Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Menno C, van Zelm"'
Autor:
Gemma E. Hartley, Holly A. Fryer, Paul A. Gill, Irene Boo, Scott J. Bornheimer, P. Mark Hogarth, Heidi E. Drummer, Robyn E. O’Hehir, Emily S. J. Edwards, Menno C. van Zelm
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Booster vaccinations are recommended to improve protection against severe disease from SARS-CoV-2 infection. With primary vaccinations involving various adenoviral vector and mRNA-based formulations, it remains unclear if these differentiall
Externí odkaz:
https://doaj.org/article/4810dcb194114b479e0fd08ee345a911
Autor:
Ethan P. Oxley, Nadia J. Kershaw, Cynthia Louis, Katharine J. Goodall, Maximilian M. Garwood, Skye Min Jee Ho, Veronica T.F. Voo, Hae-Young Park, Josephine Iaria, Lilian L.L. Wong, Ariel G. Lebenbaum, Stephanie Wiranata, Ee Shan Pang, Emily S.J. Edwards, Damian B. D’Silva, Jacinta Hansen, Menno C. van Zelm, Meredith O’Keeffe, P. Mark Hogarth, Nicole M. Haynes, Nicholas D. Huntington, Ian P. Wicks, Ross A. Dickins
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114834- (2024)
Summary: T cell surface CTLA4 sequesters the costimulatory ligands CD80 and CD86 on antigen-presenting cells (APCs) to prevent autoimmunity. Therapeutic immunosuppression by recombinant CTLA4-immunoglobulin (Ig) fusion proteins, including abatacept,
Externí odkaz:
https://doaj.org/article/6c8609b2d6c447c2abb2c3c69d1e33ba
Autor:
Laura A. van der Velde, Sanne A. Beth, Trudy Voortman, Menno C. van Zelm, Henriette A. Moll, Jessica C. Kiefte-de Jong
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Suboptimal vitamin D status is common in people with celiac disease (CeD), a disease that can be characterized by the presence of serum anti-tissue transglutaminase antibodies (TG2A) (i.e., TG2A positivity). To date, it remains un
Externí odkaz:
https://doaj.org/article/bcb082ee3944424a996f05f1076d9fbe
Publikováno v:
Vaccines, Vol 12, Iss 6, p 675 (2024)
The SARS-CoV-2 pandemic has heightened concerns about immunological protection, especially for individuals with inborn errors of immunity (IEI). While COVID-19 vaccines elicit strong immune responses in healthy individuals, their effectiveness in IEI
Externí odkaz:
https://doaj.org/article/e0e0b4f140164edb84771851e96b26c8
Autor:
Kris Covens, Bert Verbinnen, Britt G. de Jong, Leen Moens, Greet Wuyts, Geert Verheyen, Kris Nys, Jonathan Cremer, Stijn Smulders, Rik Schrijvers, Andreas Weinhäusel, Séverine Vermeire, Patrick Verschueren, Ellen De Langhe, Jacques J. M. van Dongen, Menno C. van Zelm, Xavier Bossuyt
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Circulating antibody-secreting cells are present in the peripheral blood of healthy individuals reflecting the continued activity of the humoral immune system. Antibody-secreting cells typically express CD27. Here we describe and characterize a small
Externí odkaz:
https://doaj.org/article/465a656e6e214d30b01ffb99b6f8c67a
Autor:
Bruce D. Wines, Liriye Kurtovic, Halina M. Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L. Mordant, Wen Shi Lee, Nicholas A. Gherardin, Sheila K. Patel, Gemma E. Hartley, Phillip Pymm, James P. Cooney, James G. Beeson, Dale I. Godfrey, Louise M. Burrell, Menno C. van Zelm, Adam K. Wheatley, Amy W. Chung, Wai-Hong Tham, Kanta Subbarao, Stephen J. Kent, P. Mark Hogarth
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/140fea88883d408989768880a06ffb83
Autor:
Bruce D. Wines, Liriye Kurtovic, Halina M. Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L. Mordant, Wen Shi Lee, Nicholas A. Gherardin, Sheila K. Patel, Gemma E. Hartley, Phillip Pymm, James P. Cooney, James G. Beeson, Dale I. Godfrey, Louise M. Burrell, Menno C. van Zelm, Adam K. Wheatley, Amy W. Chung, Wai-Hong Tham, Kanta Subbarao, Stephen J. Kent, P. Mark Hogarth
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Joining a function-enhanced Fc-portion of human IgG to the SARS-CoV-2 entry receptor ACE2 produces an antiviral decoy with strain transcending virus neutralizing activity. SARS-CoV-2 neutralization and Fc-effector functions of ACE2-Fc decoy proteins,
Externí odkaz:
https://doaj.org/article/3a2991630f9b42fdb65b29d07a0e335f
Autor:
Daniela Kužílková, Joan Puñet-Ortiz, Pei M. Aui, Javier Fernández, Karel Fišer, Pablo Engel, Menno C. van Zelm, Tomáš Kalina
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe Human Cell Differentiation Molecules (HCDM) organizes Human Leukocyte Differentiation Antigen (HLDA) workshops to test and name clusters of antibodies that react with a specific antigen. These cluster of differentiation (CD) markers hav
Externí odkaz:
https://doaj.org/article/99232b8fae0548f5be833bcfa6d2c1c3
Autor:
Eriko Totsune, Tomohiro Nakano, Kunihiko Moriya, Daichi Sato, Dai Suzuki, Akinobu Miura, Saori Katayama, Hidetaka Niizuma, Junko Kanno, Menno C. van Zelm, Kohsuke Imai, Hirokazu Kanegane, Yoji Sasahara, Shigeo Kure
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Lipopolysaccharide-responsive beige-like anchor (LRBA) deficiency is a subtype of common variable immune deficiency (CVID). Numerous case reports and cohort studies have described a broad spectrum of clinical manifestations and variable disease pheno
Externí odkaz:
https://doaj.org/article/9715a48c5f38436bbd65b95756762c07
Autor:
Mariona Baliu-Piqué, Vera van Hoeven, Julia Drylewicz, Lotte E van der Wagen, Anke Janssen, Sigrid A Otto, Menno C van Zelm, Rob J de Boer, Jürgen Kuball, Jose AM Borghans, Kiki Tesselaar
Publikováno v:
eLife, Vol 10 (2021)
Lymphocyte numbers need to be quite tightly regulated. It is generally assumed that lymphocyte production and lifespan increase homeostatically when lymphocyte numbers are low and, vice versa, return to normal once cell numbers have normalized. This
Externí odkaz:
https://doaj.org/article/284e6b966f534a63b87407d15f4ffc95