Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mengyao Chai"'
Autor:
Haotian Zong, Yunshan Zhang, Xingxing Liu, Zhongyuan Xu, Jing Ye, Shasha Lu, Xinyu Guo, Zhihao Yang, Xiaoyu Zhang, Mengyao Chai, Minzhi Fan, Yuheng Liao, Wenjian Yang, Yue Wu, Diming Zhang
Publikováno v:
View, Vol 4, Iss 4, Pp n/a-n/a (2023)
Abstract Genetic testing plays an important role in human health management and disease prevention. However, traditional genetic testing methods have been unable to fulfill the current diagnostic needs owing to several limitations, including high cos
Externí odkaz:
https://doaj.org/article/786cdf726bfd424e8bf031b6e1eceef4
Autor:
Qing Ma, Yini Xiao, Wenjun Xu, Menghan Wang, Sheng Li, Zhihao Yang, Minglu Xu, Tengjiao Zhang, Zhen-Ning Zhang, Rui Hu, Qiang Su, Fei Yuan, Tinghui Xiao, Xuan Wang, Qing He, Jiaxu Zhao, Zheng-jun Chen, Zhejin Sheng, Mengyao Chai, Hong Wang, Weiyang Shi, Qiaolin Deng, Xin Cheng, Weida Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Immature function and fragility hinder application of hESC-derived β cells (SC-β cell) for diabetes cell therapy. Here, the authors identify ZnT8 as a gene editing target to enhance the insulin secretion and cell survival under metabolic stress by
Externí odkaz:
https://doaj.org/article/498f4e26b64740c4ac0e64e6b7a3344f
Autor:
Fei Yuan, Yana Li, Rui Hu, Mengting Gong, Mengyao Chai, Xuefei Ma, Jiaxue Cha, Pan Guo, Kaijiang Yang, Mushan Li, Minglu Xu, Qing Ma, Qiang Su, Chuan Zhang, Zhejin Sheng, Heng Wu, Yuan Wang, Wen Yuan, Shan Bian, Li Shao, Ru Zhang, Kaicheng Li, Zhen Shao, Zhen-Ning Zhang, Weida Li
Publikováno v:
Molecular Psychiatry. 28:1557-1570
Dysregulated neurite outgrowth and synapse formation underlie many psychiatric disorders, which are also manifested by wolfram syndrome (WS). Whether and how the causative gene WFS1 deficiency affects synapse formation remain elusive. By mirroring hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd47b3aae25841817eef9168f23e5395
https://doi.org/10.1038/s41380-023-01987-3
https://doi.org/10.1038/s41380-023-01987-3
Autor:
Qing Ma, Yini Xiao, Wenjun Xu, Menghan Wang, Sheng Li, Zhihao Yang, Minglu Xu, Tengjiao Zhang, Zhen-Ning Zhang, Rui Hu, Qiang Su, Fei Yuan, Tinghui Xiao, Xuan Wang, Qing He, Jiaxu Zhao, Zheng-jun Chen, Zhejin Sheng, Mengyao Chai, Hong Wang, Weiyang Shi, Qiaolin Deng, Xin Cheng, Weida Li
Publikováno v:
Nature communications. 13(1)
Human embryonic stem cell-derived β cells (SC-β cells) hold great promise for treatment of diabetes, yet how to achieve functional maturation and protect them against metabolic stresses such as glucotoxicity and lipotoxicity remains elusive. Our si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f632c51609427c3735fc6e35147c42f
https://pubmed.ncbi.nlm.nih.gov/35922574
https://pubmed.ncbi.nlm.nih.gov/35922574