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Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Patients with BRAF 600E mutated mCRC are associated with specific clinicopathological features and poor prognosis. The relative efficacy of first-line FOLFOXIRI triplet chemotherapy or doublet chemotherapy combined with bevacizuma
Externí odkaz:
https://doaj.org/article/eb74d2392ccd43848b4a98e5e94b2487
Autor:
Atif Ahmed Siddiqui, Emmanuelle Merquiol, Reut Bruck-Haimson, Joud Hirbawi, Hana Boocholez, Irit Cohen, Yonghong Yan, Meng Qiu Dong, Galia Blum, Ehud Cohen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract While the activities of certain proteases promote proteostasis and prevent neurodegeneration-associated phenotypes, the protease cathepsin B (CTSB) enhances proteotoxicity in Alzheimer’s disease (AD) model mice, and its levels are elevated
Externí odkaz:
https://doaj.org/article/e3c24ee5acc343fd87a60513d5ca45ab
In this work, we investigate the quasi-two-body decays $B_c\to D^*h\to D\pi h$ with $h = (K^0,\pi^0,\eta,\eta^{\prime})$ using the perturbative QCD(PQCD) approach. The description of final state interactions between the $D\pi$ pair is achieved throug
Externí odkaz:
http://arxiv.org/abs/2304.13286
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Immune checkpoint inhibitors (ICIs) have achieved remarkable success in clinical research and practice. Notably, liver metastasis is not sensitive to ICIs. Liver locoregional therapies can cause irreversible damage to tumor cells and release
Externí odkaz:
https://doaj.org/article/3669871c9af14f4b9bb4d3021b7eb4bd
Autor:
Xiangyang Chen, Ke Wang, Farees Ud Din Mufti, Demin Xu, Chengming Zhu, Xinya Huang, Chenming Zeng, Qile Jin, Xiaona Huang, Yong-hong Yan, Meng-qiu Dong, Xuezhu Feng, Yunyu Shi, Scott Kennedy, Shouhong Guang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Germ granules are biomolecular condensates present in most animal germ cells. One function of germ granules is to help maintain germ cell totipotency by organizing mRNA regulatory machinery, including small RNA-based gene regulatory pathways
Externí odkaz:
https://doaj.org/article/e60a6a28da724963b1079731422ad276
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: Fruquintinib is a third-line and subsequent targeted therapy for patients with metastatic colorectal cancer (mCRC). Identifying survival predictors after fruquintinib is crucial for optimizing the clinical use of this medication. Objectiv
Externí odkaz:
https://doaj.org/article/529a581f9f254d13bb115aa02a344c22
Autor:
Shen, Xuan-Ming, Zhang, Yuan, Zhang, Shunping, Zhang, Yao, Meng, Qiu-Shi, Zheng, Guangchao, Lv, Siyuan, Wang, Luxia, Boto, Roberto A., Shan, Chongxin, Aizpurua, Javier
In this article, we address the optomechanical effects in surface-enhanced resonant Raman scattering (SERRS) from a single molecule in a nano-particle on mirror (NPoM) nanocavity by developing a quantum master equation theory, which combines macrosco
Externí odkaz:
http://arxiv.org/abs/2210.02639
Autor:
Tao Han, Meng Qiu, Xinxin Niu, Shumei wang, Feng Wang, Jingke Cao, Shanghong Tang, Liping Cheng, Yabo Mei, Huayu Liang, Zhichun Feng, Geyu Chen, Qiuping Li
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Invasive fungal infection (IFI) has become an increasing problem in NICU neonates, and end-organ damage (EOD) from IFI is one of the leading causes of morbidity and mortality in neonates. This study was conducted to summarize clin
Externí odkaz:
https://doaj.org/article/6c1e420f807f47aa8daa80a5c1924cd8
Publikováno v:
Zhonghua yi shi za zhi (Beijing, China : 1980). 51(5)
《医说》和《历代名医蒙求》是产生于宋代的两本医书。两书多次引用了《名医录》，此《名医录》的作者及成书年代，一直未见确切考证。经核对，《医说》引《名医录》共25条，《历代
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e91e6d9ecc434096fa7b2a4188b9bbc
https://pubmed.ncbi.nlm.nih.gov/34794270
https://pubmed.ncbi.nlm.nih.gov/34794270