Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mengsha Tong"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2049-2056 (2024)
Multi-omics technologies, encompassing genomics, proteomics, and transcriptomics, provide profound insights into cancer biology. A fundamental computational approach for analyzing multi-omics data is differential analysis, which identifies molecular
Externí odkaz:
https://doaj.org/article/647efc60b8b44e57b892665d37e7c503
Autor:
Shaoqian Ma, Gezhi Xiao, Xusheng Deng, Mengsha Tong, Jialiang Huang, Qingge Li, Yongyou Zhang
Publikováno v:
Viruses, Vol 15, Iss 10, p 2017 (2023)
The coronavirus disease 2019 (COVID-19) pandemic is still ongoing, with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continuing to evolve and accumulate mutations. While various bioinformatics tools have been developed for SARS-CoV-2,
Externí odkaz:
https://doaj.org/article/1cf4de18eb85499b848adf0ff66ad6fc
Autor:
Mengsha Tong, Chunyu Yu, Jinwen Shi, Wenwen Huang, Sai Ge, Mingwei Liu, Lei Song, Dongdong Zhan, Xia Xia, Wanlin Liu, Jinwen Feng, Wenhao Shi, Jiafu Ji, Jing Gao, Tieliu Shi, Weimin Zhu, Chen Ding, Yi Wang, Fuchu He, Lin Shen, Tingting Li, Jun Qin
Publikováno v:
iScience, Vol 22, Iss , Pp 44-57 (2019)
Summary: The diffuse-type gastric cancer (DGC) constitutes a subgroup of gastric cancer with poor prognosis and no effective molecular therapies. Here, we report a phosphoproteomic landscape of DGC derived from 83 tumors together with their nearby ti
Externí odkaz:
https://doaj.org/article/b7103be92c014dd6907031f7ecb7c579
Autor:
Mengsha Tong, Chunyu Yu, Dongdong Zhan, Ming Zhang, Bei Zhen, Weimin Zhu, Yi Wang, Congying Wu, Fuchu He, Jun Qin, Tingting Li
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 305-317 (2019)
Background: Molecular subtyping of cancer aimed to predict patient overall survival (OS) and nominate drug targets for patient treatments is central to precision oncology. Owing to the rapid development of phosphoproteomics, we can now measure thousa
Externí odkaz:
https://doaj.org/article/f719f69a89954d8cbb5c2c9ceb7bc684
Autor:
Mengsha Tong, Yuxiang Lin, Wenxian Yang, Jinsheng Song, Zheyang Zhang, Jiajing Xie, Jingyi Tian, Shijie Luo, Chenyu Liang, Jialiang Huang, Rongshan Yu
Publikováno v:
Briefings in Bioinformatics. 24
Colorectal cancer (CRC) is one of the most common gastrointestinal malignancies. There are few recurrence risk signatures for CRC patients. Single-cell RNA-sequencing (scRNA-seq) provides a high resolution platform for prognostic signature detection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48a5a6de6e4e67efbc76168e0607e91
https://doi.org/10.1093/bib/bbad078
https://doi.org/10.1093/bib/bbad078
Autor:
Danni Hong, Hongli Lin, Lifang Liu, Muya Shu, Jianwu Dai, Falong Lu, Mengsha Tong, Jialiang Huang
Publikováno v:
Briefings in Bioinformatics. 24
Many enhancers exist as clusters in the genome and control cell identity and disease genes; however, the underlying mechanism remains largely unknown. Here, we introduce an algorithm, eNet, to build enhancer networks by integrating single-cell chroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe9111c75c2f1ed3d9addee8fc3a631
https://doi.org/10.1093/bib/bbac508
https://doi.org/10.1093/bib/bbac508
Autor:
Mengsha Tong, Shijie Luo, Lin Gu, Zheyang Zhang, Chenyu Liang, Jingyi Tian, Huaqiang Huang, Yuxiang Lin, Jialiang Huang
Background & AimsLiver cancer is one of the most leading causes of cancer deaths. Cirrhosis is an important risk factor for liver cancer, which is the result of over-fibrosis caused by diffuse and long-term liver damage. Despite extensive research, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f24bbbbf293981f83527d38a1d2019a7
https://doi.org/10.1101/2022.11.03.515124
https://doi.org/10.1101/2022.11.03.515124
Autor:
Jinwen Shi, Wenhao Shi, Lin Shen, Wenwen Huang, Yi Wang, Mingwei Liu, Fuchu He, Sai Ge, Jinwen Feng, Wanlin Liu, Xia Xia, Tieliu Shi, Jun Qin, Mengsha Tong, Chunyu Yu, Jiafu Ji, Tingting Li, Chen Ding, Lei Song, Jing Gao, Weimin Zhu, Dongdong Zhan
Publikováno v:
iScience, Vol 22, Iss, Pp 44-57 (2019)
iScience
iScience
Summary The diffuse-type gastric cancer (DGC) constitutes a subgroup of gastric cancer with poor prognosis and no effective molecular therapies. Here, we report a phosphoproteomic landscape of DGC derived from 83 tumors together with their nearby tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8067beca51e24062e4fd83dfc5e10b1d
https://doi.org/10.1016/j.isci.2019.11.003
https://doi.org/10.1016/j.isci.2019.11.003
Autor:
Conglin Ren, Mingshuang Li, Yang Zheng, Bingbing Cai, Weibin Du, Helou Zhang, Fengqing Wu, Mengsha Tong, Fu Lin, Jinfu Wang, Renfu Quan
Publikováno v:
Journal of cellular and molecular medicine. 26(4)
Ankylosing spondylitis (AS) is an autoimmune disease with unknown aetiology. To unravel the mechanisms mediating AS pathogenesis, we profiled peripheral blood mononuclear cells (PBMCs) from AS patients and healthy subjects using 10X single-cell RNA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9832873b81463162172ec1de4f48b89d
https://pubmed.ncbi.nlm.nih.gov/34994057
https://pubmed.ncbi.nlm.nih.gov/34994057
Autor:
Chunyu Yu, Congying Wu, Dongdong Zhan, Bei Zhen, Ming Zhang, Weimin Zhu, Jun Qin, Yi Wang, Tingting Li, Mengsha Tong, Fuchu He
Publikováno v:
EBioMedicine
Background Molecular subtyping of cancer aimed to predict patient overall survival (OS) and nominate drug targets for patient treatments is central to precision oncology. Owing to the rapid development of phosphoproteomics, we can now measure thousan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633fcf513f0f3ffb3b4b1bb7dee2d9be
https://doi.org/10.1016/j.ebiom.2018.12.039
https://doi.org/10.1016/j.ebiom.2018.12.039