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pro vyhledávání: '"Menzies Chen"'
Publikováno v:
Cell Reports, Vol 3, Iss 1, Pp 128-137 (2013)
Classic “position-effect” experiments repositioned genes near telomeres to demonstrate that the epigenetic landscape can dramatically alter gene expression. Here, we show that systematic gene knockout collections provide an exceptional resource f
Externí odkaz:
https://doaj.org/article/b3fddaff64d44eb5bf78b41925729e08
Autor:
Trey Ideker, Guillaume J. Filion, Ulrich Braunschweig, Bas van Steensel, Joke G. van Bemmel, Menzies Chen
In eukaryotes, many chromatin proteins together regulate gene expression. Chromatin proteins often direct the genomic binding pattern of other chromatin proteins, for example, by recruitment or competition mechanisms. The network of such targeting in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41c914581c4c84da57f5d432faa3bbc
https://europepmc.org/articles/PMC2813475/
https://europepmc.org/articles/PMC2813475/
Publikováno v:
Cell Reports, Vol 3, Iss 1, Pp 128-137 (2013)
SUMMARY Classic ‘‘position-effect’’ experiments repositioned genes near telomeres to demonstrate that the epigenetic landscape can dramatically alter gene expression. Here, we show that systematic gene knockout collections provide an exceptio