Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mengnan Guo"'
Autor:
Mengjie Li, Xiaoyan Hao, Zhengwei Hu, Jie Tian, Jingjing Shi, Dongrui Ma, Mengnan Guo, Shuangjie Li, Chunyan Zuo, Yuanyuan Liang, Mibo Tang, Chengyuan Mao, Yuming Xu, Changhe Shi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Alzheimer’s disease (AD) is the most common cause of dementia, characterized by memory loss, cognitive decline, personality changes, and various neurological symptoms. The role of blood–brain barrier (BBB) injury, extracellular matrix (E
Externí odkaz:
https://doaj.org/article/7856c0d91cb142a6a5e0952b06e95cee
Autor:
Changhe Shi, Dongrui Ma, Mengjie Li, Zhiyun Wang, Chenwei Hao, Yuanyuan Liang, Yanmei Feng, Zhengwei Hu, Xiaoyan Hao, Mengnan Guo, Shuangjie Li, Chunyan Zuo, Yuemeng Sun, Mibo Tang, Chengyuan Mao, Chan Zhang, Yuming Xu, Shilei Sun
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract There is considerable uncertainty regarding the associations between various risk factors and Parkinson’s Disease (PD). This study systematically screened and validated a wide range of potential PD risk factors from 502,364 participants in
Externí odkaz:
https://doaj.org/article/a1f6b71a19ab49d387414d6d6ac8fe4c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The application of intelligent technology, such as industrial robots, is related to the environmental governance effectiveness of enterprises and the realization of the goal of “carbon peak and carbon neutrality”. Due to their similar ex
Externí odkaz:
https://doaj.org/article/67f316a184d447efbde7556327a05764
Autor:
Jian Chen, Yanyan Liu, Feixiang Chen, Mengnan Guo, Jiajia Zhou, Pengfei Fu, Xin Zhang, Xueli Wang, He Wang, Wei Hua, Jinquan Chen, Jin Hu, Ying Mao, Dayong Jin, Wenbo Bu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Nanoscale optoelectrodes hold the potential to stimulate optically individual neurons and intracellular organelles, a challenge that demands both a high-density of photoelectron storage and significant charge injection. Here, we report that
Externí odkaz:
https://doaj.org/article/c74b6bab06ae46f0bb4ac286df00a564
Autor:
Xia Wang, Dawei Chen, Mengnan Guo, Yao Ning, Mingze Geng, Jing Guo, Jiahui Gao, Dong Zhao, Yupeng Zhang, Qianpeng Li, Lixiang Li, Shiyang Li, Yanqing Li, Xiaoran Xie, Xiuli Zuo, Jingxin Li
Publikováno v:
Research, Vol 7 (2024)
Colon cancer is increasing worldwide and is commonly regarded as hormone independent, yet recent reports have implicated sex hormones in its development. Nevertheless, the role of hormones from the hypothalamus–hypophysis axis in colitis-associated
Externí odkaz:
https://doaj.org/article/2d97cfebbdec4c2db0ba84db1d9816c7
Autor:
Weixi Chen, Zekun Bai, Wen Bai, Wei Wang, Jiapei Guo, Mengnan Guo, Yingying Sai, Jun Shi, Jinghua Wu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Hepatocellular carcinoma (HCC) is a symptomatic disease involed multi-stage program. Here, we elucidated the molecular mechanism of LncTUG1 in the regulation of HCC evolvement. And that may in all likelyhood supply a innovative latent target
Externí odkaz:
https://doaj.org/article/125dd1ae4be340e98eb2fa2fb709dfe1
Autor:
Jingjing Shi, Jie Tian, Yu Fan, Xiaoyan Hao, Mengjie Li, Jiadi Li, Dongrui Ma, Mengnan Guo, Shuangjie Li, Yuming Xu, Changhe Shi
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: A high level of education or intelligence (IQ) is reported to be a risk factor for Parkinson’s disease (PD). The purpose of this study was to systematically examine the causal relationships between IQ, educational attainment (EA), cogni
Externí odkaz:
https://doaj.org/article/7e69d8f57d954cd5948c2537b2c7e686
Autor:
Mengjie Li, Fen Liu, Xiaoyan Hao, Yu Fan, Jiadi Li, Zhengwei Hu, Jingjing Shi, Liyuan Fan, Shuo Zhang, Dongrui Ma, Mengnan Guo, Yuming Xu, Changhe Shi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Spinocerebellar ataxia 19/22 (SCA19/22) is a rare neurodegenerative disorder caused by mutations of the KCND3 gene, which encodes the Kv4. 3 protein. Currently, only 22 KCND3 single-nucleotide mutation sites of SCA19/22 have been reported worldwide,
Externí odkaz:
https://doaj.org/article/f185e50cbd9f4d29aff921d16b8e2b27
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2022 (2022)
Aims. In this report, it was investigated that hepatoma cells can cause downregulation of cytotoxic T lymphocyte (CTL) function and tea polyphenols (TPs) can reverse downregulation of CTL function. Methods. The expression of GRP78, PD-1, and TIM-3 wa
Externí odkaz:
https://doaj.org/article/b01e46f42f16421aae934fac1c027aa9
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 8, p 243 (2022)
Background: Metabolic activities of tumor cells lead to a depletion of nutrients within the tumor microenvironment, which results in the dysfunction of infiltrating T cells. Here, we explored how glutamine (gln) metabolism, which is essential for bio
Externí odkaz:
https://doaj.org/article/4c3084bc037345f1af22d46d328ef2e1