Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Meng-Lan Luo"'
Autor:
Meng-Lan Luo, Qian Zhao, Xiang-Hong He, Xin Xie, Hong-Ping Zhu, Feng-Ming You, Cheng Peng, Gu Zhan, Wei Huang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114574- (2023)
Allosteric modulation is a direct and effective method for regulating the function of biological macromolecules, which play vital roles in various cellular activities. Unlike orthosteric modulators, allosteric modulators bind to sites distant from th
Externí odkaz:
https://doaj.org/article/2f425f18ba55454e8fce847445fae2cb
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112827- (2022)
Cancer is a leading cause of death worldwide, and cancer development is often associated with disturbances in the autophagy process. Autophagy is a catabolic process involved in many physiological processes, crucial for cell growth and survival. It i
Externí odkaz:
https://doaj.org/article/3ee838551ba0435aafc04ffb4b700365
Publikováno v:
Organic Letters. 24:8493-8497
Autor:
Qing Mao, Rui Qin, Qian Zhao, Shuai-Jiang Liu, Meng-Lan Luo, Wei Huang, Gu Zhan, Hai-Jun Leng
Publikováno v:
Chinese Chemical Letters. 32:2567-2571
An N-heterocyclic carbene (NHC)-catalysed retro-aldol/aldol cascade reaction of spirooxindole-based β-hydroxyaldehyde has been developed. The ring opening-closure process enables the diastereodivergent synthesis of spirocyclopentaneoxindole products
Autor:
Rui Qin, Ting-Ting Yu, Shuai-Jiang Liu, You-Cheng Wang, Meng-Lan Luo, Ben-Hong Chen, Qian Zhao, Wei Huang
Publikováno v:
The Journal of organic chemistry. 87(8)
Although numerous chiral pyrazolones with a six-membered spirocyclic center at the C4 position have been developed, the asymmetric construction of six-membered oxa-spiropyrazolones is still a challenging task in organic synthesis. Herein, we describe
Autor:
Qing, Mao, Qian, Zhao, Mu-Ze, Li, Rui, Qin, Meng-Lan, Luo, Jing, Xue, Ben-Hong, Chen, Hai-Jun, Leng, Cheng, Peng, Gu, Zhan, Bo, Han
Publikováno v:
The Journal of organic chemistry. 86(21)
Though numerous cyanation reactions have been developed for the synthesis of benzonitriles, the construction of valuable fully substituted benzonitriles is still a challenging task. Herein, we reported a tertiary amine-catalyzed [3 + 3]-benzannulatio
Autor:
Qing Mao, Rui Qin, Meng-Lan Luo, Shuai-Jiang Liu, Ben-Hong Chen, Qian Zhao, Bo Han, Jing Xue, Gu Zhan
Publikováno v:
Organicbiomolecular chemistry. 19(2)
Newly designed 3-((2,2,2-trifluoroethyl)amino)indolin-2-ones were used for the facile synthesis of chiral fluoroalkyl-containing 3,2′-spirooxindole γ-lactam products. The secondary amine-catalysed Michael/hemiaminalization cascade reaction of 3-((
Autor:
Qing Mao, Qian Zhao, Mu-Ze Li, Rui Qin, Meng-Lan Luo, Jing Xue, Ben-Hong Chen, Hai-Jun Leng, Cheng Peng, Gu Zhan, Bo Han
Publikováno v:
Journal of Organic Chemistry; 11/5/2021, Vol. 86 Issue 21, p14844-14854, 11p