Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.

Autor: Roth Flach RJ; From the Program in Molecular Medicine., Danai LV; From the Program in Molecular Medicine., DiStefano MT; From the Program in Molecular Medicine., Kelly M; Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605., Menendez LG; From the Program in Molecular Medicine., Jurczyk A; From the Program in Molecular Medicine., Sharma RB; Department of Medicine, Division of Endocrinology, Metabolism and Diabetes, and., Jung DY; From the Program in Molecular Medicine., Kim JH; From the Program in Molecular Medicine., Kim JK; From the Program in Molecular Medicine, Department of Medicine, Division of Endocrinology, Metabolism and Diabetes, and., Bortell R; From the Program in Molecular Medicine., Alonso LC; Department of Medicine, Division of Endocrinology, Metabolism and Diabetes, and., Czech MP; From the Program in Molecular Medicine, Michael.Czech@umassmed.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2016 Jul 29; Vol. 291 (31), pp. 16221-30. Date of Electronic Publication: 2016 May 20.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis.

Autor: Roth Flach RJ; Program in Molecular Medicine, Worcester, Massachusetts 01605, USA., Skoura A; Cardiovascular and Metabolic Research Unit, Cambridge, Massachusetts 02139, USA., Matevossian A; Program in Molecular Medicine, Worcester, Massachusetts 01605, USA., Danai LV; Program in Molecular Medicine, Worcester, Massachusetts 01605, USA., Zheng W; Cardiovascular and Metabolic Research Unit, Cambridge, Massachusetts 02139, USA., Cortes C; Cardiovascular and Metabolic Research Unit, Cambridge, Massachusetts 02139, USA., Bhattacharya SK; Worldwide Medicinal Chemistry Pfizer, Cambridge, Massachusetts 02139, USA., Aouadi M; Program in Molecular Medicine, Worcester, Massachusetts 01605, USA., Hagan N; Program in Molecular Medicine, Worcester, Massachusetts 01605, USA., Yawe JC; Program in Molecular Medicine, Worcester, Massachusetts 01605, USA., Vangala P; Program in Molecular Medicine, Worcester, Massachusetts 01605, USA., Menendez LG; Program in Molecular Medicine, Worcester, Massachusetts 01605, USA., Cooper MP; Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA., Fitzgibbons TP; Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA., Buckbinder L; Cardiovascular and Metabolic Research Unit, Cambridge, Massachusetts 02139, USA., Czech MP; Program in Molecular Medicine, Worcester, Massachusetts 01605, USA.

Publikováno v: Nature communications [Nat Commun] 2015 Dec 21; Vol. 6, pp. 8995. Date of Electronic Publication: 2015 Dec 21.

Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides.

Autor: Dai DF; Departments of Pathology, Genome Sciences, Anesthesiology, Environmental Health and Biostatistics, University of Washington, Seattle, WA; and Department of Pharmacology, Weill Cornell Medical College, New York, NY., Hsieh EJ, Chen T, Menendez LG, Basisty NB, Tsai L, Beyer RP, Crispin DA, Shulman NJ, Szeto HH, Tian R, MacCoss MJ, Rabinovitch PS

Publikováno v: Circulation. Heart failure [Circ Heart Fail] 2013 Sep 01; Vol. 6 (5), pp. 1067-76. Date of Electronic Publication: 2013 Aug 09.