Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Menglei Hua"'
Autor:
Meng Wang, Jianmin Wang, Jianxin Ji, Chenjing Ma, Hesong Wang, Jia He, Yongzhen Song, Xuan Zhang, Yong Cao, Yanyan Dai, Menglei Hua, Ruihao Qin, Kang Li, Lei Cao
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3714-3729 (2024)
Identifying novel compound–protein interactions (CPIs) plays a pivotal role in target identification and drug discovery. Although the recent multimodal methods have achieved outstanding advances in CPI prediction, they fail to effectively learn bot
Externí odkaz:
https://doaj.org/article/52469048380a49458fcb735dbf065396
Autor:
Xue Li, Ying Cheng, Zhifu Yang, Qifeng Ji, Menglei Huan, Weiliang Ye, Miao Liu, Bangle Zhang, Daozhou Liu, Siyuan Zhou
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Glioma is easy to develop resistance to temozolomide (TMZ). TMZ-resistant glioma secretes interleukin-10 (IL-10) and transforming growth factor-β (TGF-β), recruiting regulatory T cell (Treg) and inhibiting the activity of T cells and natur
Externí odkaz:
https://doaj.org/article/5f366a44e7a94331ba558352f8ac8e89
Autor:
Daozhou Liu, Qifeng Ji, Ying Cheng, Miao Liu, Bangle Zhang, Qibing Mei, Menglei Huan, Siyuan Zhou
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Ischemic stroke is one of the main causes of death and disability in the world. The treatment for ischemic stroke is to restore blood perfusion as soon as possible. However, when ischemic brain tissue is re-perfused by blood, the
Externí odkaz:
https://doaj.org/article/27462561b87a402ca0bc419e6c9d0b31
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 1, Pp 82-89 (2007)
To find a more potent alternative with less estrogen-related side effects for hormone replacement therapy, we designed and synthesized a nitric oxide (NO)-releasing prodrug of genistein, named NO-donating genistein (NO-G). The characteristics of NO-G
Externí odkaz:
https://doaj.org/article/4acd1a3bd8714199977a21defd197501
Autor:
Menglei Huan, Bangle Zhang, Zenghui Teng, Han Cui, Jieping Wang, Xinyou Liu, Hui Xia, Siyuan Zhou, Qibing Mei
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44116 (2012)
BackgroundConventional chemotherapy agent such as doxorubicin (DOX) is of limited clinical use because of its inherently low selectivity, which can lead to systemic toxicity in normal healthy tissue.MethodsA pH stimuli-sensitive conjugate based on po
Externí odkaz:
https://doaj.org/article/cc8936b69110404391661108caa659af
Autor:
Zenghui Teng, Chengjun Yuan, Feng Zhang, Menglei Huan, Weidong Cao, Kangchu Li, Jingyue Yang, Dayong Cao, Siyuan Zhou, Qibing Mei
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29647 (2012)
BACKGROUND: Polyphenols, a group of complex naturally occurring compounds, are widely distributed throughout the plant kingdom and are therefore readily consumed by humans. The relationship between their chemical structure and intestinal absorption,
Externí odkaz:
https://doaj.org/article/76b5af9600994a6f843de605cd8dcee5