Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mengxiang Tian"'
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
The innate immune system plays a vital role in the inflammatory process, serving as a crucial mechanism for the body to respond to infection, cellular stress, and tissue damage. The cGAS-STING signaling pathway is pivotal in the onset and progression
Externí odkaz:
https://doaj.org/article/f8f8475d053c41aa86593bf3de98a107
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Cancer immunotherapy has emerged as a pivotal approach for treating various types of cancer, incorporating strategies such as chimeric antigen receptor T-cell (CAR-T) therapy, immune checkpoint blockade therapy, neoantigen peptides, mRNA vaccines, an
Externí odkaz:
https://doaj.org/article/f02a7d2fd8df4c07a27e9eb0496148a4
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1339 (2024)
The growing global prevalence of chronic diseases has highlighted the limitations of conventional drug delivery methods, which often suffer from non-specific distribution, systemic toxicity, and poor bioavailability. Microscale and nanoscale material
Externí odkaz:
https://doaj.org/article/9c761d3c1ced467ab8b46fdf2c8de95e
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1728 (2024)
The innate immune system is the body’s natural defense system, which recognizes a wide range of microbial molecules (such as bacterial DNA and RNA) and abnormal molecules within cells (such as misplaced DNA, self-antigens) to play its role. DNA rel
Externí odkaz:
https://doaj.org/article/fecc3ab612354f078dc52d1210e2150c
Autor:
Xitao Wang, Wei Cheng, Xiaolin Dou, Fengbo Tan, Shipeng Yan, Zhongyi Zhou, Yuqiang Li, Biaoxiang Xu, Chongshun Liu, Heming Ge, Mengxiang Tian, Fangchun Liu, Liling Li, Sai Zhang, Qingling Li, Haiping Pei, Qian Pei
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 2538-2550 (2023)
Abstract Objective Despite controversy over its origin and definition, the significance of tumour deposit (TD) has been underestimated in the tumour node metastasis (TNM) staging system for colon cancer, especially in stage III patients. We aimed to
Externí odkaz:
https://doaj.org/article/9efaead14e1041cea5fdec0aa6385152
Publikováno v:
Journal of Investigative Surgery, Vol 35, Iss 4, Pp 850-859 (2022)
Introduction: The prognostic role of the N1c remains unclear in colorectal cancer (CRC). Our study aimed to determine the prognostic value of N1c. Methods: Patients diagnosed in 2010-2015 were accessed from the Surveillance, Epidemiology, and End Res
Externí odkaz:
https://doaj.org/article/96101b11d61046159f9982fc2357f2db
Autor:
Yuan Zhou, Zhengda Pei, Aizezi Maimaiti, Linyi Zheng, Zhongcheng Zhu, Mengxiang Tian, Zhongyi Zhou, Fengbo Tan, Qian Pei, Yuqiang Li, Wenxue Liu
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract N6-methyladenosine (m6A) modifications of RNAs are involved in various aspects of colorectal carcinogenesis via regulation of mRNA stability, splicing, and translation. KIAA1429, an m6A methyltransferase, was found deregulated in multiple ca
Externí odkaz:
https://doaj.org/article/26cbc8c0a31c4127b48d7210cd8091a2
Autor:
Dan Wang, Heming Ge, Mengxiang Tian, Chenglong Li, Lilan Zhao, Qian Pei, Fengbo Tan, Yuqiang Li, Chen Ling, Cenap Güngör
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundIt remains controversial whether radiotherapy (RT) improves survival in patients with stage IIB/III PDAC. A growing number of studies have found that patients’ age at diagnosis and tumor site not only affect prognosis, but also may lead t
Externí odkaz:
https://doaj.org/article/61ed1af8a7ab4c93b1874f447daa6b51
Autor:
Yuqiang Li, Mengxiang Tian, Wenxue Liu, Dan Wang, Zhongyi Zhou, Qian Pei, Yan Huang, Fengbo Tan, Cenap Güngör
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Previous studies reported that Follistatin-like 3 (FSTL3) is abundantly expressed in several solid tumors and participate in the regulation of cell metabolism. However, the clinico-pathological significance, biological role and molecular mechanism of
Externí odkaz:
https://doaj.org/article/bec2c70936d84717952253d737e6e006
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
In recent years, in-depth studies have shown that extracellular matrix stiffness plays an important role in cell growth, proliferation, migration, immunity, malignant transformation, and apoptosis. Most of these processes entail metabolic reprogrammi
Externí odkaz:
https://doaj.org/article/25b72040efec4746aae0c54483538802