Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mengqiu Miao"'
Autor:
Mengqiu Wu, Qianqian Jin, Xinyue Xu, Jiaojiao Fan, Weiyi Chen, Mengqiu Miao, Ran Gu, Shengnan Zhang, Yan Guo, Songming Huang, Yue Zhang, Aihua Zhang, Zhanjun Jia
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Renal fibrosis is a common characteristic of various chronic kidney diseases (CKDs) driving the loss of renal function. During this pathological process, persistent injury to renal tubular epithelial cells and activation of fibroblasts chief
Externí odkaz:
https://doaj.org/article/6060646513964417864527760b606ba0
Autor:
Mi Bai, Mengqiu Wu, Mingzhu Jiang, Jia He, Xu Deng, Shuang Xu, Jiaojiao Fan, Mengqiu Miao, Ting Wang, Yuting Li, Xiaowen Yu, Lin Wang, Yue Zhang, Songming Huang, Li Yang, Zhanjun Jia, Aihua Zhang
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp 1-22 (2023)
Abstract Mitochondria comprise the central metabolic hub of cells and their imbalance plays a pathogenic role in chronic kidney disease (CKD). Here, we studied Lon protease 1 (LONP1), a major mitochondrial protease, as its role in CKD pathogenesis is
Externí odkaz:
https://doaj.org/article/53d49939a7af46fba73c8a251f9bfa71
Publikováno v:
Kidney Diseases, Pp 1-1 (2023)
Background: Renal diseases remain an increasing public health issue affecting millions of people. The kidney is a highly energetic organ that is rich in mitochondria. Numerous studies have demonstrated the important role of mitochondria in maintainin
Externí odkaz:
https://doaj.org/article/18b7df7b06f14bd19bb3bc4444f2281e
Autor:
Mengqiu Miao, Mengqiu Wu, Yuting Li, Lingge Zhang, Qianqian Jin, Jiaojiao Fan, Xinyue Xu, Ran Gu, Haiping Hao, Aihua Zhang, Zhanjun Jia
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Hypoxia inducible factors (HIFs) and their regulatory hydroxylases the prolyl hydroxylase domain enzymes (PHDs) are the key mediators of the cellular response to hypoxia. HIFs are normally hydroxylated by PHDs and degraded, while under hypoxia, PHDs
Externí odkaz:
https://doaj.org/article/c2a096005a2e4107870d1a9d57878851
Autor:
Jiaojiao Fan, Xinyue Xu, Yuting Li, Lingge Zhang, Mengqiu Miao, Yujia Niu, Yue Zhang, Aihua Zhang, Zhanjun Jia, Mengqiu Wu
Publikováno v:
Free Radical Biology and Medicine. 194:84-98
Cisplatin is one of the most effective chemotherapy drugs and is widely used for cancer treatment. However, its clinical use is limited by nephrotoxicity. Emerging findings suggested that both ferroptosis and mitochondrial dysfunction mediate cisplat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9122947fe89c04524ae83cab60daef
https://doi.org/10.1016/j.freeradbiomed.2022.11.029
https://doi.org/10.1016/j.freeradbiomed.2022.11.029
Autor:
Mi Bai, Mengqiu Wu, Mingzhu Jiang, Jia He, Xu Deng, Shuang Xu, Jiaojiao Fan, Mengqiu Miao, Ting Wang, Yuting Li, Xiaowen Yu, Lin Wang, Yue Zhang, Songming Huang, Li Yang, Zhanjun Jia, Aihua Zhang
Publikováno v:
EMBO Molecular Medicine. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71294a8e2b41c815c5a9ebd1ee83ae5a
https://doi.org/10.15252/emmm.202216581
https://doi.org/10.15252/emmm.202216581
Autor:
Mengqiu Miao, Mengqiu Wu, Yuting Li, Lingge Zhang, Qianqian Jin, Jiaojiao Fan, Xinyue Xu, Ran Gu, Haiping Hao, Aihua Zhang, Zhanjun Jia
Publikováno v:
Frontiers in pharmacology. 13
Hypoxia inducible factors (HIFs) and their regulatory hydroxylases the prolyl hydroxylase domain enzymes (PHDs) are the key mediators of the cellular response to hypoxia. HIFs are normally hydroxylated by PHDs and degraded, while under hypoxia, PHDs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7897ecdb9c313ce8dd663cd0eb99fda
https://pubmed.ncbi.nlm.nih.gov/35281917
https://pubmed.ncbi.nlm.nih.gov/35281917
Autor:
Mengqiu Wu, Weiyi Chen, Mengqiu Miao, Qianqian Jin, Shengnan Zhang, Mi Bai, Jiaojiao Fan, Yue Zhang, Zhanjun Jia, Songming Huang
Publikováno v:
Clinical Science; Jul2021, Vol. 135 Issue 14, p1707-1726, 20p