Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Mengdi He"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis of the affected joints. Total glucosides of paeony (TGP) capsules have been widely used clinically for the treatment of RA with good efficacy and safety
Externí odkaz:
https://doaj.org/article/966ab5215968420d83bdd0e92c8c1a68
Autor:
Chen Zhang, Kankan Cao, Moran Yang, Yiying Wang, Mengdi He, Jiaqi Lu, Yan Huang, Guodong Zhang, Haiou Liu
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTHigh-grade serous ovarian cancer (HGSC), with a modest response to immune checkpoint blockade (ICB) targeting PD-1/PD-L1 monotherapy, is densely infiltrated by M2-polarized tumor-associated macrophages (TAMs) and regulatory T (Treg) cells. Th
Externí odkaz:
https://doaj.org/article/9e003a2ff4884840add9d913c51a6351
Autor:
Yan Huang, Chen Zhang, Wei Jiang, Moran Yang, Guodong Zhang, Yiying Wang, Mengdi He, Haiou Liu, Kankan Cao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Background The potent immunosuppressive properties of sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) on myeloid cells and lymphocytes provide a strong rationale for serving as a therapeutic target. However, the expression profile and cri
Externí odkaz:
https://doaj.org/article/f73fa218751f49879cb14a4a4098754e
Autor:
Guodong Zhang, Qing Xu, Xiangyun Zhang, Moran Yang, Yiying Wang, Mengdi He, Jiaqi Lu, Haiou Liu
Publikováno v:
Cancer Medicine, Vol 10, Iss 12, Pp 3905-3918 (2021)
Abstract Although the association between tumor‐infiltrating CD3+ T and CD8+ T cells and superior survival in high‐grade serous ovarian cancer (HGSOC) has been observed, the different spatial localization of tumor‐infiltrating lymphocytes (TILs
Externí odkaz:
https://doaj.org/article/d903a904067842c2bc1833b9019cc79b
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2380-2395 (2021)
Abstract Objective Deciphering the determinants of the intralesional immune reaction in cervical carcinogenesis may be conducive to improving the understanding of the disease and then improve outcomes. Methods Public gene‐expression data and full c
Externí odkaz:
https://doaj.org/article/cde053c680804f798b196637921f2846
Publikováno v:
BMC Biotechnology, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Alanine decarboxylase (AlaDC), specifically present in tea plants, is crucial for theanine biosynthesis. Serine decarboxylase (SDC), found in many plants, is a protein most closely related to AlaDC. To investigate whether the new
Externí odkaz:
https://doaj.org/article/8213918ef3c147fd9ce5215eaad26168
Autor:
Shirin Aktar, Peixian Bai, Liubin Wang, Hanshuo Xun, Rui Zhang, Liyun Wu, Mengdi He, Hao Cheng, Liyuan Wang, Kang Wei
Publikováno v:
Plants, Vol 11, Iss 19, p 2483 (2022)
Plant acyl-CoA dominated acyltransferases (named BAHD) comprise a large appointed protein superfamily and play varied roles in plant secondary metabolism like synthesis of modified anthocyanins, flavonoids, volatile esters, etc. Tea (Camellia sinensi
Externí odkaz:
https://doaj.org/article/4ab7c015209845cfbf13906c9d9f9dc7
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Most patients with high-grade serous ovarian cancer (HGSC) lack an effective response to immune checkpoint blockade, highlighting the need for more knowledge about what is required for successful treatment. As follicular cytotoxic CXCR5+CD
Externí odkaz:
https://doaj.org/article/aefa11c2384a4124ac337351d7b47efe
Autor:
Kankan Cao, Guodong Zhang, Xiangyun Zhang, Moran Yang, Yiying Wang, Mengdi He, Jiaqi Lu, Haiou Liu
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Tumor infiltrating mast cells (TIMs), with pro- or anti-tumorigenic role in different types of malignancies, have been implicated in resistance to anti-PD1 therapy. Here, we aimed to identify the relevance of TIMs with the prognosis, immune contextur
Externí odkaz:
https://doaj.org/article/b92d2e80fdac4d4e915201cd4151cd40
Publikováno v:
Diversity, Vol 14, Iss 1, p 27 (2022)
The Qinling Mountains are one of the oldest mountain ranges in China and a global biodiversity research and conservation hotspot. However, there is a lack of systematic research and survey of butterfly diversity in this region. Based on the butterfly
Externí odkaz:
https://doaj.org/article/9e6f98bee2d84497b0243c02fe80afaf