Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial

Autor: Norton, Sam, Lempp, Heidi, Opena, Maria, Subesinghe, Sujith, Garrood, Toby, Menon, Bina, Ng, Nora, Douglas, Karen, Koutsianas, Christos, Cooles, Faye, Falahee, Marie, Echavez-Naguicnic, Irene, Bharadwaj, Anurag, Villaruel, Michael, Pande, Ira, Collins, David, Pegler, Suzannah, Raizada, Sabrina, Siebert, Stefan, Fragoulis, George, Guinto, Jesusa, Galloway, James, Rutherford, Andrew, Barnes, Theresa, Jeffrey, Helen, Patel, Yusuf, Batley, Michael, O'Reilly, Brendan, Venkatachalam, Srivinisan, Sheeran, Thomas, Gorman, Claire, Reynolds, Piero, Khan, Asad, Gullick, Nicola, Banerjee, Siwalik, Mankia, Kulveer, Jordan, Deepak, Rowlands, Jane, Starmans-Kool, Mirian, Taylor, James, Nandi, Pradip, Sahbudin, Ilfita, Maybury, Mark, Hider, Samantha, Barcroft, Ann, McNally, Jeremy, Kitchen, Jo, Nisar, Muhammad, Quick, Vanessa, Cope, Andrew P ^*, Jasenecova, Marianna, Vasconcelos, Joana C, Filer, Andrew, Raza, Karim, Qureshi, Sumera, D'Agostino, Maria Antonietta, McInnes, Iain B, Isaacs, John D, Pratt, Arthur G, Fisher, Benjamin A, Buckley, Christopher D, Emery, Paul, Ho, Pauline, Buch, Maya H, Ciurtin, Coziana, van Schaardenburg, Dirkjan, Huizinga, Thomas, Toes, René, Georgiou, Evangelos, Kelly, Joanna, Murphy, Caroline, Prevost, A Toby

Publikováno v: In The Lancet 2-8 March 2024 403(10429):838-849

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Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial

Autor: Cope, Andrew P, Jasenecova, Marianna, Vasconcelos, Joana C, Filer, Andrew, Raza, Karim, Qureshi, Sumera, D'Agostino, Maria Antonietta, McInnes, Iain B, Isaacs, John D, Pratt, Arthur G, Fisher, Benjamin A, Buckley, Christopher D, Emery, Paul, Ho, Pauline, Buch, Maya H, Ciurtin, Coziana, van Schaardenburg, Dirkjan, Huizinga, Thomas, Toes, René, Georgiou, Evangelos, Kelly, Joanna, Murphy, Caroline, Prevost, A Toby, Norton, Sam, Lempp, Heidi, Opena, Maria, Subesinghe, Sujith, Garrood, Toby, Menon, Bina, Ng, Nora, Douglas, Karen, Koutsianas, Christos, Cooles, Faye, Falahee, Marie, Echavez-Naguicnic, Irene, Bharadwaj, Anurag, Villaruel, Michael, Pande, Ira, Collins, David, Pegler, Suzannah, Raizada, Sabrina, Siebert, Stefan, Fragoulis, George, Guinto, Jesusa, Galloway, James, Rutherford, Andrew, Barnes, Theresa, Jeffrey, Helen, Patel, Yusuf, Batley, Michael, O'Reilly, Brendan, Venkatachalam, Srivinisan, Sheeran, Thomas, Gorman, Claire, Reynolds, Piero, Khan, Asad, Gullick, Nicola, Banerjee, Siwalik, Mankia, Kulveer, Jordan, Deepak, Rowlands, Jane, Starmans-Kool, Mirian, Taylor, James, Nandi, Pradip, Sahbudin, Ilfita, Maybury, Mark, Hider, Samantha, Barcroft, Ann, McNally, Jeremy, Kitchen, Jo, Nisar, Muhammad, Quick, Vanessa

Publikováno v: The Lancet; March 2024, Vol. 403 Issue: 10429 p838-849, 12p

Interleukin-17+CD8+T Cells Are Enriched in the Joints of Patients With Psoriatic Arthritis and Correlate With Disease Activity and Joint Damage Progression

Autor: Menon, Bina, Gullick, Nicola, Walter, Gina, Rajasekhar, Megha, Garrood, Toby, Evans, Hayley, Taams, Leonie, Kirkham, Bruce

Publikováno v: Menon, B, Gullick, N, Walter, G, Rajasekhar, M, Garrood, T, Evans, H, Taams, L & Kirkham, B 2014, ' Interleukin-17+CD8+T Cells Are Enriched in the Joints of Patients With Psoriatic Arthritis and Correlate With Disease Activity and Joint Damage Progression ', Arthritis & rheumatology, vol. 66, no. 5, pp. 1272-1281 . https://doi.org/10.1002/art.38376

Objective. Psoriatic arthritis (PsA) is associated with HLA class I genes, in contrast to the association with HLA class II in rheumatoid arthritis (RA). Since IL-17+ cells are considered important mediators of synovial inflammation, we sought to det

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2761::83fc0a9fe67f90d23e4f362eb01ff440
https://kclpure.kcl.ac.uk/ws/files/140387711/Interleukin_17_CD8_T_Cells_Are_Enriched_TAAMS_Publishedonline28April2014_GOLD_VoR_CC_BY_.pdf

Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127^low Treg Cells in Patients With Chronic Rheumatoid Arthritis.

Autor: Walter, Gina J., Fleskens, Veerle, Frederiksen, Klaus S., Rajasekhar, Megha, Menon, Bina, Gerwien, Jens G., Evans, Hayley G., Taams, Leonie S.

Publikováno v: Arthritis & Rheumatology; Jan2016, Vol. 68 Issue 1, p103-116, 14p