Zobrazeno 1 - 10
of 383
pro vyhledávání: '"Mengke Li"'
Autor:
Jian Zhang, Yiqun Du, Yanchun Meng, Xiaojun Liu, Yuxin Mu, Yunpeng Liu, Yehui Shi, Jufeng Wang, Aimin Zang, Shanzhi Gu, Tianshu Liu, Huan Zhou, Hongqian Guo, Silong Xiang, Xialu Zhang, Suqiong Wu, Huanhuan Qi, Mengke Li, Xichun Hu
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract DP303c is a HER2-targeted ADC with a cleavable linker-MMAE payload. Previous in vitro studies demonstrated that DP303c showed similar or better antitumor activity than T-DM1 in xenograft models. This was a multicenter, dose escalation and do
Externí odkaz:
https://doaj.org/article/e373209687f84f2f8062a4819767885a
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 278-286 (2024)
G protein-coupled receptors (GPCRs) play a pivotal role in fundamental biological processes and disease development. GPCR isoforms, derived from alternative splicing, can exhibit distinct signaling patterns. Some highly-truncated isoforms can impact
Externí odkaz:
https://doaj.org/article/4d30c59b93d849df85e4eeb7b8ddb588
Autor:
Ling Huang, Wei Tang, Lina He, Mengke Li, Xian Lin, Ao Hu, Xindi Huang, Zhouyu Wu, Zhiyong Wu, Shiyun Chen, Yangbo Hu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Influenza virus infection remains a major global health problem and requires a universal vaccine with broad protection against different subtypes as well as a rapid-response vaccine to provide immediate protection in the event of an epidemic
Externí odkaz:
https://doaj.org/article/68693459a30349a7ae4eda1e5182e82c
Autor:
Yanjing Huang, Zhong Liu, Mengke Li, Dongliang Wang, Jinguo Ye, Qiuling Hu, Qikai Zhang, Yuheng Lin, Rongxin Chen, Xuanwei Liang, Xingyi Li, Xianchai Lin
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Background Aging is associated with significant structural and functional changes in the spleen, leading to immunosenescence, yet the detailed effects on splenic vascular endothelial cells (ECs) and their immunomodulatory roles are not fully
Externí odkaz:
https://doaj.org/article/e901b34da808471eafd0aaee0d45398d
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Evidence suggests that radiotherapy is a potent immunomodulator in non-small cell lung cancer (NSCLC). Conversely, it has rarely been demonstrated if immune infiltration can influence radiotherapy efficacy. Herein, we explored the
Externí odkaz:
https://doaj.org/article/65f8599ecb0a4b47b5ba47dde1e15a95
Autor:
Mengke Li, Hongzhi Tang, Rui Qing, Yanze Wang, Jiongqin Liu, Rui Wang, Shan Lyu, Lina Ma, Ping Xu, Shuguang Zhang, Fei Tao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Membrane proteins are critical to biological processes and central to life sciences and modern medicine. However, membrane proteins are notoriously challenging to study, mainly owing to difficulties dictated by their highly hydrophobic natur
Externí odkaz:
https://doaj.org/article/162d950fc728486688aa9461b3cb073e
Autor:
Li Li, Kewen He, Tao Zhou, Yang Xu, Jiaohui Pang, Qingxi Yu, Yongsheng Gao, Hongjin Shi, He Zhu, Mengke Li, Jinming Yu, Shuanghu Yuan
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1649-1664 (2024)
Stage pIIIA/N2 non‐small cell lung cancer (NSCLC) is primarily treated by complete surgical resection combined with neoadjuvant/adjuvant therapies. However, up to 40% of patients experience tumor recurrence. Here, we studied 119 stage pIIIA/N2 NSCL
Externí odkaz:
https://doaj.org/article/e5aa2ebe6820457a9b5c97ae20b2adfd
Autor:
Wen Li, Mingyang Liu, Mengke Li, Ruomin Sun, Tenglong Zhou, Yaqi He, Jianing Mao, Chang Liu, Lei Ma, Shenglei Fu
Publikováno v:
Forestry Research, Vol 4, Iss 1, Pp 1-9 (2024)
Plant functional traits are indicative of plant responses to environmental changes, influencing ecosystem functions. Leaves, as a key focus in studying plant functional traits, present an area where the impact of nitrogen deposition and altered rainf
Externí odkaz:
https://doaj.org/article/507129d813c247048f46f3f72b074615
Autor:
Hengyang Dong, Yujie Wu, Hongbo Zheng, Pandi Chen, Wenhao Deng, Liuhong Ma, Xinyuan Dong, Zhiyong Duan, Mengke Li
Publikováno v:
Photonics, Vol 11, Iss 10, p 906 (2024)
A Si-based photodetector is the core device of Si-based optical interconnection; its material and performance are the key factors restricting its development. This paper conducts theoretical research on the issues of lattice mismatch between heteroge
Externí odkaz:
https://doaj.org/article/f965a4a6f6244d10ac9de237999a5792
Autor:
Zhida Gu, Mengke Li, Cheng Chen, Xinglong Zhang, Chengyang Luo, Yutao Yin, Ruifa Su, Suoying Zhang, Yu Shen, Yu Fu, Weina Zhang, Fengwei Huo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Hydrogen spillover is the migration of activated hydrogen atoms from a metal particle onto the surface of catalyst support, which has made significant progress in heterogeneous catalysis. The phenomenon has been well researched on oxide supp
Externí odkaz:
https://doaj.org/article/6b4ebc6b47e04ed3a905eadd15c9bf4a