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T cell neoepitope discovery in colorectal cancer by high throughput profiling of somatic mutations in expressed genes

Autor: Claudio Garavaglia, Marco Severgnini, Renato Longhi, Giulia Casorati, Michele C Romano, Norma Ferrero, Elena Orsenigo, Daniele Mennonna, Gina Mazzola, Ludovica Baldari, Elisabetta Zino, Luca Albarello, Cristina Maccalli, Marco Braga, Antonio Amoroso, Alessandro Sette, Roberta Bordoni, Luca Ghirardelli, Giorgio Parmiani, John Sidney, Gianluca De Bellis, Paolo Dellabona, Katharina Fleischhauer, Filippo Capocefalo, Alessandro Gori

Publikováno v: Gut
Gut 66 (2017): 454–463. doi:10.1136/gutjnl-2015-309453
info:cnr-pdr/source/autori:Mennonna D.; Maccalli C.; Romano M.C.; Garavaglia C.; Capocefalo F.; Bordoni R.; Severgnini M.; De Bellis G.; Sidney J.; Sette A.; Gori A.; Longhi R.; Braga M.; Ghirardelli L.; Baldari L.; Orsenigo E.; Albarello L.; Zino E.; Fleischhauer K.; Mazzola G.; Ferrero N.; Amoroso A.; Casorati G.; Parmiani G.; Dellabona P./titolo:T cell neoepitope discovery in colorectal cancer by high throughput profiling of somatic mutations in expressed genes/doi:10.1136%2Fgutjnl-2015-309453/rivista:Gut/anno:2017/pagina_da:454/pagina_a:463/intervallo_pagine:454–463/volume:66

ObjectivePatient-specific (unique) tumour antigens, encoded by somatically mutated cancer genes, generate neoepitopes that are implicated in the induction of tumour-controlling T cell responses. Recent advancements in massive DNA sequencing combined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2fea23e1c642cbcc94923ba370d490
http://europepmc.org/articles/PMC5534766