Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Menno ter Huurne"'
Publikováno v:
Open Biology, Vol 14, Iss 10 (2024)
Cardiomyocytes in the adult human heart are quiescent and those lost following heart injury are not replaced by proliferating survivors. Considerable effort has been made to understand the mechanisms underlying cardiomyocyte cell cycle exit and re-en
Externí odkaz:
https://doaj.org/article/2e876f8eb14a422e8003286459497b72
Autor:
Tianran Peng, Yanan Zhai, Yaser Atlasi, Menno ter Huurne, Hendrik Marks, Hendrik G. Stunnenberg, Wout Megchelenbrink
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-27 (2020)
Abstract Background Enhancers are distal regulators of gene expression that shape cell identity and control cell fate transitions. In mouse embryonic stem cells (mESCs), the pluripotency network is maintained by the function of a complex network of e
Externí odkaz:
https://doaj.org/article/a7e5bc5ab6f847d9aaa8ed8f93c3acaf
Autor:
Menno ter Huurne, Tianran Peng, Guoqiang Yi, Guido van Mierlo, Hendrik Marks, Hendrik G. Stunnenberg
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 175-183 (2020)
Summary: Mouse embryonic stem cells (ESCs) grown in serum-supplemented conditions are characterized by an extremely short G1 phase due to the lack of G1-phase control. Concordantly, the G1-phase-specific P53-P21 pathway is compromised in serum ESCs.
Externí odkaz:
https://doaj.org/article/c34d3da9991040b2b6484a63cb6542cf
Autor:
Ning Qing Liu, Menno ter Huurne, Luan N. Nguyen, Tianran Peng, Shuang-Yin Wang, James B. Studd, Onkar Joshi, Halit Ongen, Jesper B Bramsen, Jian Yan, Claus L. Andersen, Jussi Taipale, Emmanouil T. Dermitzakis, Richard S. Houlston, Nina C. Hubner, Hendrik G. Stunnenberg
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Functional characterisation of non-coding risk variants for colorectal cancer is missing. Here the authors conduct a large-scale proteome-wide analysis of disease associated SNPs to characterize allele-specific transcription factor binding landscape
Externí odkaz:
https://doaj.org/article/8044c297681a490eaa5ba7372d960195
Autor:
Stephanie C. M. van Dalen, Arjen B. Blom, Birgitte Walgreen, Annet W. Slöetjes, Monique M. A. Helsen, Edwin J. W. Geven, Menno ter Huurne, Thomas Vogl, Johannes Roth, Fons A. J. van de Loo, Marije I. Koenders, Louis Casteilla, Peter M. van der Kraan, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Injection of adipose-derived mesenchymal stromal cells (ASCs) into murine knee joints after induction of inflammatory collagenase-induced osteoarthritis (CiOA) reduces development of joint pathology. This protection is only achieved when
Externí odkaz:
https://doaj.org/article/6ad2b9a22dd747d49bfb41f920fc06d9
Autor:
Neda R. Mehdiabadi, Choon Boon Sim, Belinda Phipson, Ravi K.R. Kalathur, Yuliangzi Sun, Celine J. Vivien, Menno ter Huurne, Adam T. Piers, James E. Hudson, Alicia Oshlack, Robert G. Weintraub, Igor E. Konstantinov, Nathan J. Palpant, David A. Elliott, Enzo R. Porrello
Publikováno v:
Circulation. 146(14)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6d91cee8d15efceb9dad7a3a7b5cf8
https://pubmed.ncbi.nlm.nih.gov/36191067
https://pubmed.ncbi.nlm.nih.gov/36191067
Publikováno v:
Cellular and Molecular Life Sciences
During early embryonic development both the rapid increase in cell number and the expression of genes that control developmental decisions are tightly regulated. Accumulating evidence has indicated that these two seemingly independent processes are m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980e7e108eda9bfaee525d97081291d3
http://europepmc.org/articles/PMC8195903
http://europepmc.org/articles/PMC8195903
Autor:
Hendrik Marks, Guido van Mierlo, Tianran Peng, Guoqiang Yi, Menno ter Huurne, Hendrik G. Stunnenberg
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 14, Iss 2, Pp 175-183 (2020)
Stem Cell Reports, 14, 2, pp. 175-183
Stem Cell Reports, 14, 175-183
Stem Cell Reports, Vol 14, Iss 2, Pp 175-183 (2020)
Stem Cell Reports, 14, 2, pp. 175-183
Stem Cell Reports, 14, 175-183
Summary Mouse embryonic stem cells (ESCs) grown in serum-supplemented conditions are characterized by an extremely short G1 phase due to the lack of G1-phase control. Concordantly, the G1-phase-specific P53-P21 pathway is compromised in serum ESCs. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee20d2ff46003d7e28a5f8c38d5097a6
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/217134
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/217134
Autor:
Menno ter Huurne, Thomas Vogl, Louis Casteilla, Martijn H J van den Bosch, Peter L E M van Lent, Stephanie C.M. van Dalen, Annet W. Sloetjes, Fons A. J. van de Loo, Peter M. van der Kraan, Monique M. Helsen, Birgitte Walgreen, Johannes Roth, Marije I. Koenders, Arjen B. Blom, Edwin J. W. Geven
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 10
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, 10
Frontiers in Immunology, Vol 10 (2019)
Background: Injection of adipose-derived mesenchymal stromal cells (ASCs) into murine knee joints after induction of inflammatory collagenase-induced osteoarthritis (CiOA) reduces development of joint pathology. This protection is only achieved when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bbc5d7648634eac51c22793c3f5aff
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/204224
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/204224
Autor:
Hendrik G. Stunnenberg, Nina C. Hubner, Richard S. Houlston, Halit Ongen, James B. Studd, Shuang-Yin Wang, Luan Nguyen, Claus L. Andersen, Onkar Joshi, Jesper B. Bramsen, Jian Yan, Jussi Taipale, Tianran Peng, Menno ter Huurne, Emmanouil T. Dermitzakis, Ning Qing Liu
Publikováno v:
Liu, N Q, Ter Huurne, M, Nguyen, L N, Peng, T, Wang, S-Y, Studd, J B, Joshi, O, Ongen, H, Bramsen, J B, Yan, J, Andersen, C L, Taipale, J, Dermitzakis, E T, Houlston, R S, Hubner, N C & Stunnenberg, H G 2017, ' The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression ', Nature Communications, vol. 8, pp. 14418 . https://doi.org/10.1038/ncomms14418
Nature Communications, 8, 1-10
Nature Communications
Nature Communications, Vol. 8 (2017) P. 14418
Nature Communications, 8, pp. 1-10
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications, 8, 1-10
Nature Communications
Nature Communications, Vol. 8 (2017) P. 14418
Nature Communications, 8, pp. 1-10
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Genome-wide association studies have identified a great number of non-coding risk variants for colorectal cancer (CRC). To date, the majority of these variants have not been functionally studied. Identification of allele-specific transcription factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cd5dbc1a96e944a462eec1c6c39805
https://pure.au.dk/portal/da/publications/the-noncoding-variant-rs1800734-enhances-dclk3-expression-through-longrange-interaction-and-promotes-colorectal-cancer-progression(10bd73d7-545e-461b-bf4a-9f7d42d5c708).html
https://pure.au.dk/portal/da/publications/the-noncoding-variant-rs1800734-enhances-dclk3-expression-through-longrange-interaction-and-promotes-colorectal-cancer-progression(10bd73d7-545e-461b-bf4a-9f7d42d5c708).html