Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Meng-Dan Lan"'
Publikováno v:
Chinese Chemical Letters. 30:1-6
Now increasing chemical modifications are discovered on genomic DNA and RNA. Up to date, more than 150 chemical modifications are identified in nucleic acids. These chemical modifications do not change the sequence of DNA and RNA, but alter their str
Publikováno v:
Cardiovascular Research
RNA contains diverse modifications that exert an important influence in a variety of cellular processes. So far, more than 150 modifications have been identified in various RNA species, mainly in ribosomal RNA (rRNA), transfer RNA (tRNA), and messeng
Publikováno v:
ACS Chemical Biology. 13:3243-3250
The recent discovery of reversible chemical modifications on messenger RNA (mRNA) has opened a new era of post-transcriptional gene regulation in eukaryotes. Among the 15 types of modifications identified in mRNA of eukaryotes, N7-methylguanosine (m7
Autor:
Na Yang, Yu-Qi Feng, Han-Peng Jiang, Ping Liu, Bi-Feng Yuan, Fang Zheng, Meng-Dan Lan, Jie-Mei Chu
Publikováno v:
Journal of Chromatography A. 1462:90-99
More than 140 modified ribonucleosides have been identified in RNA. Determination of endogenous modified ribonucleosides in biological fluids may serve as non-invasive disease diagnostic strategy. However, detection of the modified ribonucleosides in
Publikováno v:
Chemical Science. 7:5495-5502
Similar to the reversible epigenetic modifications on DNA, dynamic RNA modifications were recently considered to constitute another realm for biological regulation in the form of "RNA epigenetics". 5-Methylcytosine (5-mC) has long been known to be pr
Autor:
Meng-Dan Lan, Qian-Yun Deng, Yu-Qi Feng, Bi-Feng Yuan, Huan Zeng, Jun Xiong, Han-Peng Jiang, Fang Zheng, Chunyan Peng
Publikováno v:
Clinical Epigenetics
Background Aging is a complex phenomenon and characterized by a progressive decline in physiology and function of adult tissues. However, it hasn’t been well established of the correlation between aging and global DNA methylation and hydroxymethyla
Autor:
Jun Xiong, Han-Peng Jiang, Chun-Yan Peng, Qian-Yun Deng, Meng-Dan Lan, Huan Zeng, Fang Zheng, Yu-Qi Feng, Bi-Feng Yuan
Publikováno v:
Clinical Epigenetics; Jul2015, Vol. 7 Issue 1, p1-11, 11p