Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Mengjie Rui"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundThe identification of compound-protein interactions (CPIs) is crucial for drug discovery and understanding mechanisms of action. Accurate CPI prediction can elucidate drug-target-disease interactions, aiding in the discovery of candidate co
Externí odkaz:
https://doaj.org/article/0c61054e99a84183bdf514077d5624ab
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
While synergistic drug combinations are more effective at fighting tumors with complex pathophysiology, preference compensating mechanisms, and drug resistance, the identification of novel synergistic drug combinations, especially complex higher-orde
Externí odkaz:
https://doaj.org/article/7c4594aba65948bd86991c9c8cf56724
Publikováno v:
Chinese Medicine, Vol 15, Iss 1, Pp 1-16 (2020)
Abstract Background Due to the lack of enough interaction data among compositions, targets and diseases, it is difficult to construct a complete network of Traditional Chinese Medicine (TCM) that comprehensively reflects active compositions and their
Externí odkaz:
https://doaj.org/article/b01eefd5f3c249f8b0c3b60d4858f830
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 546-556 (2020)
Liposomes, as one of the most successful nanotherapeutics, have a major impact on many biomedical areas. In this study, we performed laser scanning confocal microscope (LSCM) and immunohistochemistry (IHC) assays to investigate the intra-tumor transp
Externí odkaz:
https://doaj.org/article/ecb9d348b535411d861d6cbb94871973
Autor:
Mengjie Rui, Min Cai, Yu Zhou, Wen Zhang, Lianglai Gao, Ke Mi, Wei Ji, Dan Wang, Chunlai Feng
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 556 (2022)
Notch signaling is a key parameter in regulating cell fate during tissue homeostasis, and an aberrant Notch pathway can result in mammary gland carcinoma and has been associated with poor breast cancer diagnosis. Although inhibiting Notch signaling w
Externí odkaz:
https://doaj.org/article/420fe00226784e8f96ffb5dd4456ef3d
Publikováno v:
Chinese Medicine, Vol 15, Iss 1, Pp 1-16 (2020)
Chinese Medicine
Chinese Medicine
Background Due to the lack of enough interaction data among compositions, targets and diseases, it is difficult to construct a complete network of Traditional Chinese Medicine (TCM) that comprehensively reflects active compositions and their synergis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09af44716a6d8a630038e0607f7de084
http://link.springer.com/article/10.1186/s13020-020-00369-z
http://link.springer.com/article/10.1186/s13020-020-00369-z
Autor:
Siqi Wang, Jianping Yang, Hengwei Chen, Kexin Chu, Xuefei Yu, Yaqiong Wei, Haixia Zhang, Mengjie Rui, Chunlai Feng
Publikováno v:
AAPS PharmSciTech. 23
Engineering pharmaceutical formulations is governed by a number of variables, and the finding of the optimal preparation is intricately linked to the exploration of a multiparametric space through a variety of optimization tasks. As a result, making
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05bb9711998194fc877b22e58c64aff
https://doi.org/10.1208/s12249-022-02210-2
https://doi.org/10.1208/s12249-022-02210-2
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 546-556 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 546-556 (2020)
Liposomes, as one of the most successful nanotherapeutics, have a major impact on many biomedical areas. In this study, we performed laser scanning confocal microscope (LSCM) and immunohistochemistry (IHC) assays to investigate the intra-tumor transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efdd861e20aabbac8b392f8fac15037
http://europepmc.org/articles/PMC7049609
http://europepmc.org/articles/PMC7049609
Publikováno v:
International Journal of Biological Macromolecules. 125:700-710
Fisetin is a natural flavonoid with promising antitumor activity, whereas its clinical application is limited by its hydrophobic property. In this study, we aimed to load fisetin into poly(lactic acid) (PLA) nanoparticles to increase fisetin's solubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9899973dc7c64e997b68eef8ef398f0
https://doi.org/10.1016/j.ijbiomac.2018.12.003
https://doi.org/10.1016/j.ijbiomac.2018.12.003
Publikováno v:
Journal of chromatography. A. 1624
In this short communication, we report the use of a second-generation macrolide antibiotic, gamithromycin (Gam), as a novel chiral selector for enantioseparation in capillary electrophoresis (CE). A preliminary analysis of the experiment results show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837332a593315b0da8ee90e364d0d1a4
https://pubmed.ncbi.nlm.nih.gov/32327223
https://pubmed.ncbi.nlm.nih.gov/32327223