Zobrazeno 1 - 10 of 33 pro vyhledávání: '"Mendes, Monique S."'
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Akademický článek
An overview of microglia ontogeny and maturation in the homeostatic and pathological brain.
Autor: Mendes, Monique S.1 (AUTHOR) ania_majewska@urmc.rochester.edu, Majewska, Ania K.1,2 (AUTHOR), Dowd, Eilis (AUTHOR)
Publikováno v: European Journal of Neuroscience. Jun2021, Vol. 53 Issue 11, p3525-3547. 23p. 3 Diagrams.
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Akademický článek
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Additional file 4 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
Autor: Karaahmet, Berke, Le, Linh, Mendes, Monique S., Majewska, Ania K., O’Banion, M. Kerry
Additional file 4: Figure S4. Repopulation of microglia does not alter behavior in 21-month-old male 3xTg mice. 21-month-old 3xTg mice were treated with control or PLX5622 chow for 14 days and then returned to control chow for the remainder of the ex
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Additional file 6 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
Autor: Karaahmet, Berke, Le, Linh, Mendes, Monique S., Majewska, Ania K., O’Banion, M. Kerry
Additional file 6: Figure S6. Repopulated microglia in male APP/PS1 show similar recruitment to plaques but different homeostatic markers levels. Flow cytometry revealed similar internalization of MeX04 between control and PLX-treated groups (A). TME
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Additional file 8 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
Autor: Karaahmet, Berke, Le, Linh, Mendes, Monique S., Majewska, Ania K., O’Banion, M. Kerry
Additional file 8: Figure S8. Quality Control metrics from scRNAseq dataset. Violin plots depicting the total number of detected RNA molecules (A), number of unique genes/features (B), and percentage of mitochondrial gene contamination (C) per cell p
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Additional file 2 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
Autor: Karaahmet, Berke, Le, Linh, Mendes, Monique S., Majewska, Ania K., O’Banion, M. Kerry
Additional file 2: Figure S2. Repopulation of microglia does not ameliorate Aβ pathology and neuritic damage in APP/PS1 female mice. Representative immunofluorescent 20× images of the subiculum in control versus PLX-repopulated group, showing Aβ p
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Additional file 1 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
Autor: Karaahmet, Berke, Le, Linh, Mendes, Monique S., Majewska, Ania K., O’Banion, M. Kerry
Additional file 1: Figure S1. 2 weeks of PLX5622 administration partially eliminates microglia in 3xTg and APP/PS1 mice. Representative confocal immunofluorescent 10× images showing plaques (6E10, red) and microglia (Iba1, magenta) in the cortex and
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Additional file 3 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
Autor: Karaahmet, Berke, Le, Linh, Mendes, Monique S., Majewska, Ania K., O’Banion, M. Kerry
Additional file 3: Figure S3. Repopulation of microglia causes subtle changes in Aβ peptide levels. Hippocampal lysates from 3xTg Cohort 1 were processed to separate soluble and insoluble fractions, which were used as substrates for ELISA for Aβ42
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Additional file 5 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
Autor: Karaahmet, Berke, Le, Linh, Mendes, Monique S., Majewska, Ania K., O’Banion, M. Kerry
Additional file 5: Figure S5. Gating strategy for 3xTg and APP/PS1 flow cytometry experiments. Briefly, debris was excluded based on SSC and FSC properties, and live cells were selected by gating for singlets and 7-AAD− events. Microglia were defin
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Additional file 7 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
Autor: Karaahmet, Berke, Le, Linh, Mendes, Monique S., Majewska, Ania K., O’Banion, M. Kerry
Additional file 7: Figure S7. Repopulated microglia in female APP/PS1 show similar recruitment to plaques but different activated marker levels. Flow cytometry revealed similar internalization of MeX04 between control and PLX treatment groups (A). Wh
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