Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mengxin Cheng"'
Autor:
Jun Chen, Tao Wang, Xiaoou Li, Lijuan Gao, Ke Wang, Mengxin Cheng, Zijian Zeng, Lei Chen, Yongchun Shen, Fuqiang Wen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Chronic obstructive pulmonary disease (COPD) is characterised by persistent airway inflammation even after cigarette smoking cessation. Neutrophil extracellular traps (NETs) have been implicated in COPD severity and acute airway inflammation
Externí odkaz:
https://doaj.org/article/feced894e9804fcbb5c0df35394508aa
Autor:
Yuwei Liu, Li Peng, Jing Chen, Ling Chen, Ying Wu, Mengxin Cheng, Min Chen, Xujun Ye, Yalei Jin
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Post-transcriptional regulation plays a critical role in controlling biological processes such as aging. Previous studies have shown that eukaryotic initiation factor 5A (EIF5A) might play a crucial role in aging. It is unknown wh
Externí odkaz:
https://doaj.org/article/51e53d16a6044c7bb0aa17a3612dd71b
Autor:
Zijian Zeng, Mengxin Cheng, Meng Li, Tao Wang, Fuqiang Wen, Michael J. Sanderson, James Sneyd, Yongchun Shen, Jun Chen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
BALB/c and C57BL/6 mouse strains are widely used as animal model in studies of respiratory diseases, such as asthma. Asthma is characterized by airway hyperresponsiveness, which is eventually resulted from the excessive airway smooth muscle (ASM) con
Externí odkaz:
https://doaj.org/article/febcca5630c94857b017f7e4f52ca099
Autor:
Ke Wang, Youyu Wang, Yufang Cao, Hao Wang, Yongfang Zhou, Lijuan Gao, Zijian Zeng, Mengxin Cheng, Xiaodong Jin, Jun Chen, Fuqiang Wen, Tao Wang
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Fibroproliferative repair starts early in the inflammatory phase of acute respiratory distress syndrome (ARDS) and indicates a poor prognosis. Lumican, a small leucine-rich proteoglycan, is implicated in homeostasis and fibrogenes
Externí odkaz:
https://doaj.org/article/1eaf36c37ffb405ba454861d9bf84da9
Autor:
Li Peng, Yuwei Liu, Jing Chen, Mengxin Cheng, Ying Wu, Min Chen, Ya Zhong, Dan Shen, Ling Chen, Xujun Ye
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-10 (2022)
Abstract Background Aberrant alternative splicing (AS) contributes to tumor progression. Previous studies have shown that apurinic-apyrimidinic endonuclease-1 (APEX1) is involved in tumor progression. It is unknown whether APEX1 functions in tumor pr
Externí odkaz:
https://doaj.org/article/ad11a44a180f42059e749f3a8b7b90ed
Autor:
Lijuan Gao, Xiaoou Li, Hao Wang, Yue Liao, Yongfang Zhou, Ke Wang, Jun Hu, Mengxin Cheng, Zijian Zeng, Tao Wang, Fuqiang Wen
Publikováno v:
Journal of Intensive Care, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract Background Autotaxin (ATX) is a secreted glycoprotein that is widely present in extracellular biological fluids and has been implicated in many inflammatory and fibrotic diseases. However, the clinical impact of the release of ATX in patient
Externí odkaz:
https://doaj.org/article/8380396832594df2b76829bcbe777f11
Autor:
Diandian Li, Cheng Shen, Lian Liu, Jun Hu, Jiangyue Qin, Luqi Dai, Lijuan Gao, Mengxin Cheng, Dingran Wang, Rong Bao, Bo Wang
Publikováno v:
Toxicology. 477
Cigarette smoke (CS) mediates inflammation and epithelial-mesenchymal transition (EMT) in bronchial epithelial cells, contributing to airway remodeling in chronic obstructive pulmonary disease (COPD). Cross-talk between metabolic pathways and cell si
Autor:
Ke Wang, Yue Liao, Xiaoou Li, Ran Wang, Zijian Zeng, Mengxin Cheng, Lijuan Gao, Dan Xu, Fuqiang Wen, Tao Wang, Jun Chen
Publikováno v:
International Immunopharmacology. 114:109537
Chronic obstructive pulmonary disease (COPD) is an important public health challenge worldwide, and is usually caused by significant exposure to noxious agents, particularly cigarette smoke. Recent studies have revealed that excessive production of n
Autor:
Jun Hu, Yongfang Zhou, Mengxin Cheng, Zijian Zeng, Xiaoou Li, Hao Wang, Ke Wang, Tao Wang, Fuqiang Wen, Yue Liao, Lijuan Gao
Publikováno v:
Journal of Intensive Care
Journal of Intensive Care, Vol 9, Iss 1, Pp 1-11 (2021)
Journal of Intensive Care, Vol 9, Iss 1, Pp 1-11 (2021)
Background Autotaxin (ATX) is a secreted glycoprotein that is widely present in extracellular biological fluids and has been implicated in many inflammatory and fibrotic diseases. However, the clinical impact of the release of ATX in patients with ac
Autor:
Fuqiang Wen, Hao Wang, Xianghu Zeng, Yufang Cao, Jun Hu, Zijian Zeng, Lian Liu, Tao Wang, Mengxin Cheng, Ke Wang, Lijuan Gao
Publikováno v:
Shock (Augusta, Ga.). 56(3)
BACKGROUND Angiopoietin-like 4 (ANGPTL4) is a secreted glycoprotein that plays an important role in endothelial injury and the inflammatory response. Experimental models have implicated ANGPTL4 in acute respiratory distress syndrome (ARDS), but its i