Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Mengqin Yuan"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundGastric cancer (GC) ranks as the fifth most prevalent cancer globally, and its pronounced invasiveness and propensity to spread provide significant challenges for therapy. At present, there are no efficacious medications available for the t
Externí odkaz:
https://doaj.org/article/31c5f8e26a1e44149b35f7c4d3d2b791
Autor:
Fangfang Dai, Hua Liu, Juan He, Jinglin Wu, Chaoyan Yuan, Ruiqi Wang, Mengqin Yuan, Dongyong Yang, Zhimin Deng, Linlin Wang, Yanqing Wang, Xiao Yang, Huiling Wang, Wei Hu, Yanxiang Cheng
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Clinically, hormone replacement therapy (HRT) is the main treatment for primary ovarian insufficiency (POI). However, HRT may increase the risk of both breast cancer and cardiovascular disease. Exosomes derived from human umbilica
Externí odkaz:
https://doaj.org/article/fda5067c9a9449608b53d91a670df552
Hypertension and NAFLD risk: Insights from the NHANES 2017-2018 and Mendelian randomization analyses
Autor:
Mengqin Yuan, Jian He, Xue Hu, Lichao Yao, Ping Chen, Zheng Wang, Pingji Liu, Zhiyu Xiong, Yingan Jiang, Lanjuan Li, Jinjiao Li, Yuanyuan Ji
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 4, Pp 457-464 (2024)
Abstract. Background:. Hypertension and non-alcoholic fatty liver disease (NAFLD) share several pathophysiologic risk factors, and the exact relationship between the two remains unclear. Our study aims to provide evidence concerning the relationship
Externí odkaz:
https://doaj.org/article/88c1dd880985471a98209271cd9d6079
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101115- (2024)
The liver is an important metabolic and detoxification organ and hence demands a large amount of energy, which is mainly produced by the mitochondria. Liver tissues of patients with alcohol-related or non-alcohol-related liver diseases contain ultras
Externí odkaz:
https://doaj.org/article/127f1236883e4ca18127bcd82eeb8cea
Autor:
Shaoqi Yang, Yuheng Sun, Min Long, Xinbei Zhou, Mengqin Yuan, Liliang Yang, Wei Luo, Yusi Cheng, Xinxin Zhang, Wei Jiang, Jie Chao
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Chronic exposure to silica can lead to silicosis, one of the most serious occupational lung diseases worldwide, for which there is a lack of effective therapeutic drugs and tools. Epithelial mesenchymal transition plays an important role in
Externí odkaz:
https://doaj.org/article/a7e767e749be42eba7676d67f3f1f80b
Autor:
Ping Chen, Mengqin Yuan, Lichao Yao, Zhiyu Xiong, Pingji Liu, Zheng Wang, Yingan Jiang, Lanjuan Li
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116133- (2024)
Chronic Liver fibrosis may progress to liver cirrhosis and hepatocellular carcinoma (HCC), hence cause a substantial global burden. However, effective therapies for blocking fibrosis are still lacking. Although mesenchymal stem cells (MSCs) have been
Externí odkaz:
https://doaj.org/article/674206f945a3478cbe527261a83c493a
Autor:
Jing Wang, Xinxin Zhang, Min Long, Mengqin Yuan, Juan Yin, Wei Luo, Sha Wang, Yu Cai, Wei Jiang, Jie Chao
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Macrophage-derived glycoprotein nonmetastatic melanoma protein B (GPNMB) is trapped by fibrotic extracellular matrix in a pulmonary fibrosis model and may activate resident normal fibroblasts, promoting fibrosis.
Externí odkaz:
https://doaj.org/article/a399d74044de430cb843eed4aa802fc8
Autor:
Haizhou Liu, Mengqin Yuan, Ramkrishna Mitra, Xu Zhou, Min Long, Wanyue Lei, Shunheng Zhou, Yu-e Huang, Fei Hou, Christine M. Eischen, Wei Jiang
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-20 (2022)
Abstract Background Pathway enrichment analysis (PEA) is a common method for exploring functions of hundreds of genes and identifying disease-risk pathways. Moreover, different pathways exert their functions through crosstalk. However, existing PEA m
Externí odkaz:
https://doaj.org/article/854ec60e76444feaa973fc855e144448
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 13 (2023)
Liver cirrhosis remains a significant global public health concern, with liver transplantation standing as the foremost effective treatment currently available. Therefore, investigating the pathogenesis of liver cirrhosis and developing novel therapi
Externí odkaz:
https://doaj.org/article/00fa6ccd86a6403c934f4ecba103c1cb
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Liver fibrosis is a wound-healing process that occurs in response to severe injuries and is hallmarked by the excessive accumulation of extracellular matrix or scar tissues within the liver. Liver fibrosis can be either acute or chronic and
Externí odkaz:
https://doaj.org/article/5b40fddd5db44f818992052a32e9a899