Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mengtong Duan"'
Autor:
Matthew L Schwartz, Daniel P Nickerson, Braden T Lobingier, Rachael L Plemel, Mengtong Duan, Cortney G Angers, Michael Zick, Alexey J Merz
Publikováno v:
eLife, Vol 6 (2017)
Zippering of SNARE complexes spanning docked membranes is essential for most intracellular fusion events. Here, we explore how SNARE regulators operate on discrete zippering states. The formation of a metastable trans-complex, catalyzed by HOPS and i
Externí odkaz:
https://doaj.org/article/0baf4a25cfe943f89e532ac2f3d2c013
Publikováno v:
eLife, Vol 6 (2017)
At physiological protein levels, the slow HOPS- and SNARE-dependent fusion which occurs upon complete SNARE zippering is stimulated by Sec17 and Sec18:ATP without requiring ATP hydrolysis. To stimulate, Sec17 needs its central residues which bind the
Externí odkaz:
https://doaj.org/article/fa380fd6b0cf429fbdcfa5fab9ea62c7
Autor:
Mengtong Duan1, Guanbin Gao2, Lin, Ariel1, Mackey, Emma J.1, Banfield, David K.2, Merz, Alexey J.1 merza@uw.edu
Publikováno v:
Journal of Cell Biology. 6/3/2024, Vol. 223 Issue 6, p1-S8. 23p.
Autor:
Mengtong Duan1, Plemel, Rachael L.1, Tomoka Takenaka2, Lin, Ariel1,3, Delgado, Beatriz Marie3, Nattermann, Una1,4,5, Nickerson, Daniel P.3, Joji Mima6, Miller, Elizabeth A.7, Merz, Alexey J.1 merza@uw.edu
Publikováno v:
Journal of Cell Biology. 6/3/2024, Vol. 223 Issue 6, p1-S4. 23p.
Applications of mammalian synthetic biology increasingly require the ability to express multiple proteins at user-determined stoichiometries from single, compactly encoded transcripts. Here we present an approach for expressing multiple open reading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aaa67dd68a07bebb1c0ff382971fc7b
https://doi.org/10.1101/2023.05.26.541240
https://doi.org/10.1101/2023.05.26.541240
Autor:
Di Wu, Diego Baresch, Colin Cook, Zhichao Ma, Mengtong Duan, Dina Malounda, David Maresca, Maria P. Abundo, Justin Lee, Shirin Shivaei, David R. Mittelstein, Tian Qiu, Peer Fischer, Mikhail G. Shapiro
Publikováno v:
Science Advances
The ability to physically manipulate specific cells is critical for the fields of biomedicine, synthetic biology, and living materials. Ultrasound has the ability to manipulate cells with high spatiotemporal precision via acoustic radiation force (AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f81b91bcc2102986cfcc61cf7aa639
https://doi.org/10.1126/sciadv.add9186
https://doi.org/10.1126/sciadv.add9186
Autor:
Robert C. Hurt, Marjorie T. Buss, Mengtong Duan, Katie Wong, Mei Yi You, Daniel P. Sawyer, Margaret B. Swift, Przemysław Dutka, Pierina Barturen-Larrea, David R. Mittelstein, Zhiyang Jin, Mohamad H. Abedi, Arash Farhadi, Ramya Deshpande, Mikhail G. Shapiro
Publikováno v:
Nature Biotechnology.
Ultrasound allows imaging at a much greater depth than optical methods, but existing genetically encoded acoustic reporters for in vivo cellular imaging have been limited by poor sensitivity, specificity and in vivo expression. Here we describe two a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::736381010f242442cc50cd50d613835b
https://doi.org/10.1038/s41587-022-01581-y
https://doi.org/10.1038/s41587-022-01581-y
Autor:
Robert C. Hurt, Marjorie T. Buss, Mengtong Duan, Katie Wong, Mei Yi You, Daniel P. Sawyer, Margaret B. Swift, Przemysław Dutka, Pierina Barturen-Larrea, David R. Mittelstein, Zhiyang Jin, Mohamad H. Abedi, Arash Farhadi, Ramya Deshpande, Mikhail G. Shapiro
A major outstanding challenge in the fields of biological research, synthetic biology and cell-based medicine is visualizing the function of natural and engineered cells noninvasively inside opaque organisms. Ultrasound imaging has the potential to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9db48bd78a8c979d2f343077b291488c
https://doi.org/10.1101/2021.04.26.441537
https://doi.org/10.1101/2021.04.26.441537
Gatekeeper helix activates Golgi SM protein Sly1 and directly mediates close-range vesicle tethering
Autor:
B. M. Delgado, Rachael L. Plemel, Joji Mima, Una Nattermann, Mengtong Duan, Elizabeth A. Miller, Alexey J. Merz, Daniel P. Nickerson, T. Takenaka, A. Lin
The essential Golgi protein Sly1 is a member of the SM (Sec1/mammalian Unc-18) family of SNARE chaperones. Sly1 was originally identified through gain-of-function alleles that bypass requirements for diverse vesicle tethering factors. Employing genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a634574df040a47f697b8a5d5d9717
Autor:
Michael Zick, Alexey J. Merz, Rachael L. Plemel, Matthew L. Schwartz, Cortney G. Angers, Mengtong Duan, Braden T. Lobingier, Daniel P. Nickerson
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Zippering of SNARE complexes spanning docked membranes is essential for most intracellular fusion events. Here, we explore how SNARE regulators operate on discrete zippering states. The formation of a metastable trans-complex, catalyzed by HOPS and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51584c74560d63fc65018401a1f569fb
http://europepmc.org/articles/PMC5643095
http://europepmc.org/articles/PMC5643095