Zobrazeno 1 - 10
of 758
pro vyhledávání: '"MengQi, Zhang"'
Autor:
Qi Zhao, Mingxia Jiang, Jiaxuan Liu, Mengqi Zhang, Maiyue He, Shihan Zhou, Jiani Wang, Hongnan Mo, Bo Lan, Peng Yuan, Pin Zhang, Fei Ma, Qiao Li, Binghe Xu
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 10, Pp 934-950 (2024)
Objective: CDK4/6 inhibitors (CDK4/6is) in combination with endocrine therapy have secured a central role in the treatment of hormone receptor (HR)-positive advanced breast cancer (ABC) and have transformed the therapeutic landscape. Cross-line CDK4/
Externí odkaz:
https://doaj.org/article/c9c740e3411248cc8774561a0b366f25
Autor:
Jiaxuan Liu, Maiyue He, Mingxia Jiang, Shihan Zhou, Mengqi Zhang, Yiqun Li, Shanshan Chen, Ruigang Cai, Hongnan Mo, Bo Lan, Fei Ma, Binghe Xu, Qiao Li
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Exploration of novel combination mode of pyrotinib and chemotherapy for heavily pretreated HER2-positive metastatic breast cancer (MBC) and how to balance survival benefits and compliance are still urgent problems in clinical prac
Externí odkaz:
https://doaj.org/article/7f027f026be5409096c94cd702688cf3
Autor:
Mingming Xing, Yang Li, Yuqi Zhang, Juemou Zhou, Danting Ma, Mengqi Zhang, Minglei Tang, Ting Ouyang, Fumiao Zhang, Xiaofeng Shi, Jianyuan Sun, Zuxin Chen, Weiping J. Zhang, Shuli Zhang, Xiangyang Xie
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The paraventricular hypothalamus (PVH) is crucial for food intake control, yet the presynaptic mechanisms underlying PVH neurons remain unclear. Here, we show that RUVBL2 in the PVH is significantly reduced during energy deficit, and knockou
Externí odkaz:
https://doaj.org/article/e355cb264c7f44cd8593ee4bc233abfe
Autor:
Chenfei Zhou, Jinling Jiang, Xiaojun Xiang, Hongli Liu, Guowu Wu, Ruichao Zeng, Tong Lu, Mengqi Zhang, Yuteng Shen, Min Hong, Jun Zhang
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-14 (2024)
Abstract Background Blocking cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) shows substantial antitumor efficacy. Here, we report the preclinical data and outcomes of a first-in-human phase 1a trial of JS007, a novel anti-CTLA-4 antibody, in ad
Externí odkaz:
https://doaj.org/article/31cceefc2b274d07b0c1bbd9ea2b4b65
Autor:
Mingxia Jiang, Yue Chai, Jiaxuan Liu, Maiyue He, Yipeng Wang, Xue Yang, Zeyu Xing, Mengqi Zhang, Shihan Zhou, Fei Ma, Jiayu Wang, Peng Yuan, Binghe Xu, Qiao Li
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Inetetamab is the first domestically developed innovative anti-HER2 monoclonal antibody in China, proven effective and safe in HER2-positive advanced breast cancer. However, its efficacy and safety in neoadjuvant treatment of HER2
Externí odkaz:
https://doaj.org/article/32387e293c134642a179a5d28b93fb22
Autor:
Alicia Zhao, Kowan T. V. O’Keefe, Matthew Binsted, Haewon McJeon, Adriana Bryant, Claire Squire, Mengqi Zhang, Steven J. Smith, Ryna Cui, Yang Ou, Gokul Iyer, Shannon Kennedy, Nate Hultman
Publikováno v:
npj Climate Action, Vol 3, Iss 1, Pp 1-11 (2024)
Abstract Under the next cycle of target setting under the Paris Agreement, countries will be updating and submitting new nationally determined contributions (NDCs) over the coming year. To this end, there is a growing need for the United States to as
Externí odkaz:
https://doaj.org/article/19e2c9e2945e48dfbc5b47fa00d1dbec
Autor:
Yixin Ding, Yangyang Lu, Jing Guo, Shuming Chen, Xiaoxi Han, Shibo Wang, Mengqi Zhang, Rui Wang, Jialin Song, Kongjia Wang, Wensheng Qiu, Weiwei Qi
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-18 (2024)
Abstract Most TRIM family members characterized by the E3-ubiquitin ligases, participate in ubiquitination and tumorigenesis. While there is a dearth of a comprehensive investigation for the entire family in gastric cancer (GC). By combining the TCGA
Externí odkaz:
https://doaj.org/article/2527aa088170497187c3fdf75cb3078d
Autor:
Bharti Manwani, Nivetha Brathaban, Abiya Baqai, Yashee Munshi, Hilda W. Ahnstedt, Mengqi Zhang, Kajsa Arkelius, Ted Llera, Edilberto Amorim, Fanny M. Elahi, Neel S. Singhal
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract L1CAM-positive extracellular vesicles (L1EV) are an emerging biomarker that may better reflect ongoing neuronal damage than other blood-based biomarkers. The physiological roles and regulation of L1EVs and their small RNA cargoes following s
Externí odkaz:
https://doaj.org/article/069193c377204294a1038e245528325a
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Using bone regeneration scaffolds to repair craniomaxillofacial bone defects is a promising strategy. However, most bone regeneration scaffolds still exist some issues such as a lack of barrier structure, inability to precisely match bone de
Externí odkaz:
https://doaj.org/article/2abeef01951546a9a95ffdd99a52e6e2
Autor:
Mingxia Jiang, Jiaxuan Liu, Maiyue He, Mengqi Zhang, Shihan Zhou, Shanshan Chen, Ruigang Cai, Hongnan Mo, Bo Lan, Pin Zhang, Binghe Xu, Qiao Li
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Inetetamab is a novel antibody targeting human epidermal growth factor receptor 2 (HER2) developed in China. Due to its optimized antibody-dependent cell-mediated cytotoxicity effect compared with trastuzumab, it has shown good efficacy a
Externí odkaz:
https://doaj.org/article/84df8beb4c8646e5827cc01f438d0280