Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Mengru Cao"'
Autor:
Weina Fan, Ying Xing, Shi Yan, Wei Liu, Jinfeng Ning, Fanglin Tian, Xin Wang, Yuning Zhan, Lixin Luo, Mengru Cao, Jian Huang, Li Cai
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background Lung adenocarcinoma (LUAD) patients have a dismal survival rate because of cancer metastasis and drug resistance. The study aims to identify the genes that concurrently modulate EMT, metastasis and EGFR-TKI resistance, and to inve
Externí odkaz:
https://doaj.org/article/aeee91a5a9284ceca2e6632d57eec117
Publikováno v:
Annals of Medicine, Vol 55, Iss 2 (2023)
AbstractBackground Endoplasmic reticulum stress (ERs) is an important cellular self-defence mechanism, which is closely related to tumorigenesis and development. However, the role of endoplasmic reticulum stress state in the development of lung adeno
Externí odkaz:
https://doaj.org/article/c622adc0bb9c41d8860ebd633fc7426a
Autor:
Mengru Cao, Hailing Lu, Shi Yan, Hui Pang, Lichun Sun, Chunhong Li, Xuesong Chen, Wei Liu, Jing Hu, Jian Huang, Ying Xing, Ningzhi Zhang, Yingqi Chen, Ting He, Danni Zhao, Yuanyuan Sun, Lin Zhao, Xiaomeng Liu, Li Cai
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Treatment options for pretreated triple-negative breast cancer (TNBC) are limited. This study aimed to evaluate the efficacy and safety of apatinib, an antiangiogenic agent, in combination of etoposide for pretreated patients with
Externí odkaz:
https://doaj.org/article/fb54b14704f0492e8e2b35bf4cc390f1
Autor:
Jingtong Zhai, Xiaoying Sun, Fang Zhao, Bo Pan, Huihui Li, Zheng Lv, Mengru Cao, Jiuda Zhao, Hongnan Mo, Fei Ma, Binghe Xu
Publikováno v:
Breast, Vol 67, Iss , Pp 36-45 (2023)
Background: Taxane-induced peripheral neuropathy (TIPN) is a debilitating adverse effect of cancer treatments with taxanes which may require a reduction or discontinuation chemotherapy and affect clinical and survival outcomes. A number of factors ha
Externí odkaz:
https://doaj.org/article/24f0aa53d02e445b8759fd1e081258f8
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The role of long non-coding RNA (lncRNA) in human tumors has gradually received increasing attention in recent years. Particularly, the different functions of lncRNAs in different subcellular localizations have been widely investigated. The upregulat
Externí odkaz:
https://doaj.org/article/1ee4732f29114421a92831193e5f9086
Autor:
Yuechao Liu, Yang Song, Mengru Cao, Weina Fan, Yaowen Cui, Yimeng Cui, Yuning Zhan, Ruixue Gu, Fanglin Tian, Shuai Zhang, Li Cai, Ying Xing
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 4, Pp n/a-n/a (2022)
Abstract Background There is growing evidence that endocytosis plays a pivotal role in cancer metastasis. In this study, we first identified endocytic and metastasis‐associated genes (EMGs) and then investigated the biological functions and mechani
Externí odkaz:
https://doaj.org/article/57043908a94d43278dbd9ac670695914
Autor:
Dexin Jia, Ying Xing, Yuning Zhan, Mengru Cao, Fanglin Tian, Weina Fan, Jian Huang, Yimeng Cui, Ruixue Gu, Yaowen Cui, Yuechao Liu, Shuai Zhang, Li Cai, Xiaomei Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Non-small-cell lung carcinoma (NSCLC) is considered to be a fatal disease and characterized by a poor prognosis. Long non-coding RNAs (lncRNAs) have been reported to act as biomarkers and therapeutic targets in solid tumors. However, the expression o
Externí odkaz:
https://doaj.org/article/ffb50526da4f421b899b300def9128f2
Autor:
Yang Song, Shi Yan, Weina Fan, Mengyan Zhang, Wei Liu, Hailing Lu, Mengru Cao, Chenguang Hao, Lin Chen, Fanglin Tian, Yuning Zhan, Li Cai, Ying Xing
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Lung adenocarcinoma (LUAD) is a devastating disease with poor patient survival. Cancer immunotherapy has revolutionized the treatment of LUAD, but only a limited number of patients effectively respond to this treatment. Thus, the work to elucidate th
Externí odkaz:
https://doaj.org/article/9c8e45b527574591be3f56c334b544e9
Autor:
Ying Xing, Yuechao Liu, Tianbo Liu, Qingwei Meng, Hailing Lu, Wei Liu, Jing Hu, Chunhong Li, Mengru Cao, Shi Yan, Jian Huang, Ting Wang, Li Cai
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Background The highly refractory nature of non-small cell lung cancer (NSCLC) to chemotherapeutic drugs is an important factor resulting in its poor prognosis. Recent studies have revealed that tumour necrosis factor alpha-induced protein 8
Externí odkaz:
https://doaj.org/article/076cccba61c8430aa7219e583e847b62
Autor:
Liang Cao, Nuzhat Shehla, Shumaila Tasneem, Mengru Cao, Wenbing Sheng, Yuqing Jian, Bin Li, Caiyun Peng, M. Iqbal Choudhary, Atta-ur-Rahman, Duan-fang Liao, Wei Wang
Publikováno v:
Molecules, Vol 24, Iss 9, p 1664 (2019)
As part of our continual efforts to exploit ‘Tujia Ethnomedicine’ for their pharmacophoric functionalities, we herein investigated Kadsura heteroclita collected from a deep Wulin mountain area in northern Hunan province. The current study resulte
Externí odkaz:
https://doaj.org/article/64675798346c4c4695a61125d7847842