Zobrazeno 1 - 10
of 33
pro vyhledávání: '"MengHuan L"'
Autor:
Menghuan Li, Yanting Hou, Yao Chen, Chaoyue Sun, Maodi Liang, Xiaolong Chu, Xin Wen, Fangyuan Yuan, Chaoling Peng, Cuizhe Wang, Jianxin Xie, Jun Zhang
Publikováno v:
Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Objective The release of adipose tissue-derived miRNAs is increased under conditions of obesity, but the exact molecular mechanisms involved have not been elucidated. This study investigated whether obesity-induced increases in palmitic acid
Externí odkaz:
https://doaj.org/article/a8a488fdde45401bad1c90700e1a05a1
Autor:
Xijiao Ren, Rui Xue, Yan Luo, Shuang Wang, Xinyue Ge, Xuemei Yao, Liqi Li, Junxia Min, Menghuan Li, Zhong Luo, Fudi Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Radio-immunotherapy exploits the immunostimulatory features of ionizing radiation (IR) to enhance antitumor effects and offers emerging opportunities for treating invasive tumor indications such as melanoma. However, insufficient dose deposi
Externí odkaz:
https://doaj.org/article/da23f2046da746d584bd9a2a03b2c6bc
Autor:
Xijiao Ren, Zhuo Cheng, Jinming He, Xuemei Yao, Yingqi Liu, Kaiyong Cai, Menghuan Li, Yan Hu, Zhong Luo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Immune-checkpoint inhibitors (ICI) are promising modalities for treating triple negative breast cancer (TNBC). However, hyperglycolysis, a hallmark of TNBC cells, may drive tumor-intrinsic PD-L1 glycosylation and boost regulatory T cell func
Externí odkaz:
https://doaj.org/article/20d0b31b87d7486b9d8dddcae98e8055
Autor:
Xue Li, Chenggang Yuan, Bingqi Yang, Huai Pang, Wei Li, Menghuan Li, Yihan Tang, Dingling Ma, Jianxin Xie, Jingzhou Wang, Jun Zhang
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background In previous study, we found that the content of medium-chain fatty acid Caprylic Acid (FFA C8:0) may be an important risk factor of obesity induced prostate cancer (PCa). However, the relationship between FFA C8:0 and PCa has not
Externí odkaz:
https://doaj.org/article/7b82a188cf2d421caf10ebd167acb61c
Autor:
Menghuan Li, Jing Shi, Yanhui Sheng, Yuqing Zhang, Tingting Wu, Jiaming Yang, Kerui Zhang, Wei Sun, Xiangqing Kong
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background Perirenal fat plays a key role in sustaining pathological high blood pressure. We aim to investigate the efficacy of intervention for perirenal fat mediated by focused power ultrasound (FPU) on primary hypertension. Methods A mult
Externí odkaz:
https://doaj.org/article/045c33b4bd0f476599518a8a35e45f99
Publikováno v:
Advanced Science, Vol 10, Iss 29, Pp n/a-n/a (2023)
Abstract Owing to their mechanical resilience and non‐toxicity, titanium implants are widely applied as the major treatment modality for the clinical intervention against bone fractures. However, the intrinsic bioinertness of Ti and its alloys ofte
Externí odkaz:
https://doaj.org/article/12d9762021d94f7584fe0ceac3fb7ecd
Autor:
Maohua Chen, Yuting Sun, Yanhua Hou, Zhong Luo, Menghuan Li, Yujia Wei, Maowen Chen, Lu Tan, Kaiyong Cai, Yan Hu
Publikováno v:
Bioactive Materials, Vol 18, Iss , Pp 56-71 (2022)
To solve the issue of unsatisfactory recruitment of mesenchymal stem cells (MSCs) around implant in osteoporotic fractures, we fabricated a ROS-responsive system on titanium surface through hydroxyapatite coating and biomolecule grafting. The porous
Externí odkaz:
https://doaj.org/article/8861cf034eb34ba2a8edae2ba53f063e
Autor:
Xiaoyuan Mao, Xuan Wang, Mingzhu Jin, Qin Li, Jining Jia, Menghuan Li, Honghao Zhou, Zhaoqian Liu, Weilin Jin, Yanli Zhao, Zhong Luo
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 9, Pp 3513-3528 (2022)
Recent insights collectively suggest the important roles of lysyl oxidase (LysOX) in the pathological processes of several acute and chronic neurological diseases, but the molecular regulatory mechanisms remain elusive. Herein, we explore the regulat
Externí odkaz:
https://doaj.org/article/27b22144269e447db58574a2de1a9cef
Autor:
Xuan Wang, Yingqi Liu, Chencheng Xue, Yan Hu, Yuanyuan Zhao, Kaiyong Cai, Menghuan Li, Zhong Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Manganese has a crucial role in cGAS-STING-mediated DNA sensing and has emerged as a STING agonist. Here the authors report the design and characterization of a nanosystem incorporating manganese ions and the chemotherapeutic drug β-lapachone, induc
Externí odkaz:
https://doaj.org/article/a6ddbcfbf7af42b1953138a775472dcf
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Surgery is currently a mainstream treatment modality for various solid tumor indications. However, aggressive resection of tumor tissues frequently causes postoperative complications, which severely undermine the well-being of patients. More
Externí odkaz:
https://doaj.org/article/787ad9e4dd6b47dea8b558b02d22d083