 5, Iss 1, Pp 1-17 (2019)
NPJ Parkinson's Disease
NPJ Parkinson's Disease
We characterized phenotypes in RBL-2H3 mast cells transfected with human alpha synuclein (a-syn) using stimulated exocytosis of recycling endosomes as a proxy for similar activities of synaptic vesicles in neurons. We found that low expression of a-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3fd00e8f1afe099b192107646f5772
Publikováno v:
Biophysical Journal. 116:494a
Publikováno v:
Biophysical Journal. 114:76a