Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Meng Amy Li"'
Autor:
Meng Amy Li, Paulo P Amaral, Priscilla Cheung, Jan H Bergmann, Masaki Kinoshita, Tüzer Kalkan, Meryem Ralser, Sam Robson, Ferdinand von Meyenn, Maike Paramor, Fengtang Yang, Caifu Chen, Jennifer Nichols, David L Spector, Tony Kouzarides, Lin He, Austin Smith
Publikováno v:
eLife, Vol 6 (2017)
Execution of pluripotency requires progression from the naïve status represented by mouse embryonic stem cells (ESCs) to a state capacitated for lineage specification. This transition is coordinated at multiple levels. Non-coding RNAs may contribute
Externí odkaz:
https://doaj.org/article/10bac2ec83364a588083e62380429289
Autor:
Austin Smith, Masaki Kinoshita, Sabine Dietmann, Meng Amy Li, William Mansfield, Michael Barber
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Mammalian DNA is widely modified by methylation of cytosine residues. This modification is added to DNA during early development. If methylation is prevented, the embryo dies by midgestation with multiple abnormalities. In this study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c0eb256aba05fbc96d2e9ba37c811c
https://doi.org/10.1073/pnas.2109475118
https://doi.org/10.1073/pnas.2109475118
Autor:
Austin Smith, Masaki Kinoshita, Sabine Dietmann, Meng Amy Li, Michael Barber, William Mansfield
Genome remethylation is essential for mammalian development but specific reasons are unclear. Here we examined embryonic stem (ES) cell fate in the absence of de novo DNA methyltransferases. We observed that ES cells deficient for both Dnmt3a and Dnm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3df881e94b1f064d6996941a02ace3d9
https://doi.org/10.1101/2020.12.20.423404
https://doi.org/10.1101/2020.12.20.423404
Autor:
Anish Dattani, Stanley E. Strawbridge, Daniel Spindlow, Ayaka Yanagida, Meng Amy Li, Jennifer Nichols, Buse Nurten Özel, Sam Myers, Ge Guo, Austin Smith, Giuliano Giuseppe Stirparo, Jian Yang, James Clarke
SUMMARYClassical mouse embryology has established a paradigm of early development driven by sequential lineage bifurcations. Accordingly, mouse embryonic stem cells derived from early epiblast have lost the potency to produce extraembryonic trophecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc8f857a914f86324d8e62366c2c8a19
https://doi.org/10.1101/2020.02.04.933812
https://doi.org/10.1101/2020.02.04.933812
Autor:
Sandra Bernaldo de Quirós, Qi Liang, Hannes Ponstingl, María Soledad Fernández-García, Alexander Strong, George S. Vassiliou, Jorge de la Rosa, Julia Weber, Carlos López-Otín, Rocio Fuente, Emmanouil Metzakopian, Mathias J Friedrich, Juan Cadiñanos, Gary J. Hoffman, Lena Rad, María Teresa Fernández-García, Imran Noorani, Meng Amy Li, Aurora Astudillo, Yang Li, Roland Rad, Allan Bradley
Publikováno v:
Nature genetics
The overwhelming number of genetic alterations identified through cancer genome sequencing requires complementary approaches to interpret their significance and interactions. Here we developed a novel whole-body insertional mutagenesis screen in mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9732a3189b17ff32d95a3185e1e437c7
http://europepmc.org/articles/PMC5409503
http://europepmc.org/articles/PMC5409503
Publikováno v:
The EMBO Journal
During differentiation and reprogramming new cell identities are generated by reconfiguration of gene regulatory networks. Here we combined automated formal reasoning with experimentation to expose the logic of network activation during induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01f68dd654e8bb5b2699481f9ebe214
Autor:
Masaki Kinoshita, Meng Amy Li, Barber, Michael, Mansfield, William, Dietmann, Sabine, Smith, Austin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/21/2021, Vol. 118 Issue 38, p1-11, 11p
Autor:
Jian Yang, James Clarke, Ge Guo, Daniel Spindlow, Anish Dattani, Buse Nurten Özel, Ayaka Yanagida, Giuliano Giuseppe Stirparo, Stanley E. Strawbridge, Sam Myers, Austin Smith, Meng Amy Li, Jennifer Nichols
Publikováno v:
Cell Stem Cell
Summary Classic embryological experiments have established that the early mouse embryo develops via sequential lineage bifurcations. The first segregated lineage is the trophectoderm, essential for blastocyst formation. Mouse naive epiblast and deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ab27e0d0e8e10c9304c29af30cf581
http://europepmc.org/articles/PMC8189439
http://europepmc.org/articles/PMC8189439
Autor:
Maike Paramor, Samuel Robson, Paulo P. Amaral, Meryem Ralser, Jennifer Nichols, Tüzer Kalkan, Fengtang Yang, Lin He, Priscilla Cheung, Ferdinand von Meyenn, Tony Kouzarides, Meng Amy Li, David L. Spector, Caifu Chen, Austin Smith, Masaki Kinoshita, Jan H. Bergmann
Publikováno v:
eLife, Vol 6 (2017)
Execution of pluripotency requires progression from the naïve status represented by mouse embryonic stem cells (ESCs) to a state capacitated for lineage specification. This transition is coordinated at multiple levels. Non-coding RNAs may contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346f38955926ea4b020c13ef1e51feac
https://elifesciences.org/articles/23468
https://elifesciences.org/articles/23468
Autor:
Meng Amy Li, David L. Spector, Austin Smith, Priscilla Cheung, Masaki Kinoshita, Paulo P. Amaral, Jennifer Nichols, Meryem Ralser, Jan H. Bergmann, Ferdinand von Meyenn, Caifu Chen, Maike Paramor, Tüzer Kalkan, Fengtang Yang, Tony Kouzarides, Samuel Robson, Lin He
SummaryExecution of pluripotency requires progression from the naïve status represented by mouse embryonic stem cells (ESCs) to a condition poised for lineage specification. This process is controlled at transcriptional, post-transcriptional and epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b128bbaedc4f926ad949c2fa707750ff