Novel non-peptide uracil-derived human gonadotropin-releasing hormone receptor antagonists.

Autor: Ciceri S; Department of Pharmaceutical Sciences, University of Milan, Milan, Italy; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy. Electronic address: samuele.ciceri@unimi.it., Fassi EMA; Department of Pharmaceutical Sciences, University of Milan, Milan, Italy., Vezzoli V; Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy., Bonomi M; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy; Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy., Colombo D; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Ferraboschi P; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Grazioso G; Department of Pharmaceutical Sciences, University of Milan, Milan, Italy., Grisenti P; Chemical-Pharmaceutical Consulting and IP Management, Milan, Italy., Villa S; Department of Pharmaceutical Sciences, University of Milan, Milan, Italy., Castellano C; Department of Chemistry, University of Milan, Milan, Italy., Meneghetti F; Department of Pharmaceutical Sciences, University of Milan, Milan, Italy.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 Dec 05; Vol. 279, pp. 116903. Date of Electronic Publication: 2024 Sep 24.

A hit expansion of 3-benzamidopyrazine-2-carboxamide: Toward inhibitors of prolyl-tRNA synthetase with antimycobacterial activity.

Autor: Pallabothula VSK; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic., Abdalrahman NT; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic., Mori M; Department of Pharmaceutical Sciences, University of Milan, Milan, Italy., Fekri AH; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic., Janďourek O; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic., Konečná K; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic., Paterová P; Department of Clinical Microbiology, University Hospital Hradec Králové, Hradec Králové, Czech Republic., Novák M; Biomedical Research Centre, University Hospital Hradec Králové, Hradec Králové, Czech Republic., Dudášová-Hatoková P; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic., Štěrbová-Kovaříková P; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic., Castellano C; Department of Chemistry, University of Milan, Milan, Italy., Meneghetti F; Department of Pharmaceutical Sciences, University of Milan, Milan, Italy., Villa S; Department of Pharmaceutical Sciences, University of Milan, Milan, Italy., Kuneš J; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic., Juhás M; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.; Faculty of Science, University of Hradec Králové, Hradec Králové, Czech Republic., Zitko J; Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.

Publikováno v: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Aug; Vol. 357 (8), pp. e2400171. Date of Electronic Publication: 2024 May 06.

Structural basis for specific inhibition of salicylate synthase from Mycobacterium abscessus.

Autor: Mori M; Department of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133, Milano, Italy., Cocorullo M; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, Via A. Ferrata 9, 27100, Pavia, Italy., Tresoldi A; Department of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133, Milano, Italy., Cazzaniga G; Department of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133, Milano, Italy., Gelain A; Department of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133, Milano, Italy., Stelitano G; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, Via A. Ferrata 9, 27100, Pavia, Italy., Chiarelli LR; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, Via A. Ferrata 9, 27100, Pavia, Italy., Tomaiuolo M; Institute of Crystallography, National Research Council, Trieste Outstation, Area Science Park - Basovizza, S.S.14 - Km. 163.5, 34149, Trieste, Italy., Delre P; Institute of Crystallography, National Research Council, Via G. Amendola 122/o, 70126, Bari, Italy., Mangiatordi GF; Institute of Crystallography, National Research Council, Via G. Amendola 122/o, 70126, Bari, Italy., Garofalo M; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via F. Marzolo 5, 35131, Padova, Italy., Cassetta A; Institute of Crystallography, National Research Council, Trieste Outstation, Area Science Park - Basovizza, S.S.14 - Km. 163.5, 34149, Trieste, Italy., Covaceuszach S; Institute of Crystallography, National Research Council, Trieste Outstation, Area Science Park - Basovizza, S.S.14 - Km. 163.5, 34149, Trieste, Italy. Electronic address: sonia.covaceuszach@ic.cnr.it., Villa S; Department of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133, Milano, Italy. Electronic address: stefania.villa@unimi.it., Meneghetti F; Department of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133, Milano, Italy.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 Feb 05; Vol. 265, pp. 116073. Date of Electronic Publication: 2023 Dec 20.

Polymersomes as selective drug delivery carriers for innovative anti-TB agents

Autor: Cazzaniga, G., Mori, M., Meneghetti, F., Chiarelli, L.R., Stelitano, G., Batalha, I.L., Battaglia, G., Villa, S.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1261::1b25095fcb871f6e46cbb54744a90849
https://hdl.handle.net/2434/961660

Phagocyte-targeting polymersomes as intracellular delivery carriers for enzymatic inhibitors with antitubercular activity

Autor: Cazzaniga, G., Mori, M., Meneghetti, F., Chiarelli, L.R., Stelitano, G., Di Gugliemo, C., Batalha, I.L., Battaglia, G., Villa, S.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1261::38e856804f1e44d181ed6c46c1dc540d
https://hdl.handle.net/2434/961679