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Abstract 13538: Impact of Autophagy Modulation on Apoptosis in Chemotherapy-Induced Cardiac Toxicity
Autor:
Asma Boukhalfa, Meola M Dawn, Joey LaMastro, Sally Robinson, Lin Meng, Sydney Weng, Nicholas Robinson, Greg Martin, David E Sosnovik, Robert M Blanton, Vicky Yang, Howard H Chen
Publikováno v:
Circulation. 144
Background: Cardiotoxicity due to chemotherapy remains a challenge. Cardioprotective interventions have not slowed the progression to heart failure. Cardiomyocyte (CM) death can be attributed to autophagy impairment during chemotherapy-induced toxici