Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mengxuan Chen"'
Autor:
Athena Y. Gong, Ying Jin Qiao, Mengxuan Chen, Zubia Alam, Deepak K. Malhotra, Lance Dworkin, Wenjun Ju, William T. Gunning
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ethyl carbamate (EC) is a process contaminant found in fermented foods and alcoholic beverages. Metabolic conversion of ethyl carbamate generates vinyl carbamate (VC), a carcinogenic metabolite. EC, as a Group 2A probable human carcinogen, and the mo
Externí odkaz:
https://doaj.org/article/94398cde3f994f248dc86b431cc97144
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103127- (2024)
Emerging evidence suggests that GSK3β, a redox-sensitive transducer downstream of insulin signaling, acts as a convergent point for myriad pathways implicated in kidney injury, repair, and regeneration. However, its role in diabetic kidney disease r
Externí odkaz:
https://doaj.org/article/dcac5c0d5b9644198b9ade1585478e72
Publikováno v:
Translation, Vol 11, Iss 3 (2023)
Background: Epidemiological evidence suggests that hyperinsulinemia or insulin resistance is a significant risk factor for the development of diabetic complications such as DKD. However, whether hyperinsulinemia per se plays a causative role in the d
Externí odkaz:
https://doaj.org/article/65373d7ccf7b49ad9224dd3950b82ab3
Publikováno v:
Translation, Vol 11, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/3866b8f9d6ab4cc383757690ce059802
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 15, Iss 11, Pp n/a-n/a (2023)
Abstract Modeling deep convection accurately in tropical regions is important. However, biases remain in current trigger functions. To alleviate the overestimation of frequency and wrong depiction of the diurnal cycle, we propose a deep convection tr
Externí odkaz:
https://doaj.org/article/6dd473549cf540bea6745bd19835ccf4
Publikováno v:
Annals of Hepatology, Vol 27, Iss 4, Pp 100700- (2022)
Objective: This study aimed to determine the roles of microRNA (miR)-122 in the activation of hepatic stellate cells (HSCs) and liver cirrhosis. Methods: Rat primary HSCs were incubated with transforming growth factor-beta (TGF-β), during which miR-
Externí odkaz:
https://doaj.org/article/6317058db7b246caa5890fbeaed245d0
Publikováno v:
Marine Drugs, Vol 17, Iss 5, p 292 (2019)
The marine-sourced fungus Penicillium sp. ZZ380 was previously reported to have the ability to produce a series of new pyrrospirone alkaloids. Further investigation on this strain resulted in the isolation and identification of novel penicipyrroether
Externí odkaz:
https://doaj.org/article/849851873ca5476d9718608aaa8e860a
Autor:
Gong, Athena Y., Ying Jin Qiao, Mengxuan Chen, Alam, Zubia, Malhotra, Deepak K., Dworkin, Lance, Wenjun Ju, Gunning, William T.
Publikováno v:
Frontiers in Pharmacology; 2024, p1-13, 13p
Publikováno v:
IEEE Transactions on Geoscience and Remote Sensing. 61:1-17
Publikováno v:
Journal of Physiology and Biochemistry. 78:885-895
Activated hepatic stellate cells (HSCs) are considered the major drivers in the process of hepatic fibrosis. This study intends to explore the mechanism underlying microRNA (miR)-34b-5p effects over liver fibrosis through the enhancer of zeste 2 (EZH