Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Menghua Xiang"'
Autor:
Chuang Yuan, Kelong Ai, Menghua Xiang, Chengliang Xie, Mingyi Zhao, Ming Wu, Hongli Li, Yueren Wu, Yueqing Cao, Can Li, Yanjun Zhong, Xiaomeng Pei, Helen Ka Wai Law, Liqian Gao, Qicai Xiao, Xinyu Yang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-14 (2022)
Abstract Sepsis is a life-threatening syndrome with disturbed host responses to severe infections, accounting for the majority of death in hospitalized patients. However, effective medicines are currently scant in clinics due to the poor understandin
Externí odkaz:
https://doaj.org/article/f48bfedd5a9046e6a9a2424d7abe9271
Autor:
Liang Lou, Shizhe Zhou, Sijia Tan, Menghua Xiang, Wei Wang, Chuang Yuan, Liqian Gao, Qicai Xiao
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
5-aminolevulinic acid (ALA) is a clinically approved prodrug involved in intracellular Heme biosynthesis to produce the natural photosensitizer (PS) Protoporphyrin IX (PpIX). ALA based photodynamic therapy (PDT) has been used to treat various maligna
Externí odkaz:
https://doaj.org/article/eff54de5c2dc491494e8b2f310b0cbb1
Autor:
Peng Chen, Guanghui Tang, Chengjun Zhu, Jie Sun, Xuan Wang, Menghua Xiang, Huisi Huang, Wei Wang, Lin Li, Zhi-Min Zhang, Liqian Gao, Shao Q. Yao
Publikováno v:
Journal of the American Chemical Society. 145:3844-3849
Autor:
Peng Chen, Jie Sun, Chengjun Zhu, Guanghui Tang, Wei Wang, Manyi Xu, Menghua Xiang, Chong‐Jing Zhang, Zhi‐Min Zhang, Liqian Gao, Shao Q. Yao
Publikováno v:
Angewandte Chemie. 134
Despite recent interests in developing lysine-targeting covalent inhibitors, no general approach is available to create such compounds. We report herein a general approach to develop cell-active covalent inhibitors of protein kinases by targeting the
Autor:
Wingnang Leung, Shao Q. Yao, Bingjie Mai, Chuang Yuan, Liqian Gao, Chuanshan Xu, Shi Zihan, Yichu Nie, Juan Wu, Qicai Xiao, Menghua Xiang, Pan Wang
Publikováno v:
ACS Applied Materials & Interfaces. 13:11588-11596
Increasing threats from both pathogenic infections and antibiotic resistance highlight the pressing demand for nonantibiotic agents and alternative therapies. Herein, we report several new phenothiazinium-based derivatives, which could be readily syn
Autor:
Shao Q. Yao, Liang Lou, Liqian Gao, Qicai Xiao, Menghua Xiang, Xiao Dong, Shizhe Zhou, Fen Yang
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 27(59)
Mitochondrion is a promising target in cancer therapy. However, gaining access to this organelle is difficult due to the obstacles to cross the complicated mitochondrial membrane. Cell-penetrating peptides (CPPs) with mitochondrion-targeting ability,
Autor:
Qicai Xiao, Bingjie Mai, Yichu Nie, Chuang Yuan, Menghua Xiang, Zihan Shi, Juan Wu, Wingnang Leung, Chuanshan Xu, Shao Q. Yao, Pan Wang, Liqian Gao
Publikováno v:
ACS Applied Materials & Interfaces. 14:45076-45076
Autor:
Menghua Xiang, Xuan Wang, Huai-Jin Ma, Wei Wang, Liqian Gao, Yan-Yu Huang, Liu-Xia Feng, Yan Huang, Wen-Jing Shi, Yong-Feng Wei
Publikováno v:
Talanta. 233
A novel near-infrared-emitting aza-BODIPY-based fluorescent probe with two tellurium atoms at two upper benzyl rings has been prepared and explored for its fluorescent sensing properties towards hypochlorous acid/hypochorite (HClO/ClO−), which show
Autor:
Xuan Wang, Fen Yang, Xiaojun Xu, Qicai Xiao, Shi Zihan, Liqian Gao, Bigyan Sharma, Jia Yan, Li Mengchu, Tongkai Chen, Menghua Xiang, Yichu Nie, Li Shaoyun, Wei Wang, Quanming Zhou
Publikováno v:
Current medicinal chemistry. 28(31)
Photodynamic Therapy (PDT), as a clinically approved modality for the treatment of various disordered diseases including cancer, has received great advances in recent years. By preferentially accumulating non-toxic Photosensitizers (PSs) in the patho
Autor:
Liqian Gao, Jun Shen, Wei Wang, Menghua Xiang, Qicai Xiao, Laxman Pokhrel, Bigyan Sharma, Jia Yan, Quanming Zhou, Xie Liuxing, Fen Yang, Wanting Lv, Shizhe Zhou, Wenbin Deng
Publikováno v:
European journal of medicinal chemistry. 199
Protein Tyrosine Phosphatase 1B (PTP1B), as one of the most important members in PTP superfamily, plays a vital role in conducting various cellular functions. So far, PTP1B has been reported to be involved in the development of many diseases includin