Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mensonides-Harsema"'
Autor:
Tomas Eriksson, Marguerite Mensonides-Harsema, Cooper Martin, Nafizal Hossain, Svetlana Ivanova, Lena Bergström
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:108-112
A series of fused bicyclic and urea derivatives of spirocyclic compounds were designed, synthesised and evaluated in vitro as potent CCR1 antagonists. In particular, 4 (7 nM), 44 (1.3 nM), 48 (0.89 nM) and 50 (0.63 nM) were the most potent hCCR1 anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666d917e797922f3e63ea1cdddf7ede4
https://doi.org/10.1016/j.bmcl.2013.11.062
https://doi.org/10.1016/j.bmcl.2013.11.062
Autor:
Marguerite Mensonides-Harsema, Cooper Martin, Nafizal Hossain, Jonas Bergare, Svetlana Ivanova
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:3500-3504
A series of CCR1 antagonists based upon spirocyclic compounds 1b and 2b were synthesised in which substituted aniline moiety was replaced with substituted benzamides. In vitro data revealed that CCR1 potency could be retained in such compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3feaa36d2cef1ff691ed89588cb7fd4
https://doi.org/10.1016/j.bmcl.2013.04.047
https://doi.org/10.1016/j.bmcl.2013.04.047
Autor:
Hossain, Nafizal, Mensonides-Harsema, Marguérite, Cooper, Martin E., Eriksson, Tomas, Ivanova, Svetlana, Bergström, Lena
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 January 2014 24(1):108-112
Autor:
Hossain, Nafizal, Ivanova, Svetlana, Bergare, Jonas, Mensonides-Harsema, Marguérite, Cooper, Martin E.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 June 2013 23(12):3500-3504
Publikováno v:
Hellenic journal of nuclear medicine. 14(1)
A survey in 2000 revealed that only about 30% of the prescriptions in the European pediatric population were on the basis of evidence-based medicine (EbM). Less for radiopharmaceuticals and principally for diagnostics, radiologists throughout Europe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af73850dbce07b626902299ac2c8b1e6
https://pubmed.ncbi.nlm.nih.gov/21512665
https://pubmed.ncbi.nlm.nih.gov/21512665
Autor:
H. Wikstroem, Peter de Boer, Marguerite M. Mensonides‐Harsema, Hartmunt E. Greiner, Yi Liao, Gerd D. Bartoszyk, J. Harting, Henning Boettcher
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1ce9d60ef0e0ac0ee7c1193a0354e63
https://doi.org/10.1002/chin.200020136
https://doi.org/10.1002/chin.200020136
Autor:
Marguérite M Mensonides-Harsema, Moltzen Ejner K, Håkan Wikström, Thomas I. F. H. Cremers, Jørn Arnt
Publikováno v:
Journal of Medicinal Chemistry, 45(15), 3280-3285. AMER CHEMICAL SOC
The synthesis and resolution of 1,2,3,4,10,14b-hexahydro-6-methoxy-2-methyldibenzo[cf]-pyrazino[1,2-alpha]azepin (6-methoxymianserin, 6) are described. Furthermore, the in vitro and in vivo effects of 6 and its enantiomers are presented. 6 displayed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2340097ce7c98883aef16ba301135577
https://pubmed.ncbi.nlm.nih.gov/12109911
https://pubmed.ncbi.nlm.nih.gov/12109911
Akademický článek
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Akademický článek
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Publikováno v:
Journal of Medicinal Chemistry; July 2002, Vol. 45 Issue: 15 p3280-3285, 6p