Neutralization of Nogo-A enhances synaptic plasticity in the rodent motor cortex and improves motor learning in vivo

Autor: Yves Kellner, Karin Lussi, Raul Vicente, Ajmal Zemmar, Andreas R. Luft, Oliver Weinmann, Marta Zagrebelsky, Yi Zuo, Miriam Gullo, Mengia Rioult-Pedotti, Martin E. Schwab, Hansjörg Kasper, Zorica Ristic, Xinzhu Yu

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 34, iss 26
Journal of Neuroscience

The membrane protein Nogo-A is known as an inhibitor of axonal outgrowth and regeneration in the CNS. However, its physiological functions in the normal adult CNS remain incompletely understood. Here, we investigated the role of Nogo-A in cortical sy

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