Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Menghua Cai"'
Autor:
Jingyi Han, Xue Zhang, Menghua Cai, Feng Tian, Yi Xu, Hui Chen, Wei He, Jianmin Zhang, Hui Tian, Xiangxiang Pan
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 13, Pp 1592-1602 (2024)
Abstract. Background:. Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in many critically ill patients. Although inflammasome activation plays an important role in the induction of acute lung injury (ALI) and ARDS,
Externí odkaz:
https://doaj.org/article/07fbe0ca281d4c239ec5d6d143f1d08b
Autor:
Yue Wang, Jingyi Han, Dongdong Wang, Menghua Cai, Yi Xu, Yu Hu, Hui Chen, Wei He, Jianmin Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract γδ T cells have the unique ability to detect a wide range of tumors with low mutation burdens, making them attractive candidates for CAR-T-cell therapy. Unlike αβ T cells and other immune cells, γδ T cells are superior in MHC non-restr
Externí odkaz:
https://doaj.org/article/a5fceb5e03b34aefa99d6938225ee962
Autor:
Tong Huo, Xueting Yuan, Jingyi Han, Jia Shi, Yuehan Xiong, Feng Tian, Zihan Xu, Menghua Cai, Yi Xu, Hui Chen, Xiaofeng Zeng, Wei He, Qian Wang, Jianmin Zhang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Idiopathic inflammatory myopathy (IIM) is a heterogeneous group of autoimmune diseases with various clinical manifestations, treatment responses, and prognoses. According to the clinical manifestations and presence of different myositis-specific auto
Externí odkaz:
https://doaj.org/article/0d6e293e25ac471a92c479a106e950a1
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Spondyloarthritis (SpA) refers to a group of diseases with inflammation in joints and spines. In this family, ankylosing spondylitis (AS) is a rare but classic form that mainly involves the spine and sacroiliac joint, leading to the loss of flexibili
Externí odkaz:
https://doaj.org/article/8f272014e1f9457a90a1126d9a9b440e
Autor:
Chao Li, Han Zhang, Kexin Tong, Menghua Cai, Fei Gao, Jia Yang, Yi Xu, Huaishan Wang, Hui Chen, Yu Hu, Wei He, Jianmin Zhang
Publikováno v:
Cells, Vol 12, Iss 16, p 2032 (2023)
Thorase belongs to the AAA+ ATPase family, which plays a critical role in maintaining cellular homeostasis. Our previous work reported that Thorase was highly expressed in brain tissue, especially in the cerebellum. However, the roles of Thorase in t
Externí odkaz:
https://doaj.org/article/3b8a4429fc3742b19da82082073902cc
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Background: Long noncoding RNAs (lncRNAs) crucially modulate DNA damage responses/repair in cancer cells. However, the underlying regulatory role of genome integrity and its clinical value in colon adenocarcinoma (COAD) remains unclear. This study li
Externí odkaz:
https://doaj.org/article/a2948c4c5e2c4f56913942c650770fe0
Autor:
Fei Gao, Han Zhang, Jia Yang, Menghua Cai, Qi Yang, Huaishan Wang, Yi Xu, Hui Chen, Yu Hu, Wei He, Jianmin Zhang
Publikováno v:
Cells, Vol 11, Iss 19, p 2990 (2022)
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and is pathologically characterized by α-synucleinopathy, which is harmful to dopaminergic neurons. However, the underlying mechanisms and pathogenesis of PD remain uncl
Externí odkaz:
https://doaj.org/article/183705e1f0c54cb4ad389269c4e82d38
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
Parkinson’s means Parkinson’s disease, a chronic degenerative disease of central nervous system. The main area which is affected by this disease is motor system. Since it firstly founded by James Parkinson in his 1817 publication, nowadays, peopl
Externí odkaz:
https://doaj.org/article/bd4e5cdf54fc4317a302a8cf543367b7
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Alzheimer’s disease (AD) is the most frequent cause of dementia among neurodegenerative diseases. Two factors were hypothesized to be involved in the pathogenesis of AD, namely beta-amyloid cascade and tauopathy. At present, accumulating evidence s
Externí odkaz:
https://doaj.org/article/cddbe96f1437481883c6866cf034fda1
Autor:
Xue Zhang, Jingyi Han, Yi Xu, Menghua Cai, Fei Gao, Jiajia Han, Dongdong Wang, Yi Fu, Hui Chen, Wei He, Jianmin Zhang
Publikováno v:
Cells, Vol 11, Iss 5, p 856 (2022)
Background: the 18-kDa translocator protein (TSPO) is a mitochondrial outer membrane protein, and its expression tends to increase in response to inflammatory stimulation, rapidly. However, the role of TSPO in inflammation and pyroptosis is not yet c
Externí odkaz:
https://doaj.org/article/350c377915114fd6a18267f59e64ae69