RGS10 Attenuates Systemic Immune Dysregulation Induced by Chronic Inflammatory Stress.

Autor: Jernigan JE; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Staley HA; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA., Baty Z; Department of Biomedical Engineering, College of Engineering, University of Florida, Gainesville, FL USA., Bolen ML; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Gomes BN; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Holt J; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA., Cole CL; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA., Neighbarger NK; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA., Dheeravath K; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA., Merchak AR; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Menees KB; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Coombes SA; Department of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, FL USA., Tansey MG; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 29. Date of Electronic Publication: 2024 Oct 29.

Peripheral Blood Immune Cells from Individuals with Parkinson's Disease or Inflammatory Bowel Disease Share Deficits in Iron Storage and Transport that are Modulated by Non-Steroidal Anti-Inflammatory Drugs.

Autor: Bolen ML; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Nuñes Gomes B; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA., Gill B; Department of Surgery, Northwestern University., Menees KB; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Staley H; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA., Jernigan J; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Tansey MG; Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Neuroscience, College of Medicine, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 19. Date of Electronic Publication: 2024 Aug 19.

Distinctive CD56 ^dim NK subset profiles and increased NKG2D expression in blood NK cells of Parkinson's disease patients.

Autor: Weber S; Department of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, USA., Menees KB; Department of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, USA., Park J; Harrison College of Pharmacy, Auburn University, Auburn, AL, USA., Agin-Liebes J; Department of Neurology, Columbia University Medical Center, New York, NY, USA., Lin CC; Department of Neurology, Columbia University Medical Center, New York, NY, USA., Alcalay RN; Department of Neurology, Columbia University Medical Center, New York, NY, USA.; Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel., Lee JK; Department of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, USA. jamlee@uga.edu.

Publikováno v: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2024 Feb 15; Vol. 10 (1), pp. 36. Date of Electronic Publication: 2024 Feb 15.

New Insights and Implications of Natural Killer Cells in Parkinson's Disease.

Autor: Menees KB; Department of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, USA., Lee JK; Department of Physiology and Pharmacology, University of Georgia College of Veterinary Medicine, Athens, GA, USA.

Publikováno v: Journal of Parkinson's disease [J Parkinsons Dis] 2022; Vol. 12 (s1), pp. S83-S92.

NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathy.

Autor: Earls RH; Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602., Menees KB; Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602., Chung J; Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602., Gutekunst CA; Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA 30322., Lee HJ; Department of Neurology, University of Mississippi Medical Center, Jackson, MS 39216.; Research Service, G.V. (Sonny) Montgomery VA Medical Center, Jackson, MS 39216., Hazim MG; Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA 30322., Rada B; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602., Wood LB; Coulter Department of Biomedical Engineering, Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332.; Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332., Lee JK; Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602; jamlee@uga.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 21; Vol. 117 (3), pp. 1762-1771. Date of Electronic Publication: 2020 Jan 03.