Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mengdie Dong"'
Autor:
Mengdie Dong, Yunjia Zhang, Minghong Chen, Yongkang Tan, Jiao Min, Xian He, Fuhao Liu, Jiaming Gu, Hong Jiang, Longbin Zheng, Jiajing Chen, Quanwen Yin, Xuesong Li, Xiang Chen, Yongfeng Shao, Yong Ji, Hongshan Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3027-3048 (2024)
Endothelial-to-mesenchymal transition (EndMT) is a key driver of atherosclerosis. Aerobic glycolysis is increased in the endothelium of atheroprone areas, accompanied by elevated lactate levels. Histone lactylation, mediated by lactate, can regulate
Externí odkaz:
https://doaj.org/article/d3ba451a29bb44e98b710d533a1ad252
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionImproving the quantity and quality of veterinary talent cultivation is an urgent issue to address in current veterinary education and is key to enhancing veterinary talent competitiveness. Starting from an industrial perspective, the intr
Externí odkaz:
https://doaj.org/article/0d0aec57686d4a7b938dd269b11c2a9e
Autor:
Yunjia Zhang, Hong Jiang, Mengdie Dong, Jiao Min, Xian He, Yongkang Tan, Fuhao Liu, Minghong Chen, Xiang Chen, Quanwen Yin, Longbin Zheng, Yongfeng Shao, Xuesong Li, Hongshan Chen
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114180- (2024)
Summary: Macrophage activation is a hallmark of atherosclerosis, accompanied by a switch in core metabolism from oxidative phosphorylation to glycolysis. The crosstalk between metabolic rewiring and histone modifications in macrophages is worthy of f
Externí odkaz:
https://doaj.org/article/2299ea31c6174322a80a3f73287f55f2
Autor:
Xuesong Li, Xiang Chen, Longbin Zheng, Minghong Chen, Yunjia Zhang, Ruigong Zhu, Jiajing Chen, Jiaming Gu, Quanwen Yin, Hong Jiang, Xuan Wu, Xian Ji, Xin Tang, Mengdie Dong, Qingguo Li, Yuanqing Gao, Hongshan Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 4765-4784 (2023)
Inflammation-driven endothelial dysfunction is the major initiating factor in atherosclerosis, while the underlying mechanism remains elusive. Here, we report that the non-canonical stimulator of interferon genes (STING)–PKR-like ER kinase (PERK) p
Externí odkaz:
https://doaj.org/article/996496edd3a74a9bb03112cfcbe66a0f
Autor:
Longbin Zheng, Xiang Chen, Quanwen Yin, Jiaming Gu, Jiajing Chen, Minghong Chen, Yunjia Zhang, Mengdie Dong, Hong Jiang, Ning Yin, Hongshan Chen, Xuesong Li
Publikováno v:
Biochemical and Biophysical Research Communications. 635:120-127
Macrophage polarization plays a crucial role in atherosclerosis (AS), which is closely associated with energy metabolism. However, the underlying mechanism remains elusive. Hepatoma-derived growth factor (HDGF) has been reported to promote tumor meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ec3ef4c5eb93ab6f580635b0ce64cc
https://doi.org/10.1016/j.bbrc.2022.10.032
https://doi.org/10.1016/j.bbrc.2022.10.032
Autor:
Jiaming Gu, Jiajing Chen, Quanwen Yin, Mengdie Dong, Yunjia Zhang, Minghong Chen, Xiang Chen, Jiao Min, Xian He, Yongkang Tan, Longbin Zheng, Hong Jiang, Bingjian Wang, Xuesong Li, Hongshan Chen
Publikováno v:
Arteriosclerosis, Thrombosis & Vascular Biology; Jan2024, Vol. 44 Issue 1, p156-176, 21p
Publikováno v:
Organic Chemistry Frontiers. 9:3039-3044
A chiral NHC catalyst reacts with α,β-γ,δ-diunsaturated aldehydes to generate an extended Breslow intermediate. Upon δ-protonation and tautomerization, the resulting α,β-unsaturated acyl azolium undergoes [3 + 3] annulation with enamines to af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eab80a1ec69ccd2709bf9d4ffbae03a6
https://doi.org/10.1039/d2qo00257d
https://doi.org/10.1039/d2qo00257d
Autor:
Xiao-Yong, Duan, Zhaohui, Tian, Binghao, Liu, Tao, He, Liang-Liang, Zhao, Mengdie, Dong, Pengna, Zhang, Jing, Qi
Publikováno v:
Organic letters. 23(9)
In this work, the NHC-catalyzed Michael/Mannich/lactamization cascade reaction of enals with either indole-2-carboxaldehyde-derived aldimines or indole-7-carboxaldehyde-derived aldimines is described. This protocol enables the rapid assembly of optic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b662ff8fb82fd55f1430d191fd8caeaf
https://pubmed.ncbi.nlm.nih.gov/33891421
https://pubmed.ncbi.nlm.nih.gov/33891421