Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mengying, Hou"'
Publikováno v:
Bioactive Materials, Vol 17, Iss , Pp 320-333 (2022)
Ischemia-reperfusion (IR) injury represents a major cause of myocardial dysfunction after infarction and thrombolytic therapy, and it is closely related to the free radical explosion and overwhelming inflammatory responses. Herein, macrophage-targeti
Externí odkaz:
https://doaj.org/article/fdada927d6b149b1b443698380c6112e
Autor:
Min, Lan, Mengying, Hou, Jing, Yan, Qiurong, Deng, Ziyin, Zhao, Shixian, Lv, Juanjuan, Dang, Mengyuan, Yin, Yong, Ji, Lichen, Yin
Publikováno v:
Nano Research. 15:9125-9134
Myocardial ischemia reperfusion (IR) injury is closely related to the overwhelming inflammation in the myocardium. Herein, cardiomyocyte-targeted nanotherapeutics were developed for the reactive oxygen species (ROS)-ultrasensitive co-delivery of dexa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109c590ce39dfa05bf8fc7d0983c7ba2
https://doi.org/10.1007/s12274-022-4553-6
https://doi.org/10.1007/s12274-022-4553-6
Publikováno v:
Acta Biomaterialia. 143:344-355
Neutrophils serve as a key contributor to the pathophysiology of myocardial ischemia reperfusion injury (MIRI), because the unregulated activation and infiltration of neutrophils lead to overwhelming inflammation in the myocardium to cause tissue dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e6b8d011e95c451f156a5fac9987d8
https://doi.org/10.1016/j.actbio.2022.02.018
https://doi.org/10.1016/j.actbio.2022.02.018
Autor:
Huihui Zhu, Xiaoyi Zhang, Shifan Xu, Jiawen Wu, Mengying Hou, Haobin Zhao, Qingchun Zhou, Xueping Zhong
Publikováno v:
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. 338:301-313
Activating transcription factor 5 (Atf5) is a member of the ATF/CREB family of transcription factors and involved in diverse cellular functions and diseases in mammals. However, the function of atf5 remains largely unknown in fish. Here, we report th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39447edf311d91ae29e27ac606ccf9f3
https://doi.org/10.1002/jez.b.23124
https://doi.org/10.1002/jez.b.23124
Autor:
Rongying Zhu, Mengying Hou, Yang Zhou, Huan Ye, Lei Chen, Chenglong Ge, Shanzhou Duan, Lichen Yin, Yongbing Chen
Publikováno v:
Biomaterials Science. 10:6258-6266
Apoptosis of cardiomyocytes is a critical outcome of myocardial ischemia-reperfusion injury (MIRI), which leads to the permanent impairment of cardiac function. Upregulated E2F1 is implicated in inducing cardiomyocyte apoptosis, and thus intervention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6dc9b6e5b1152fdf92c0a576e84e27d
https://doi.org/10.1039/d2bm01075e
https://doi.org/10.1039/d2bm01075e
Autor:
Yuansong Wei, Xudong Li, Juanhui Lin, Yang Zhou, Jiandong Yang, Mengying Hou, Fan Wu, Jing Yan, Chenglong Ge, Duanmin Hu, Lichen Yin
Publikováno v:
Advanced Materials. 35
Oral delivery of siRNA provides a promising paradigm for treating diseases that require regular injections. However, the multiple gastrointestinal and systemic barriers often lead to inefficient oral absorption and low bioavailability of siRNA. Techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fe87c0cd9b98e3473b2f801c2afe25
https://doi.org/10.1002/adma.202206821
https://doi.org/10.1002/adma.202206821
Autor:
Shanzhou Duan, Lichen Yin, Mengying Hou, Ziyin Zhao, Zhimin Zhang, Rongying Zhu, Xun Liu, Renxiang Zhou, Yonghua Sang
Publikováno v:
Biomaterials Science. 9:4639-4647
Cytosolic protein delivery holds great potential for the development of protein-based biotechnologies and therapeutics. Currently, cytosolic protein delivery is mainly achieved with the assistance of various carriers. Herein, we present a universal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befa2d3db819191a5c7e41dc27d11db2
https://doi.org/10.1039/d1bm00548k
https://doi.org/10.1039/d1bm00548k
Publikováno v:
Nano Research. 13:2706-2715
Insufficient intratumoral penetration greatly hurdles the anticancer performance of nanomedicine. To realize highly efficient tumor penetration in a precisely and spatiotemporally controlled manner, far-red light-responsive nanoclusters (NCs) capable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::584c35272db5547edfaea0fc0d4f35f8
https://doi.org/10.1007/s12274-020-2913-7
https://doi.org/10.1007/s12274-020-2913-7
Immuno-Engineered Nanodecoys for the Multi-Target Anti-Inflammatory Treatment of Autoimmune Diseases
Autor:
Mengying Hou, Yuansong Wei, Ziyin Zhao, Wenqing Han, Renxiang Zhou, Yang Zhou, Yiran Zheng, Lichen Yin
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 34(12)
Overactivated T cells and overproduced pro-inflammatory cytokines form a self-amplified signaling loop to continuously exacerbate the dysregulated inflammatory response and propel the progression of autoimmune diseases (AIDs). Herein, immuno-engineer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e621def1c9f2298c5726c6039abd77b
https://pubmed.ncbi.nlm.nih.gov/35044010
https://pubmed.ncbi.nlm.nih.gov/35044010
Autor:
Zhongmin Liu, Xiaozhong Zhou, Mengyuan Yin, Lichen Yin, Mengying Hou, Yang Zhou, Ziyin Zhao, Yekun Deng
Publikováno v:
Science Advances
Description
Biomimetic nanodecoys reconstruct the osteoclast/osteoblast balance to treat postmenopausal osteoporosis.
Imbalance between osteoblasts and osteoclasts accounts for the incidence and deterioration of postmenopausal osteoporosis.
Biomimetic nanodecoys reconstruct the osteoclast/osteoblast balance to treat postmenopausal osteoporosis.
Imbalance between osteoblasts and osteoclasts accounts for the incidence and deterioration of postmenopausal osteoporosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d2eaeb83679ff4354600801a467a89
https://doi.org/10.1126/sciadv.abl6432
https://doi.org/10.1126/sciadv.abl6432