Zobrazeno 1 - 1
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pro vyhledávání: '"Mental Retardation/genetics/ metabolism"'
Autor:
Dominique Muller, Emmanuel Thévenot, Véronique Rousseau, Bernadette Boda, Jean-Vianney Barnier, Patricia Kreis
Publikováno v:
Journal of Biological Chemistry, Vol. 282, No 29 (2007) pp. 21497-21506
The p21-activated kinase 3 (PAK3) is one of the recently identified genes for which mutations lead to nonsyndromic mental retardation. PAK3 is implicated in dendritic spine morphogenesis and is a key regulator of synaptic functions. However, the unde