Výsledky vyhledávání - "Meng-Qi Xiang"

Ebola Virus Aptamers: From Highly Efficient Selection to Application on Magnetism-Controlled Chips

Autor: Dai-Wen Pang, Zhi-Ling Zhang, Meng-Qi Xiang, Man Tang, Shao-Li Hong

Publikováno v: Analytical chemistry. 91(5)

Aptamers for Ebola virus (EBOV) offer a powerful means for prevention and diagnostics. Unfortunately, few aptamers for EBOV have been discovered yet. Herein, assisted by magnetism-controlled selection chips to strictly manipulate selection conditions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9d328a916090914baf2e57212a6d6a
https://pubmed.ncbi.nlm.nih.gov/30740973

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Involvement of endoplasmic reticulum stress and p53 in lncRNA MEG3-induced human hepatoma HepG2 cell apoptosis

Autor: Meng‑Qi Xiang, Bin Liu, Ling‑Fei Wu, Li‑Xuan Liu, Jia‑Lin Feng, Zhen‑Lun Huang, Rui‑Pei Chen, Guo‑Ping Li

Publikováno v: Oncology Reports. 36:1649-1657

Long non-coding RNAs (lncRNAs) play important roles in diverse biological processes. Although downregulation of lncRNA maternally expressed gene 3 (MEG3) has been identified in several types of cancers, little is known concerning its biological role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6654ba878db4798944bf1d5d784832
https://doi.org/10.3892/or.2016.4919

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LncRNA MEG3 contributes to adenosine-induced cytotoxicity in hepatoma HepG2 cells by downregulated ILF3 and autophagy inhibition via regulation PI3K-AKT-mTOR and beclin-1 signaling pathway

Autor: Ling-Fei Wu, Li-Xuan Liu, Hui Tan, Xiao-Tao Zhou, Meng-Qi Xiang, Hao-Lian Zhan, Yi-Tian Guo, Guo-Ping Li, Ze-Jin Pu

Publikováno v: Journal of cellular biochemistry. 120(10)

Adenosine is a promising cytotoxic reagent for tumors, long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3) has been indicated to play critical roles in tumorigenesis, ILF3 has been recognized as a MEG3-binding protein, however, the roles o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b955bd62fcfed2bc76f9b5d250b2376b
https://pubmed.ncbi.nlm.nih.gov/31144362

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The mechanism of adenosine-mediated activation of lncRNA MEG3 and its antitumor effects in human hepatoma cells

Autor: Ling-Fei Wu, Li-Xuan Liu, Yi-Tian Guo, Wei Deng, Rui-Pei Chen, Rui Li, Meng-Qi Xiang, Ge-Fei Wang, Xiao-Tao Zhou, Ze-Jin Pu

Publikováno v: International Journal of Oncology. 48:421-429

Long non-coding RNA MEG3 is suggested to function as a tumor suppressor. However, the activation mechanism of MEG3 is still not well understood and data are not available on its role under adenosine-induced apoptosis. In this study, HepG2 cells were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574383b9f4e514f0aaa57a686002fc24
https://doi.org/10.3892/ijo.2015.3248

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Enhanced Antitumor Effects of Adenoviral-Mediated siRNA against GRP78 Gene on Adenosine-Induced Apoptosis in Human Hepatoma HepG2 Cells

Autor: Yan-Qing Ye, Ze-Jin Pu, Jia-Lin Feng, Ling-Fei Wu, Yi-Tian Guo, Meng-Qi Xiang, Guan-You Huang, Wei Deng, Qing-Hua Zhang

Publikováno v: International Journal of Molecular Sciences, Vol 15, Iss 1, Pp 525-544 (2014)
International Journal of Molecular Sciences; Volume 15; Issue 1; Pages: 525-544
International Journal of Molecular Sciences

Our previous studies show that adenosine-induced apoptosis is involved in endoplasmic reticulum stress in HepG2 cells. In this study, we have investigated whether knockdown of GRP78 by short hairpin RNA (shRNA) increases the cytotoxic effects of aden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae8e6dc968bc0273c9462ecb3531d94
http://www.mdpi.com/1422-0067/15/1/525

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