Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Menglin Xian"'
Autor:
Nana Geng, Mengtian Fan, Biao Kuang, Fengmei Zhang, Menglin Xian, Lin Deng, Cheng Chen, Yiming Pan, Jianqiang Chen, Naibo Feng, Li Liang, Yuanlan Ye, Kaiwen Liu, Xiaoli Li, Yu Du, Fengjin Guo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Osteoarthritis is a degenerative joint disease with joint pain as the main symptom, caused by fibrosis and loss of articular cartilage. Due to the complexity and heterogeneity of osteoarthritis, there is a lack of effective individualized di
Externí odkaz:
https://doaj.org/article/bba95520904141e3b43de147af0e85d8
Autor:
Nana Geng, Menglin Xian, Lin Deng, Biao Kuang, Yiming Pan, Kaiwen Liu, Yuanlan Ye, Mengtian Fan, Zhixun Bai, Fengjin Guo
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 50-62 (2024)
Background: The mechanism by which chondrocyte senescence aggravate OA progression has not yet been well elucidated. The aim of this study was to investigate the chondrocyte senescence related gene biosignatures in OA, and to analyze on the underlyin
Externí odkaz:
https://doaj.org/article/f104f5b25b9e449c80270bf33558c449
Autor:
Li Liang, Fengmei Zhang, Naibo Feng, Biao Kuang, Mengtian Fan, Cheng Chen, Yiming Pan, Pengfei Zhou, Nana Geng, Xingyue Li, Menglin Xian, Lin Deng, Xiaoli Li, Liang Kuang, Fengtao Luo, Qiaoyan Tan, Yangli Xie, Fengjin Guo
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 11, Pp 2376-2389 (2023)
Abstract Osteoarthritis (OA) is a full-joint, multifactorial, degenerative and inflammatory disease that seriously affects the quality of life of patients due to its disabling and pain-causing properties. ER stress has been reported to be closely rel
Externí odkaz:
https://doaj.org/article/eab01dc3044e46f092e390b771dbe2cc
Autor:
Yiming Pan, Yuyou Yang, Mengtian Fan, Cheng Chen, Rong Jiang, Li Liang, Menglin Xian, Biao Kuang, Nana Geng, Naibo Feng, Lin Deng, Wei Zheng, Fengmei Zhang, Xiaoli Li, Fengjin Guo
Publikováno v:
Genes and Diseases, Vol 10, Iss 4, Pp 1582-1595 (2023)
Progranulin (PGRN) is a multifunctional growth factor involved in many physiological processes and disease states. The apparent protective role of PGRN and the importance of chondrocyte autophagic function in the progression of osteoarthritis (OA) le
Externí odkaz:
https://doaj.org/article/10e31adbb73d4ac5bb786b9af75f036a
Autor:
Yiming Pan, Yuyou Yang, Mengtian Fan, Cheng Chen, Rong Jiang, Li Liang, Menglin Xian, Biao Kuang, Nana Geng, Naibo Feng, Lin Deng, Wei Zheng, Fengmei Zhang, Xiaoli Li, Fengjin Guo
Publikováno v:
Genes & Diseases.
Autor:
Yangli Xie, Feng-Jin Guo, Lin Deng, Li Liang, Dongsheng Yu, Mengying Zhang, Yu Du, Yuyou Yang, Xiaoli Li, Mengtian Fan, Cheng Chen, Qizhong Qin, Fangzhou Song, Naibo Feng, Nana Geng, Menglin Xian, Qiaoyan Tan, Fengtao Luo, Rong Jiang, Huabing Qi, Xingyue Li
Publikováno v:
ACS nano. 15(10)
The clinical application of small interfering RNA (siRNA) drugs provides promising opportunities to develop treatment strategies for autoimmune inflammatory diseases. In this study, siRNAs targeting the endoplasmic reticulum to nucleus signaling 1 (E