Low Bioavailability and High Immunogenicity of a New Brand of E. colil-Asparaginase with Active Host Contaminating Proteins.

Autor: Zenatti PP; Centro Infantil Boldrini, Campinas, SP, Brazil., Migita NA; Centro Infantil Boldrini, Campinas, SP, Brazil., Cury NM; Centro Infantil Boldrini, Campinas, SP, Brazil., Mendes-Silva RA; Centro Infantil Boldrini, Campinas, SP, Brazil., Gozzo FC; Chemistry Institute, State University of Campinas, Campinas, SP, Brazil., de Campos-Lima PO; Centro Infantil Boldrini, Campinas, SP, Brazil., Yunes JA; Centro Infantil Boldrini, Campinas, SP, Brazil; Medical Genetics Department, Faculty of Medical Sciences, State University of Campinas, Campinas, SP, Brazil. Electronic address: andres@boldrini.org.br., Brandalise SR; Centro Infantil Boldrini, Campinas, SP, Brazil. Electronic address: silvia@boldrini.org.br.

Publikováno v: EBioMedicine [EBioMedicine] 2018 Apr; Vol. 30, pp. 158-166. Date of Electronic Publication: 2018 Mar 09.