Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Meng Kang Wong"'
Autor:
Jonathan Lian K Ong, Nur Fatimah Farzanah Jalaludin, Meng Kang Wong, Sheng Hui Tan, Clara Angelina, Sarvesh A. Sukhatme, Trifanny Yeo, Chwee Teck Lim, York Tien Lee, Shui Yen Soh, Tony K.H. Lim, Timothy Kwang Yong Tay, Kenneth Tou En Chang, Zhi Xiong Chen, Amos HP Loh
Publikováno v:
Translational Oncology, Vol 46, Iss , Pp 102008- (2024)
Osteosarcoma is the commonest malignant bone tumor of children and adolescents and is characterized by a high risk of recurrence despite multimodal therapy, especially in metastatic disease. This suggests the presence of clinically undetected cancer
Externí odkaz:
https://doaj.org/article/54b2622737fc48fb9fbca253f177061f
Autor:
Amos H. P. Loh, Clara Angelina, Meng Kang Wong, Sheng Hui Tan, Sarvesh A. Sukhatme, Trifanny Yeo, Su Bin Lim, York Tien Lee, Shui Yen Soh, Wing Leung, Kenneth T. E. Chang, Yong Wei Chua, Syed M. F. Alkaff, Tony K. H. Lim, Chwee Teck Lim, Zhi Xiong Chen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Existing marker-based methods of minimal residual disease (MRD) determination in neuroblastoma do not effectively enrich for the circulating disease cell population. Given the relative size differential of neuroblastoma tumor cells over normal hemato
Externí odkaz:
https://doaj.org/article/59fd66efa5fa4cafad88aaaf99036c3c
Autor:
Rachel L. Y. Wong, Megan R. E. Wong, Chik Hong Kuick, Seyed Ehsan Saffari, Meng Kang Wong, Sheng Hui Tan, Khurshid Merchant, Kenneth T. E. Chang, Matan Thangavelu, Giridharan Periyasamy, Zhi Xiong Chen, Prasad Iyer, Enrica E. K. Tan, Shui Yen Soh, N. Gopalakrishna Iyer, Qiao Fan, Amos H. P. Loh
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Neuroblastoma is the commonest extracranial pediatric malignancy. With few recurrent single nucleotide variations (SNVs), mutation-based precision oncology approaches have limited utility, but its frequent and heterogenous copy number variations (CNV
Externí odkaz:
https://doaj.org/article/c94105f2a340474b8a92a8bcd7d1fcc0
Autor:
Ming Tan, Mohammad Asad, Valerie Heong, Meng Kang Wong, Tuan Zea Tan, Jieru Ye, Kuee Theng Kuay, Jean Paul Thiery, Clare Scott, Ruby Yun‐Ju Huang
Publikováno v:
Molecular Oncology, Vol 13, Iss 4, Pp 757-780 (2019)
Frizzled family receptor 7 (FZD7), a Wnt signaling receptor, is associated with the maintenance of stem cell properties and cancer progression. FZD7 has emerged as a potential therapeutic target because it is capable of transducing both canonical and
Externí odkaz:
https://doaj.org/article/627ec59c33f042d7ac79b4f714ad778a
Autor:
Mei Yoke Chan, Yvonne F. L. Yong, Derrick W. Q. Lian, Zhi Xiong Chen, Enrica E. K. Tan, Michaela S. F. Seng, Sharon Ling, Min Hwee Yong, Prasad Iyer, Yong Chen, Eileen H. Q. Ng, Yong Wei Chua, Esther Hee, Meng Kang Wong, Joyce Ching Mei Lam, Muhammad Fahmy Syed, Mee Hiong Ren, Amos Hong Pheng Loh, Sharon Y.Y. Low, Tony Kiat Hon Lim, Chik Hong Kuick, Kenneth Tou En Chang, Sudhanshi Jain, Sheng Hui Tan, Zhang'e Choo, Shui Yen Soh, Ah Moy Tan, Nurfarhanah Bte Syed Sulaiman
Publikováno v:
Cancer Science
Ex vivo evaluation of personalized models can facilitate individualized treatment selection for patients, and advance the discovery of novel therapeutic options. However, for embryonal malignancies, representative primary cultures have been difficult
Autor:
Khawn D. Tawng, Meng Kang Wong, Bin Tean Teh, Ah Moy Tan, Amos Hong Pheng Loh, Visveswari Ganesan, Shui Yen Soh, Francis Y. L. Chin, Mei Yoke Chan, Elizabeth Wagner, Benjamin N. Loke, Derrick W. Q. Lian, Sudhanshi Jain, York Tien Lee, Kenneth Tou En Chang, Chick Hong Kuick, Siam Wee Sim, Yuhan Zou
Publikováno v:
International Journal of Cancer. 144:1234-1242
Wilms tumor demonstrates significant interethnic epidemiological, histological and outcome differences, and is rare and poorly studied among Asians. We compared the clinicopathological, and loss of heterozygosity (LOH) profile and survival outcomes o
Autor:
Loh, Amos H. P., Angelina, Clara, Meng Kang Wong, Sheng Hui Tan, Sukhatme, Sarvesh A., Yeo, Trifanny, Su Bin Lim, York Tien Lee, Shui Yen Soh, Wing Leung, Chang, Kenneth T. E., Yong Wei Chua, Alkaff, Syed M. F., Lim, Tony K. H., Chwee Teck Lim, Zhi Xiong Chen
Publikováno v:
Frontiers in Oncology; 9/13/2022, Vol. 12, p1-14, 14p
Autor:
Zhongde Zhang, Amos Hong Pheng Loh, Sze Jet Aw, Kenneth Tou En Chang, Minzhi Yin, Vikneswari Rajasegaran, Eva Loh, Jain Sudhanshi, Derrick W. Q. Lian, Jing Ma, Bin Tean Teh, Tse Hui Lim, Shaun Giap Hean Goh, Chik Hong Kuick, Cedric Chuan Young Ng, Jing Quan Lim, Meng Kang Wong, Alwin Hwai Liang Loh, Prasad G. Iyer, Alvin Soon Tiong Lim, Puay Hoon Tan, Angela Goytain, Shi Wang, Tony Ng
Publikováno v:
Histopathology. 72:320-329
Clear cell sarcoma of the kidney (CCSK) is a rare paediatric renal malignant tumour. The majority of CCSKs have internal tandem duplications (ITDs) of the BCOR gene, whereas a minority have the YWHAE-NUTM2 gene fusion. A third 'double-negative' (DN)
Autor:
Victor Kwan Min Lee, Benjamin Nathanael Loke, Kenneth Tou En Chang, Mark Puhaindran, Meng Kang Wong, Jain Sudhanshi, Chik Hong Kuick
Publikováno v:
Journal of Clinical Pathology. 70:697-701
Aims We describe the clinical and pathological features and novel genetic findings of a case of CIC-DUX4 sarcoma occurring in the thigh of a 35-year-old man. Methods Fusion gene detection using a next-generation sequencing-based anchored multiplex PC
Autor:
Ruby Yun-Ju Huang, Ming Tan, Jieru Ye, Valerie Heong, Tuan Zea Tan, Meng Kang Wong, Clare L. Scott, K.T. Kuay, Jean Paul Thiery, Mohammad Asad
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 13, Iss 4, Pp 757-780 (2019)
Molecular Oncology, Vol 13, Iss 4, Pp 757-780 (2019)
Frizzled family receptor 7 (FZD7), a Wnt signaling receptor, is associated with the maintenance of stem cell properties and cancer progression. FZD7 has emerged as a potential therapeutic target because it is capable of transducing both canonical and