Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mengde Cao"'
Publikováno v:
IEEE Access, Vol 8, Pp 14355-14366 (2020)
As a key module for self-driving cars and advanced driver assistant systems (ADAS), frequency modulation continuous wave (FMCW) automotive millimeter-wave (mmwave) radar has a good market prospect. Due to the relative motion of target and radar in th
Externí odkaz:
https://doaj.org/article/b307ddd2113f4f979e7d0fa6d62368f2
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16966 (2011)
This study aims to investigate apoptosis induced by lexatumumab (Lexa) in hepatocellular carcinoma (HCC) cells. We assessed the sensitivity of HCC cell lines and normal human hepatocytes to Lexa and explored the sensitization of HCC cells to Lexa-ind
Externí odkaz:
https://doaj.org/article/cb9f5a4eb9104f4999298ba36ba15569
Autor:
Mengde Cao, Mitchell R. McGill, Anwar Farhood, C. David Williams, Stanislav I. Svetlov, Archie Svetlov, Hartmut Jaeschke, Steven C. Curry, Matthew R. Sharpe
Publikováno v:
Biomarkers. 19:222-230
Context: New biomarkers are needed in acetaminophen (APAP) hepatotoxicity. Plasma argininosuccinate synthetase (ASS) is a promising candidate.Objective: Characterize ASS in APAP hepatotoxicity.Methods: ASS was measured in plasma from rodents and huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cbf230e8245fe36a6f16a852a6eaec
https://doi.org/10.3109/1354750x.2014.897757
https://doi.org/10.3109/1354750x.2014.897757
Publikováno v:
Biomarkers. 18:242-249
Argininosuccinate synthase (ASS) plays an important role in regulating metabolic functions in mammals. We previously reported that hepatic ASS is released into circulation at very high concentrations in response to endotoxin and acute liver injury. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8a9832c156b1722f628eeeae0d9c86
https://doi.org/10.3109/1354750x.2013.773080
https://doi.org/10.3109/1354750x.2013.773080
Autor:
Xiangxuan Zhao, David R. Nelson, Roniel Cabrera, Chen Liu, Changhai Tian, Ton Wang, William Puszyk, Olorunseun O. Ogunwobi, Mengde Cao
Publikováno v:
Laboratory Investigation. 93:8-19
Sorafenib has been used to treat advanced hepatocellular carcinoma (HCC), but the underlying molecular mechanisms remain controversial and why some patients do not respond to this therapy is poorly understood. In this study, we show that sorafenib tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cb0280d3049f5004efa1fc6d6e375a
https://doi.org/10.1038/labinvest.2012.144
https://doi.org/10.1038/labinvest.2012.144
Publikováno v:
Innate immunity. 22(7)
Sorafenib has been used for the treatment of liver cancer. However, its clinical impact on human immunity system remains poorly known. Our previous study has shown that sorafenib modulates immunosuppressive cell populations in murine liver cancer mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0336a48dfcef2f2825e03ed5fb131a65
https://pubmed.ncbi.nlm.nih.gov/27440860
https://pubmed.ncbi.nlm.nih.gov/27440860
Publikováno v:
International Journal of Radiation Biology. 87:71-80
Purpose To determine the radiosensitivity difference of human Cluster of Differentiation (CD)4(+)CD25(+) regulatory T cells (Treg) and effector T cells to low dose gamma ray and elucidate the underlying mechanisms in vitro. Materials and methods Bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c2f1b58abe75175be48bd58feb61af
https://doi.org/10.3109/09553002.2010.518208
https://doi.org/10.3109/09553002.2010.518208
Autor:
Erika A. Eksioglu, Yiling Xu, Chen Liu, David R. Nelson, Mark A. Atkinson, Clive Wasserfall, Miguel Ararat, Mengde Cao, Roniel Cabrera
Publikováno v:
Scandinavian Journal of Immunology. 72:293-301
Our previous studies showed that high levels of soluble CD25 (sCD25) in the serum of patients with hepatocellular carcinoma (HCC) correlated with blunted effector T-cells (Teff) responses, tumour burden and poor survival. Understanding the interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f89d6a3d322ae9e28400c10fc33b73c
https://doi.org/10.1111/j.1365-3083.2010.02427.x
https://doi.org/10.1111/j.1365-3083.2010.02427.x
Autor:
Clive Wasserfall, Miguel Ararat, Roniel Cabrera, Chen Liu, Yiling Xu, Mark A. Atkinson, David R. Nelson, Mengde Cao
Publikováno v:
Digestive Diseases and Sciences. 55:484-495
The mechanisms involved in hepatocellular carcinoma (HCC) establishing an immunologically tolerogenic tumor environment remain poorly characterized.This study evaluates effector T cell responses and soluble IL-2 receptor alpha chains (sCD25) in relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969d65a5025dd3b978db593a3a9a9078
https://doi.org/10.1007/s10620-009-0955-5
https://doi.org/10.1007/s10620-009-0955-5
Autor:
Mengde Cao, Alan W. Hemming, Haizhen Zhu, Hui-Jia Dong, Erika A. Eksioglu, Chen Liu, David R. Nelson, James M. Crawford
Publikováno v:
Gastroenterology. 133:1649-1659
Background & Aims: Hepatitis C virus (HCV) has a tendency to cause chronic viral infection. Viral evasion of host immune systems plays a key role in the pathogenesis of HCV. However, the interaction between HCV and hepatocyte innate antiviral defense
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcb529cc2ef681b8975cd197dd41ba0
https://doi.org/10.1053/j.gastro.2007.09.017
https://doi.org/10.1053/j.gastro.2007.09.017