Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Meng-Huee Lee"'
Publikováno v:
Biology, Vol 9, Iss 10, p 328 (2020)
Stromal fibroblasts surrounding cancer cells are a major and important constituent of the tumor microenvironment not least because they contain cancer-associated fibroblasts, a unique fibroblastic cell type that promotes tumorigenicity through extrac
Externí odkaz:
https://doaj.org/article/c191b4ea0fb448b196fc5adc97f3d16b
Publikováno v:
Molecules, Vol 24, Iss 2, p 255 (2019)
Renal carcinoma cells express Membrane Type 1-Matrix Metalloproteinase (MT1-MMP, MMP-14) to degrade extracellular matrix components and a range of bioactive molecules to allow metastasis and cell proliferation. The activity of MT1-MMP is modulated by
Externí odkaz:
https://doaj.org/article/2d2dce1fb8b94e198ea67b15d2bf4e3b
Publikováno v:
Investigational new drugs. 40(1)
Background. Peritumoral fibroblasts are key components of the tumor microenvironment. Through remodeling of the extracellular matrix (ECM) and secretion of pro-tumorigenic cytokines, peritumoral fibroblasts foster an immunosuppressive milieu conduciv
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136384 (2015)
Tissue inhibitors of metalloproteinases (TIMPs) are the endogenous inhibitors of the matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinases (ADAMs). TIMP molecules are made up of two domains: an N-terminal domain that associates wi
Externí odkaz:
https://doaj.org/article/8fa955c5e3744ad8b240cb3a33f58724
Publikováno v:
Biology
Biology, Vol 9, Iss 328, p 328 (2020)
Volume 9
Issue 10
Biology, Vol 9, Iss 328, p 328 (2020)
Volume 9
Issue 10
Stromal fibroblasts surrounding cancer cells are a major and important constituent of the tumor microenvironment not least because they contain cancer-associated fibroblasts, a unique fibroblastic cell type that promotes tumorigenicity through extrac
Publikováno v:
Molecular and cellular biology. 39(18)
M embrane t ype 1 - m atrix m etallo p roteinase (MT1-MMP) and t umor necrosis factor α (TNF-α)- c onverting e nzyme (TACE) are prominent membrane-anchored metalloproteinases that regulate the turnover of extracellular matrix (ECM) components and b
Autor:
Pasquapina Ciarmela, You-Guo Chen, Zhen-dan Shi, Bingjie Jiang, Fernando M. Reis, Meng-Huee Lee, Fang-Rong Shen, Anastasia Tsigkou, Felice Petraglia, Claudia Tosti
Publikováno v:
Reproductive Sciences. 22:1597-1602
Uterine leiomyoma is the most common benign neoplasm of female reproductive system, found in about 50% of women in reproductive age. The mechanisms of leiomyoma growth include cell proliferation, which is modulated by growth factors, and deposition o
Publikováno v:
Biomedical Reports. 4:73-78
A disintegrin and metalloproteinase with thombospondin motifs (ADAMTS) 13 and 15 are secreted zinc proteinases involved in the turnover of von Willebrand factor and cancer suppression. In the present study, ADAMTS13 and 15 were subjected to inhibitio
Publikováno v:
Oncotarget
ONCOTARGET
ONCOTARGET
// Bingjie Jiang 1 , Yan Zhang 1 , Jian Liu 1 , Anastasia Tsigkou 1 , Magdalini Rapti 2 , Meng Huee Lee 1 1 Department of Biological Sciences, Xian Jiaotong Liverpool University, Suzhou 215123, China 2 Cancer Research UK Cambridge Institute, Universi
Publikováno v:
Molecular & Cellular Biology; Sep2019, Vol. 39 Issue 18, p1-16, 16p