Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mengru Bai"'
Publikováno v:
PeerJ, Vol 12, p e17806 (2024)
Epidermal growth factor (EGF) protein is a crucial biomolecule involved in regulating cell growth, proliferation, migration and differentiation, which is used in various therapeutic applications, such as wound healing and tissue regeneration. The pro
Externí odkaz:
https://doaj.org/article/c2ef060d6f0a4033aecc36359a0f7f96
Publikováno v:
PeerJ, Vol 11, p e15736 (2023)
After myocardial injury, cardiac fibroblasts (CFs) differentiate into myofibroblasts, which express and secrete extracellular matrix (ECM) components for myocardial repair, but also promote myocardial fibrosis. Recombinant fibroblast growth factor 2
Externí odkaz:
https://doaj.org/article/80adbd67345b49cab1226e125c736fc3
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundsPyroptosis, a newly pattern of specific programmed cell death, has been reported to participate in several cancers. However, the value of pyroptosis in breast cancer (BRCA) is still not clear.MethodsHerein, we analyzed the data of BRCA fro
Externí odkaz:
https://doaj.org/article/144cff43ae5546f3b4cefeb4d5f49a8c
Autor:
Mingyang, Chen, Mengru, Bai, Yaodong, Yi, Shuanghui, Lu, Jun, Luo, Ping, Li, Hengbin, Zhang, Huidi, Jiang, Hui, Zhou
Publikováno v:
Toxicology Letters. 363:1-10
Glucocorticoids such as dexamethasone (DEX) are widely prescribed to treat numerous conditions and diseases. However, glucocorticoid-induced liver lipid metabolism disorder, even nonalcoholic fatty liver disease, has caused extensive attention. Since
Publikováno v:
BioMed Research International. 2022:1-15
Background. To investigate the association between interleukins (IL-1β, IL-2, IL-4, IL-6, IL-8, and IL-10) and the disease severity of coronavirus disease 2019 (COVID-19). Materials and Methods. We systematically searched records investigating the r
Autor:
Mengru Bai, Mingyang Chen, Qingquan Zeng, Shuanghui Lu, Ping Li, Zhiyuan Ma, Nengming Lin, Caihong Zheng, Hui Zhou, Su Zeng, Dongli Sun, Huidi Jiang
Publikováno v:
British journal of pharmacologyREFERENCES. 179(17)
Plasma triglyceride (TG) levels increase as gestation proceeds, and abnormal elevation of TG increases the risk of pregnancy complications. The current study explored the mechanisms involved in hypertriglyceridaemia during pregnancy.Lipid profile and
Publikováno v:
BioMed research international. 2022
To investigate the association between interleukins (IL-1We systematically searched records investigating the role of interleukins (IL-1In total, 61 studies enrolled 14,136 subjects (14,041 patients and 95 healthy subjects) were enrolled in this meta
Autor:
Caihong Zheng, Qingquan Zeng, Huidi Jiang, Ping Li, Yingchun Chen, Zhiyuan Ma, Su Zeng, Hui Zhou, Mengru Bai, Dongli Sun, Mingyang Chen
Publikováno v:
Drug Metabolism and Disposition. 47:582-591
l-Carnitine (l-Car) plays a crucial role in fatty acid β-oxidation. However, the plasma l-Car concentration in women markedly declines during pregnancy, but the underlying mechanism and its consequences on maternal hepatic β-oxidation have not yet
Publikováno v:
Biopharmaceutics & Drug Disposition. 38:526-534
Sulpiride, a selective dopamine D2 receptor blocker, is used widely for the treatment of schizophrenia, depression and gastric/duodenal ulcers. Because the great majority of sulpiride is positively charged at physiological pH 7.4, and ~70% of the dos
Autor:
Caihong Zheng, Huidi Jiang, Mengru Bai, Dongli Sun, Yayun Weng, Ting Jiang, Zhiyuan Ma, Xi Yang
Publikováno v:
Archives of Toxicology. 91:3873-3884
Sulpiride is a typical antipsychotic drug for the treatment of schizophrenia, depression and other psychological disorders. It has been proven that a small amount of sulpiride could cross the human placenta using an ex vivo placental perfusion model.