Asymmetric Hydrogenation of Indazole-Containing Enamides Relevant to the Synthesis of Zavegepant Using Neutral and Cationic Cobalt Precatalysts.

Autor: Mendelsohn LN; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States., MacNeil CS; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States., Esposito MR; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States., Pabst TP; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States., Leahy DK; Biohaven, LTD, New Haven, Connecticut 06510, United States., Davies IW; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States., Chirik PJ; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.

Publikováno v: Organic letters [Org Lett] 2024 Apr 12; Vol. 26 (14), pp. 2718-2723. Date of Electronic Publication: 2023 Jun 04.

Mechanistic Investigations of the Asymmetric Hydrogenation of Enamides with Neutral Bis(phosphine) Cobalt Precatalysts.

Autor: Mendelsohn LN; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States., Pavlovic L; Department of Chemistry, UiT - The Arctic University of Norway, Tromsø N-9037, Norway., Zhong H; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States., Friedfeld MR; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States., Shevlin M; Department of Process Research & Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States., Hopmann KH; Department of Chemistry, UiT - The Arctic University of Norway, Tromsø N-9037, Norway., Chirik PJ; Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2022 Aug 31; Vol. 144 (34), pp. 15764-15778. Date of Electronic Publication: 2022 Aug 11.

Synthesis and Reactivity of Organometallic Intermediates Relevant to Cobalt-Catalyzed Hydroformylation.

Autor: MacNeil CS; Department of Chemistry, Princeton University, Frick Laboratory 292, Princeton, NJ, 08544, USA., Mendelsohn LN; Department of Chemistry, Princeton University, Frick Laboratory 292, Princeton, NJ, 08544, USA., Zhong H; Department of Chemistry, Princeton University, Frick Laboratory 292, Princeton, NJ, 08544, USA., Pabst TP; Department of Chemistry, Princeton University, Frick Laboratory 292, Princeton, NJ, 08544, USA., Chirik PJ; Department of Chemistry, Princeton University, Frick Laboratory 292, Princeton, NJ, 08544, USA.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2020 Jun 02; Vol. 59 (23), pp. 8912-8916. Date of Electronic Publication: 2020 Mar 30.

Shuttle HAT for mild alkene transfer hydrofunctionalization.

Autor: Jankins, Tanner C., Blank, Philip M., Brugnetti, Andrea, Boehm, Philip, Aouane, Françoise A., Morandi, Bill

Publikováno v: Nature Communications; 10/30/2024, Vol. 15 Issue 1, p1-9, 9p

Synthetic techniques for thermodynamically disfavoured substituted six-membered rings.

Autor: Li, Yangyang, Shi, Hongjin, Yin, Guoyin

Publikováno v: Nature Reviews Chemistry; Jul2024, Vol. 8 Issue 7, p535-550, 16p