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Akademický článek

SERS Platform Based on Bimetallic Au-Ag Nanowires-Decorated Filter Paper for Rapid Detection of miR-196ain Lung Cancer Patients Serum

Autor: Ji Xia, Yifan Liu, Menglin Ran, Dan Lu, Xiaowei Cao, Youwei Wang

Publikováno v: Journal of Chemistry, Vol 2020 (2020)

Detecting microRNA (miRNA) biomarkers expression is of great significance for the diagnosis and treatment of lung cancer. Surface-enhanced Raman scattering (SERS) has achieved microRNA sensing for the diagnosis of primary liver cancers. In this work,

Externí odkaz: https://doaj.org/article/0ae731665eea442d9c9bfe6e75eb3445

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Rapid and sensitive detection of dual lung cancer-associated miRNA biomarkers by a novel SERS-LFA strip coupling with catalytic hairpin assembly signal amplification

Autor: Yu Mao, Yue Sun, Yifan Liu, Menglin Ran, Caili Bi, Dan Lu, Xiaowei Cao

Publikováno v: Journal of Materials Chemistry C. 9:3661-3671

A novel surface-enhanced Raman scattering (SERS)-lateral flow assay (LFA) biosensor in combination with catalytic hairpin assembly (CHA) signal amplification has been developed for the analysis of miR-196a-5p and miR-31-5p associated with lung cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::508eae59fbf15100e59db293e060d6cc
https://doi.org/10.1039/d0tc05737a

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Highly sensitive SERS assay of genetically modified organisms in maize via a nanoflower substrate coupled with hybridization chain reaction amplification

Autor: Shengjie Ge, Yifan Liu, Yu Mao, Yue Sun, Xinyu Zhou, Xiaowei Cao, Menglin Ran

Publikováno v: New Journal of Chemistry. 45:20586-20595

Research methods for DNA detection have been widely extended since the application of nanotechnology, but it remains a challenge to detect specific DNA sequences or low abundance genes in biological samples with accuracy and sensitivity. Herein, a no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db236c8dd4c6129cdf3635c55c21710a
https://doi.org/10.1039/d1nj03913j

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A novel DNA biosensor for the ultrasensitive detection of DNA methyltransferase activity based on a high-density 'hot spot' SERS substrate and rolling circle amplification strategy

Autor: Xinyu Zhou, Menglin Ran, Shengjie Ge, Yu Mao, Yue Sun, Li Li, Xiaowei Cao

Publikováno v: The Analyst. 146:5326-5336

Herein, we proposed a novel biosensor based on a high-density "hot spot" Au@SiO2 array substrate and rolling circle amplification (RCA) strategy for the ultrasensitive detection of CpG methyltransferase (M.SssI) activity. In the presence of M.SssI, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce16d0bad8f16514e7dfde4cbdcde70
https://doi.org/10.1039/d1an01034d

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SERS Immunosensor Based on High-Density 'Hotspots' Au@SiO2 Array Substrate and Au-Ag Nanoshells Probes for Ultrasensitive Detection of Dual Biomarkers in the Cervical Cancer Serum

Autor: Menglin Ran, Qilong Song, Yifan Liu, Yue Sun, Xiaowei Cao, Dan Lu

Publikováno v: Nano. 17

Cervical cancer is a common cause of cancer-related death in women worldwide, and quantitative detection of serum tumor markers has practical implications for diagnosing cervical cancer. In this study, a novel surface-enhanced Raman scattering (SERS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1e8f3d082a6b8fa3b1b852ba2fdf596
https://doi.org/10.1142/s1793292022500229

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Prediction of premature rupture of membranes via simultaneous detection of procalcitonin and interleukin-6 by a SERS-based immunochromatographic assay

Autor: Ji Xia, Jiaowei Shang, Liyan Bi, Dan Lu, Menglin Ran, Yifan Liu, Xiaowei Cao

Publikováno v: New Journal of Chemistry. 44:17099-17111

The high incidence of premature rupture of membranes (PROM) is closely related to the lack of screening methods. Herein, a rapid and sensitive detection model for procalcitonin (PCT) and interleukin-6 (IL-6) was established utilizing the principle of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02db1e9933f0898aea5777e51baf42db
https://doi.org/10.1039/d0nj03799k

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A dual-signal amplification strategy based on pump-free SERS microfluidic chip for rapid and ultrasensitive detection of non-small cell lung cancer-related circulating tumour DNA in mice serum

Autor: Xiaowei Cao, Shengjie Ge, Xinyu Zhou, Yu Mao, Yue Sun, Wenbo Lu, Menglin Ran

Publikováno v: Biosensors and Bioelectronics. 205:114110

Circulating tumour DNAs (ctDNAs) have been reported to be associated with real-time information of progression; however, an accurate and sensitive method has not been established. Herein, a novel dual-signal amplification strategy based on a pump-fre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c59a9f1928c4b80f6ae1b93083f9829
https://doi.org/10.1016/j.bios.2022.114110

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The simultaneous detection of the squamous cell carcinoma antigen and cancer antigen 125 in the cervical cancer serum using nano-Ag polydopamine nanospheres in an SERS-based lateral flow immunoassay

Autor: Xiaowei Cao, Menglin Ran, Ji Xia, Liyan Bi, Qian Wang, Dan Lu, Wenbo Lu, Yifan Liu

Publikováno v: RSC advances. 10(49)

The accurate analysis of tumor related biomarkers is extremely critical in the diagnosis of the early stage cervical cancer. Herein, we designed a novel and inexpensive surface-enhanced Raman scattering-based lateral flow assay (SERS-based LFA) strip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0224890ec71784f0a233cfc07e5f495
https://pubmed.ncbi.nlm.nih.gov/35521095

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SERS spectroscopy using Au-Ag nanoshuttles and hydrophobic paper-based Au nanoflower substrate for simultaneous detection of dual cervical cancer-associated serum biomarkers

Autor: Dan Lu, Yifan Liu, Liyan Bi, Menglin Ran, Ji Xia, Xiaowei Cao

Publikováno v: Analytical and bioanalytical chemistry. 412(26)

Ultrasensitive detection of specific biomarkers in clinical serum is helpful for early diagnosis of cervical cancer. In this paper, a surface-enhanced Raman scattering (SERS)-based immunoassay was developed for the simultaneous determination of squam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127fa35fc70a378812799ec65256789f
https://pubmed.ncbi.nlm.nih.gov/32737551

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