Ampelopsin induces MDA-MB-231 cell cycle arrest through cyclin B1-mediated PI3K/AKT/mTOR pathway in vitro and in vivo

Autor: Meng Minjun, Yang Qiaolu, Ouyang Zhong, Yang Qingmo, Wu Xinyi, Huang Yufan, Su Yonghui, Chen Shuanglong, Chen Wenlin

Publikováno v: Acta Pharmaceutica, Vol 73, Iss 1, Pp 75-90 (2023)

Breast cancer is one of the most common malignant tumors in women and it is the most frequently diagnosed cancer in the world. Ampelopsin (AMP) is a purified component from the root of Ampelopsis grossedentata. It is reported that AMP could significa

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β-glucan from Lentinus edodes inhibits breast cancer progression via the Nur77/HIF-1α axis.

Autor: Zhang X; Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, People's Republic of China., Li T; Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, People's Republic of China., Liu S; Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, People's Republic of China., Xu Y; Vascular Department Zhongshan Hospital of Xiamen University, Xiamen, Fujian 363000, People's Republic of China., Meng M; Vascular Department Zhongshan Hospital of Xiamen University, Xiamen, Fujian 363000, People's Republic of China., Li X; Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, People's Republic of China., Lin Z; Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, People's Republic of China., Wu Q; Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, People's Republic of China., Xue Y; Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, People's Republic of China., Pan Y; Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, People's Republic of China., Alitongbieke G; Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, People's Republic of China.

Publikováno v: Bioscience reports [Biosci Rep] 2020 Dec 23; Vol. 40 (12).